BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

288 related articles for article (PubMed ID: 14724564)

  • 21. Intrinsic anticancer drug resistance of malignant melanoma cells is abrogated by IFN-β and valproic acid.
    Roos WP; Jöst E; Belohlavek C; Nagel G; Fritz G; Kaina B
    Cancer Res; 2011 Jun; 71(12):4150-60. PubMed ID: 21493591
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine.
    Kokkinakis DM; Ahmed MM; Chendil D; Moschel RC; Pegg AE
    Clin Cancer Res; 2003 Sep; 9(10 Pt 1):3801-7. PubMed ID: 14506174
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide.
    Eich M; Roos WP; Dianov GL; Digweed M; Kaina B
    Mol Pharmacol; 2010 Nov; 78(5):943-51. PubMed ID: 20729302
    [TBL] [Abstract][Full Text] [Related]  

  • 24. DNA double-strand breaks trigger apoptosis in p53-deficient fibroblasts.
    Lips J; Kaina B
    Carcinogenesis; 2001 Apr; 22(4):579-85. PubMed ID: 11285192
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication.
    Aghi M; Rabkin S; Martuza RL
    J Natl Cancer Inst; 2006 Jan; 98(1):38-50. PubMed ID: 16391370
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system.
    Alvino E; Castiglia D; Caporali S; Pepponi R; Caporaso P; Lacal PM; Marra G; Fischer F; Zambruno G; Bonmassar E; Jiricny J; D'Atri S
    Int J Oncol; 2006 Oct; 29(4):785-97. PubMed ID: 16964376
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Effect of O6-alkylguanine-DNA alkyltransferase on the frequency and spectrum of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in the HPRT gene of diploid human fibroblasts.
    Lukash LL; Boldt J; Pegg AE; Dolan ME; Maher VM; McCormick JJ
    Mutat Res; 1991; 250(1-2):397-409. PubMed ID: 1944354
    [TBL] [Abstract][Full Text] [Related]  

  • 28. O6-methylguanine (O6-MeG) and cytotoxicity: reversion analysis involving an N-methyl-N'-nitro-N-nitrosoguanidine-sensitive, O6-MeG-DNA methyltransferase-deficient HeLa cell mutant.
    Kalamegham R; Ebisuzaki K
    Carcinogenesis; 1990 May; 11(5):777-80. PubMed ID: 2335006
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents.
    Hickman MJ; Samson LD
    Proc Natl Acad Sci U S A; 1999 Sep; 96(19):10764-9. PubMed ID: 10485900
    [TBL] [Abstract][Full Text] [Related]  

  • 30. O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation.
    Noonan EM; Shah D; Yaffe MB; Lauffenburger DA; Samson LD
    Integr Biol (Camb); 2012 Oct; 4(10):1237-55. PubMed ID: 22892544
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Temozolomide-mediated DNA methylation in human myeloid precursor cells: differential involvement of intrinsic and extrinsic apoptotic pathways.
    Wang H; Cai S; Ernstberger A; Bailey BJ; Wang MZ; Cai W; Goebel WS; Czader MB; Crean C; Suvannasankha A; Shokolenkoc I; Wilson GL; Baluyut AR; Mayo LD; Pollok KE
    Clin Cancer Res; 2013 May; 19(10):2699-709. PubMed ID: 23536437
    [TBL] [Abstract][Full Text] [Related]  

  • 32. RAD51D protects against MLH1-dependent cytotoxic responses to O(6)-methylguanine.
    Rajesh P; Rajesh C; Wyatt MD; Pittman DL
    DNA Repair (Amst); 2010 Apr; 9(4):458-67. PubMed ID: 20133210
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Repair and removal of azoxymethane-induced O6-methylguanine in rat colon by O6-methylguanine DNA methyltransferase and apoptosis.
    Nyskohus LS; Watson AJ; Margison GP; Le Leu RK; Kim SW; Lockett TJ; Head RJ; Young GP; Hu Y
    Mutat Res Genet Toxicol Environ Mutagen; 2013 Dec; 758(1-2):80-6. PubMed ID: 24140386
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The trophic action of IL-7 on pro-T cells: inhibition of apoptosis of pro-T1, -T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways.
    Kim K; Lee CK; Sayers TJ; Muegge K; Durum SK
    J Immunol; 1998 Jun; 160(12):5735-41. PubMed ID: 9637482
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agents.
    Christmann M; Kaina B
    J Biol Chem; 2000 Nov; 275(46):36256-62. PubMed ID: 10954713
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Triazene compounds: mechanism of action and related DNA repair systems.
    Marchesi F; Turriziani M; Tortorelli G; Avvisati G; Torino F; De Vecchis L
    Pharmacol Res; 2007 Oct; 56(4):275-87. PubMed ID: 17897837
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Fas/APO-1 by irradiation and ara-C treatment.
    Kobayashi T; Ruan S; Jabbur JR; Consoli U; Clodi K; Shiku H; Owen-Schaub LB; Andreeff M; Reed JC; Zhang W
    Cell Death Differ; 1998 Jul; 5(7):584-91. PubMed ID: 10200513
    [TBL] [Abstract][Full Text] [Related]  

  • 38. O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.
    Hermisson M; Klumpp A; Wick W; Wischhusen J; Nagel G; Roos W; Kaina B; Weller M
    J Neurochem; 2006 Feb; 96(3):766-76. PubMed ID: 16405512
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Expression of Apo-1/Fas (CD95), Bcl-2, Bax and Bcl-x in myeloma cell lines: relationship between responsiveness to anti-Fas mab and p53 functional status.
    Egle A; Villunger A; Marschitz I; Kos M; Hittmair A; Lukas P; Grünewald K; Greil R
    Br J Haematol; 1997 May; 97(2):418-28. PubMed ID: 9163609
    [TBL] [Abstract][Full Text] [Related]  

  • 40. ATM is activated in response to N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA alkylation.
    Adamson AW; Kim WJ; Shangary S; Baskaran R; Brown KD
    J Biol Chem; 2002 Oct; 277(41):38222-9. PubMed ID: 12151394
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.