BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 14729674)

  • 1. Distinct roles for the catalytic and hemopexin domains of membrane type 1-matrix metalloproteinase in substrate degradation and cell migration.
    Cao J; Kozarekar P; Pavlaki M; Chiarelli C; Bahou WF; Zucker S
    J Biol Chem; 2004 Apr; 279(14):14129-39. PubMed ID: 14729674
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The hemopexin domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) Is not required for its activation of proMMP2 on cell surface but is essential for MT1-MMP-mediated invasion in three-dimensional type I collagen.
    Wang P; Nie J; Pei D
    J Biol Chem; 2004 Dec; 279(49):51148-55. PubMed ID: 15381707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CD44 binding through the hemopexin-like domain is critical for its shedding by membrane-type 1 matrix metalloproteinase.
    Suenaga N; Mori H; Itoh Y; Seiki M
    Oncogene; 2005 Jan; 24(5):859-68. PubMed ID: 15558018
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Domain interactions in the gelatinase A.TIMP-2.MT1-MMP activation complex. The ectodomain of the 44-kDa form of membrane type-1 matrix metalloproteinase does not modulate gelatinase A activation.
    Overall CM; Tam E; McQuibban GA; Morrison C; Wallon UM; Bigg HF; King AE; Roberts CR
    J Biol Chem; 2000 Dec; 275(50):39497-506. PubMed ID: 10991943
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rac1 mediates type I collagen-dependent MMP-2 activation. role in cell invasion across collagen barrier.
    Zhuge Y; Xu J
    J Biol Chem; 2001 May; 276(19):16248-56. PubMed ID: 11340084
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage.
    Tam EM; Wu YI; Butler GS; Stack MS; Overall CM
    J Biol Chem; 2002 Oct; 277(41):39005-14. PubMed ID: 12145314
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain.
    Mori H; Tomari T; Koshikawa N; Kajita M; Itoh Y; Sato H; Tojo H; Yana I; Seiki M
    EMBO J; 2002 Aug; 21(15):3949-59. PubMed ID: 12145196
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of the hemopexin domain of matrix metalloproteinases in cell migration.
    Dufour A; Sampson NS; Zucker S; Cao J
    J Cell Physiol; 2008 Dec; 217(3):643-51. PubMed ID: 18636552
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oligomerization through hemopexin and cytoplasmic domains regulates the activity and turnover of membrane-type 1 matrix metalloproteinase.
    Lehti K; Lohi J; Juntunen MM; Pei D; Keski-Oja J
    J Biol Chem; 2002 Mar; 277(10):8440-8. PubMed ID: 11779859
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of the distinct collagen binding, helicase and cleavage mechanisms of matrix metalloproteinase 2 and 14 (gelatinase A and MT1-MMP): the differential roles of the MMP hemopexin c domains and the MMP-2 fibronectin type II modules in collagen triple helicase activities.
    Tam EM; Moore TR; Butler GS; Overall CM
    J Biol Chem; 2004 Oct; 279(41):43336-44. PubMed ID: 15292230
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells.
    Rozanov DV; Hahn-Dantona E; Strickland DK; Strongin AY
    J Biol Chem; 2004 Feb; 279(6):4260-8. PubMed ID: 14645246
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutational and structural analyses of the hinge region of membrane type 1-matrix metalloproteinase and enzyme processing.
    Osenkowski P; Meroueh SO; Pavel D; Mobashery S; Fridman R
    J Biol Chem; 2005 Jul; 280(28):26160-8. PubMed ID: 15901740
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Membrane type-1-matrix metalloproteinase expressed by prostate carcinoma cells cleaves human laminin-5 beta3 chain and induces cell migration.
    Udayakumar TS; Chen ML; Bair EL; Von Bredow DC; Cress AE; Nagle RB; Bowden GT
    Cancer Res; 2003 May; 63(9):2292-9. PubMed ID: 12727852
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Catalytic Domain Mediates Homomultimerization of MT1-MMP and the Prodomain Interferes with MT1-MMP Oligomeric Complex Assembly.
    Fogarasi M; Dima S
    Biomolecules; 2022 Aug; 12(8):. PubMed ID: 36009039
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MT1-MMP hemopexin domain exchange with MT4-MMP blocks enzyme maturation and trafficking to the plasma membrane in MCF7 cells.
    Atkinson SJ; Roghi C; Murphy G
    Biochem J; 2006 Aug; 398(1):15-22. PubMed ID: 16686598
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.
    Itoh Y; Takamura A; Ito N; Maru Y; Sato H; Suenaga N; Aoki T; Seiki M
    EMBO J; 2001 Sep; 20(17):4782-93. PubMed ID: 11532942
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Membrane type 1-matrix metalloproteinase promotes human prostate cancer invasion and metastasis.
    Cao J; Chiarelli C; Kozarekar P; Adler HL
    Thromb Haemost; 2005 Apr; 93(4):770-8. PubMed ID: 15841326
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Membrane type-1 matrix metalloproteinase (MT1-MMP) processing of pro-alphav integrin regulates cross-talk between alphavbeta3 and alpha2beta1 integrins in breast carcinoma cells.
    Baciu PC; Suleiman EA; Deryugina EI; Strongin AY
    Exp Cell Res; 2003 Nov; 291(1):167-75. PubMed ID: 14597417
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glycosylation broadens the substrate profile of membrane type 1 matrix metalloproteinase.
    Wu YI; Munshi HG; Sen R; Snipas SJ; Salvesen GS; Fridman R; Stack MS
    J Biol Chem; 2004 Feb; 279(9):8278-89. PubMed ID: 14670950
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of the extracellular signal-regulated protein kinase (ERK) cascade by membrane-type-1 matrix metalloproteinase (MT1-MMP).
    Gingras D; Bousquet-Gagnon N; Langlois S; Lachambre MP; Annabi B; BĂ©liveau R
    FEBS Lett; 2001 Oct; 507(2):231-6. PubMed ID: 11684104
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.