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6. The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors. Stokes C; Papke JK; Horenstein NA; Kem WR; McCormack TJ; Papke RL Mol Pharmacol; 2004 Jul; 66(1):14-24. PubMed ID: 15213292 [TBL] [Abstract][Full Text] [Related]
7. The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21). Kem WR Behav Brain Res; 2000 Aug; 113(1-2):169-81. PubMed ID: 10942043 [TBL] [Abstract][Full Text] [Related]
8. A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein. Slavov SH; Radzvilovits M; LeFrancois S; Stoyanova-Slavova IB; Soti F; Kem WR; Katritzky AR Eur J Med Chem; 2010 Jun; 45(6):2433-46. PubMed ID: 20236734 [TBL] [Abstract][Full Text] [Related]
9. Theoretical studies of Alzheimer's disease drug candidate 3-[(2,4-dimethoxy)benzylidene]-anabaseine (GTS-21) and its derivatives. Wei DQ; Sirois S; Du QS; Arias HR; Chou KC Biochem Biophys Res Commun; 2005 Dec; 338(2):1059-64. PubMed ID: 16256952 [TBL] [Abstract][Full Text] [Related]
10. Anabaseine is a potent agonist on muscle and neuronal alpha-bungarotoxin-sensitive nicotinic receptors. Kem WR; Mahnir VM; Papke RL; Lingle CJ J Pharmacol Exp Ther; 1997 Dec; 283(3):979-92. PubMed ID: 9399967 [TBL] [Abstract][Full Text] [Related]
11. Interaction of benzylidene-anabaseine analogues with agonist and allosteric sites on muscle nicotinic acetylcholine receptors. Arias HR; Xing H; Macdougall K; Blanton MP; Soti F; Kem WR Br J Pharmacol; 2009 May; 157(2):320-30. PubMed ID: 19338581 [TBL] [Abstract][Full Text] [Related]
13. Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders. Roncarati R; Scali C; Comery TA; Grauer SM; Aschmi S; Bothmann H; Jow B; Kowal D; Gianfriddo M; Kelley C; Zanelli U; Ghiron C; Haydar S; Dunlop J; Terstappen GC J Pharmacol Exp Ther; 2009 May; 329(2):459-68. PubMed ID: 19223665 [TBL] [Abstract][Full Text] [Related]
14. Alpha7 nicotinic acetylcholine receptor-specific agonist DMXBA (GTS-21) attenuates Aβ accumulation through suppression of neuronal γ-secretase activity and promotion of microglial amyloid-β phagocytosis and ameliorates cognitive impairment in a mouse model of Alzheimer's disease. Takata K; Amamiya T; Mizoguchi H; Kawanishi S; Kuroda E; Kitamura R; Ito A; Saito Y; Tawa M; Nagasawa T; Okamoto H; Sugino Y; Takegami S; Kitade T; Toda Y; Kem WR; Kitamura Y; Shimohama S; Ashihara E Neurobiol Aging; 2018 Feb; 62():197-209. PubMed ID: 29175709 [TBL] [Abstract][Full Text] [Related]
15. Pharmacokinetics and urinary excretion of DMXBA (GTS-21), a compound enhancing cognition. Mahnir V; Lin B; Prokai-Tatrai K; Kem WR Biopharm Drug Dispos; 1998 Apr; 19(3):147-51. PubMed ID: 9569996 [TBL] [Abstract][Full Text] [Related]
16. Synthesis and positron emission tomography studies of C-11-labeled isotopomers and metabolites of GTS-21, a partial alpha7 nicotinic cholinergic agonist drug. Kim SW; Ding YS; Alexoff D; Patel V; Logan J; Lin KS; Shea C; Muench L; Xu Y; Carter P; King P; Constanzo JR; Ciaccio JA; Fowler JS Nucl Med Biol; 2007 Jul; 34(5):541-51. PubMed ID: 17591554 [TBL] [Abstract][Full Text] [Related]
17. N-terminal domains in mouse and human 5-hydroxytryptamine3A receptors confer partial agonist and antagonist properties to benzylidene analogs of anabaseine. Zhang R; White NA; Soti FS; Kem WR; Machu TK J Pharmacol Exp Ther; 2006 Jun; 317(3):1276-84. PubMed ID: 16551836 [TBL] [Abstract][Full Text] [Related]
18. Metabolism and disposition of GTS-21, a novel drug for Alzheimer's disease. Azuma R; Komuro M; Korsch BH; Andre JC; Onnagawa O; Black SR; Mathews JM Xenobiotica; 1999 Jul; 29(7):747-62. PubMed ID: 10456692 [TBL] [Abstract][Full Text] [Related]
19. Schizophrenia and the alpha7 nicotinic acetylcholine receptor. Martin LF; Freedman R Int Rev Neurobiol; 2007; 78():225-46. PubMed ID: 17349863 [TBL] [Abstract][Full Text] [Related]