BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 1473224)

  • 1. Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57BL/6 mice and in human MCL-5 cells.
    White IN; de Matteis F; Davies A; Smith LL; Crofton-Sleigh C; Venitt S; Hewer A; Phillips DH
    Carcinogenesis; 1992 Dec; 13(12):2197-203. PubMed ID: 1473224
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Clastogenic and aneugenic effects of tamoxifen and some of its analogues in hepatocytes from dosed rats and in human lymphoblastoid cells transfected with human P450 cDNAs (MCL-5 cells).
    Styles JA; Davies A; Davies R; White IN; Smith LL
    Carcinogenesis; 1997 Feb; 18(2):303-13. PubMed ID: 9054622
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genotoxic effects of the novel mixed antiestrogen FC-1271a in comparison to tamoxifen and toremifene.
    Hellmann-Blumberg U; Taras TL; Wurz GT; DeGregorio MW
    Breast Cancer Res Treat; 2000 Mar; 60(1):63-70. PubMed ID: 10845810
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Delayed effects of tamoxifen in hepatocarcinogenesis-resistant Fischer 344 rats as compared with susceptible strains.
    Stanley LA; Carthew P; Davies R; Higginson F; Martin E; Styles JA
    Cancer Lett; 2001 Sep; 171(1):27-35. PubMed ID: 11485825
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Induction of CYP2B1 and 3A1, and associated monoxygenase activities by tamoxifen and certain analogues in the livers of female rats and mice.
    White IN; Davies A; Smith LL; Dawson S; De Matteis F
    Biochem Pharmacol; 1993 Jan; 45(1):21-30. PubMed ID: 8424814
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Toxicology and carcinogenesis studies of riddelliine (CAS No. 23246-96-0) in F344/N rats and B6C3F1 mice (gavage studies).
    National Toxicology Program
    Natl Toxicol Program Tech Rep Ser; 2003 May; (508):1-280. PubMed ID: 12844193
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Determination of DNA damage in F344 rats induced by geometric isomers of tamoxifen and analogues.
    Brown K; Brown JE; Martin EA; Smith LL; White IN
    Chem Res Toxicol; 1998 May; 11(5):527-34. PubMed ID: 9585484
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cumulative exposure to tamoxifen: DNA adducts and liver cancer in the rat.
    Carthew P; Lee PN; Edwards RE; Heydon RT; Nolan BM; Martin EA
    Arch Toxicol; 2001 Aug; 75(6):375-80. PubMed ID: 11570696
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sex differences in the activation of tamoxifen to DNA binding species in rat liver in vivo and in rat hepatocytes in vitro: role of sulfotransferase induction.
    Davis W; Hewer A; Rajkowski KM; Meinl W; Glatt H; Phillips DH
    Cancer Res; 2000 Jun; 60(11):2887-91. PubMed ID: 10850433
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tamoxifen: evidence by 32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite.
    Randerath K; Moorthy B; Mabon N; Sriram P
    Carcinogenesis; 1994 Oct; 15(10):2087-94. PubMed ID: 7955037
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of tamoxifen and alpha-hydroxytamoxifen 32P-post-labelled DNA adducts by the development of a novel automated on-line solid-phase extraction HPLC method.
    Martin EA; Heydon RT; Brown K; Brown JE; Lim CK; White IN; Smith LL
    Carcinogenesis; 1998 Jun; 19(6):1061-9. PubMed ID: 9667745
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Investigation of the formation and accumulation of liver DNA adducts in mice chronically exposed to tamoxifen.
    Martin EA; Carthew P; White IN; Heydon RT; Gaskell M; Mauthe RJ; Turteltaub KW; Smith LL
    Carcinogenesis; 1997 Nov; 18(11):2209-15. PubMed ID: 9395223
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Major difference in the hepatocarcinogenicity and DNA adduct forming ability between toremifene and tamoxifen in female Crl:CD(BR) rats.
    Hard GC; Iatropoulos MJ; Jordan K; Radi L; Kaltenberg OP; Imondi AR; Williams GM
    Cancer Res; 1993 Oct; 53(19):4534-41. PubMed ID: 8402624
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA damage as assessed by 32P-postlabelling in three rat strains exposed to dietary tamoxifen: the relationship between cell proliferation and liver tumour formation.
    Carthew P; Rich KJ; Martin EA; De Matteis F; Lim CK; Manson MM; Festing MF; White IN; Smith LL
    Carcinogenesis; 1995 Jun; 16(6):1299-304. PubMed ID: 7788846
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA adduct formation and T lymphocyte mutation induction in F344 rats implanted with tumorigenic doses of 1,6-dinitropyrene.
    Beland FA
    Res Rep Health Eff Inst; 1995 Oct; (72):1-27; discussion 29-39. PubMed ID: 11381742
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of chronic administration of tamoxifen and toremifene on DNA adducts in rat liver, kidney, and uterus.
    Li D; Dragan Y; Jordan VC; Wang M; Pitot HC
    Cancer Res; 1997 Apr; 57(8):1438-41. PubMed ID: 9108442
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Toxicity of antiestrogens.
    Hirsimäki P; Aaltonen A; Mäntylä E
    Breast J; 2002; 8(2):92-6. PubMed ID: 11896754
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s.
    Styles JA; Davies A; Lim CK; De Matteis F; Stanley LA; White IN; Yuan ZX; Smith LL
    Carcinogenesis; 1994 Jan; 15(1):5-9. PubMed ID: 8293548
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Organ specificity of DNA adduct formation by tamoxifen and alpha-hydroxytamoxifen in the rat: implications for understanding the mechanism(s) of tamoxifen carcinogenicity and for human risk assessment.
    Phillips DH; Hewer A; Osborne MR; Cole KJ; Churchill C; Arlt VM
    Mutagenesis; 2005 Jul; 20(4):297-303. PubMed ID: 15928012
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.