BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

735 related articles for article (PubMed ID: 14726529)

  • 1. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.
    Zhou J; Schmid T; Frank R; Brüne B
    J Biol Chem; 2004 Apr; 279(14):13506-13. PubMed ID: 14726529
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyltransferase inhibitor SCH66336 in human aerodigestive tract cancer.
    Han JY; Oh SH; Morgillo F; Myers JN; Kim E; Hong WK; Lee HY
    J Natl Cancer Inst; 2005 Sep; 97(17):1272-86. PubMed ID: 16145048
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization.
    Katschinski DM; Le L; Schindler SG; Thomas T; Voss AK; Wenger RH
    Cell Physiol Biochem; 2004; 14(4-6):351-60. PubMed ID: 15319539
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ηypoxia-inducible factor-1α, von Hippel-Lindau protein, and heat shock protein expression in ophthalmic pterygium and normal conjunctiva.
    Pagoulatos D; Pharmakakis N; Lakoumentas J; Assimakopoulou M
    Mol Vis; 2014; 20():441-57. PubMed ID: 24715760
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells.
    Li YM; Zhou BP; Deng J; Pan Y; Hay N; Hung MC
    Cancer Res; 2005 Apr; 65(8):3257-63. PubMed ID: 15833858
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).
    Schmid T; Zhou J; Köhl R; Brüne B
    Biochem J; 2004 May; 380(Pt 1):289-95. PubMed ID: 14992692
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization.
    Liu YV; Hubbi ME; Pan F; McDonald KR; Mansharamani M; Cole RN; Liu JO; Semenza GL
    J Biol Chem; 2007 Dec; 282(51):37064-73. PubMed ID: 17965024
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 4-Hydroxy estradiol but not 2-hydroxy estradiol induces expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor A through phosphatidylinositol 3-kinase/Akt/FRAP pathway in OVCAR-3 and A2780-CP70 human ovarian carcinoma cells.
    Gao N; Nester RA; Sarkar MA
    Toxicol Appl Pharmacol; 2004 Apr; 196(1):124-35. PubMed ID: 15050414
    [TBL] [Abstract][Full Text] [Related]  

  • 10. COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70.
    van de Sluis B; Groot AJ; Vermeulen J; van der Wall E; van Diest PJ; Wijmenga C; Klomp LW; Vooijs M
    PLoS One; 2009 Oct; 4(10):e7332. PubMed ID: 19802386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Histone deacetylase inhibitor induced pVHL-independent degradation of HIF-1α and hierarchical quality control of pVHL via chaperone system.
    Ni J; Ni A
    PLoS One; 2021; 16(7):e0248019. PubMed ID: 34329303
    [TBL] [Abstract][Full Text] [Related]  

  • 12. JNK1 mediates degradation HIF-1alpha by a VHL-independent mechanism that involves the chaperones Hsp90/Hsp70.
    Zhang D; Li J; Costa M; Gao J; Huang C
    Cancer Res; 2010 Jan; 70(2):813-23. PubMed ID: 20068160
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product.
    Pereira T; Zheng X; Ruas JL; Tanimoto K; Poellinger L
    J Biol Chem; 2003 Feb; 278(9):6816-23. PubMed ID: 12468553
    [TBL] [Abstract][Full Text] [Related]  

  • 14. VEGF production by primary human renal proximal tubular cells: requirement of HIF-1, PI3-kinase and MAPKK-1 signaling.
    Hellwig-Bürgel T; Stiehl DP; Katschinski DM; Marxsen J; Kreft B; Jelkmann W
    Cell Physiol Biochem; 2005; 15(1-4):99-108. PubMed ID: 15665520
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha.
    Liu YV; Baek JH; Zhang H; Diez R; Cole RN; Semenza GL
    Mol Cell; 2007 Jan; 25(2):207-17. PubMed ID: 17244529
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RACK1 vs. HSP90: competition for HIF-1 alpha degradation vs. stabilization.
    Liu YV; Semenza GL
    Cell Cycle; 2007 Mar; 6(6):656-9. PubMed ID: 17361105
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells.
    Mottet D; Dumont V; Deccache Y; Demazy C; Ninane N; Raes M; Michiels C
    J Biol Chem; 2003 Aug; 278(33):31277-85. PubMed ID: 12764143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Immunoexpression patterns for Hypoxia-inducible Factor-1α and von Hippel-Lindau protein, in relation to Hsp90, of human brain tumors.
    Assimakopoulou M; Androutsopoulou C; Zolota V; Matsoukas J
    Histol Histopathol; 2016 May; 31(5):535-46. PubMed ID: 26592496
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA-dependent protein kinase is involved in heat shock protein-mediated accumulation of hypoxia-inducible factor-1alpha in hypoxic preconditioned HepG2 cells.
    Kang MJ; Jung SM; Kim MJ; Bae JH; Kim HB; Kim JY; Park SJ; Song HS; Kim DW; Kang CD; Kim SH
    FEBS J; 2008 Dec; 275(23):5969-81. PubMed ID: 19021771
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of hypoxia-induced transcription in normoxia.
    Hägg M; Wennström S
    Exp Cell Res; 2005 May; 306(1):180-91. PubMed ID: 15878343
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 37.