255 related articles for article (PubMed ID: 14734545)
1. Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor.
Linke S; Stojkoski C; Kewley RJ; Booker GW; Whitelaw ML; Peet DJ
J Biol Chem; 2004 Apr; 279(14):14391-7. PubMed ID: 14734545
[TBL] [Abstract][Full Text] [Related]
2. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
[TBL] [Abstract][Full Text] [Related]
3. Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
Hewitson KS; McNeill LA; Riordan MV; Tian YM; Bullock AN; Welford RW; Elkins JM; Oldham NJ; Bhattacharya S; Gleadle JM; Ratcliffe PJ; Pugh CW; Schofield CJ
J Biol Chem; 2002 Jul; 277(29):26351-5. PubMed ID: 12042299
[TBL] [Abstract][Full Text] [Related]
4. MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH).
Webb JD; Murányi A; Pugh CW; Ratcliffe PJ; Coleman ML
Biochem J; 2009 May; 420(2):327-33. PubMed ID: 19245366
[TBL] [Abstract][Full Text] [Related]
5. Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.
Coleman ML; McDonough MA; Hewitson KS; Coles C; Mecinovic J; Edelmann M; Cook KM; Cockman ME; Lancaster DE; Kessler BM; Oldham NJ; Ratcliffe PJ; Schofield CJ
J Biol Chem; 2007 Aug; 282(33):24027-38. PubMed ID: 17573339
[TBL] [Abstract][Full Text] [Related]
6. Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
Cockman ME; Webb JD; Kramer HB; Kessler BM; Ratcliffe PJ
Mol Cell Proteomics; 2009 Mar; 8(3):535-46. PubMed ID: 18936059
[TBL] [Abstract][Full Text] [Related]
7. Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway.
Dann CE; Bruick RK; Deisenhofer J
Proc Natl Acad Sci U S A; 2002 Nov; 99(24):15351-6. PubMed ID: 12432100
[TBL] [Abstract][Full Text] [Related]
8. Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).
Wilkins SE; Hyvärinen J; Chicher J; Gorman JJ; Peet DJ; Bilton RL; Koivunen P
Int J Biochem Cell Biol; 2009 Jul; 41(7):1563-71. PubMed ID: 19401150
[TBL] [Abstract][Full Text] [Related]
9. Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
Cockman ME; Lancaster DE; Stolze IP; Hewitson KS; McDonough MA; Coleman ML; Coles CH; Yu X; Hay RT; Ley SC; Pugh CW; Oldham NJ; Masson N; Schofield CJ; Ratcliffe PJ
Proc Natl Acad Sci U S A; 2006 Oct; 103(40):14767-72. PubMed ID: 17003112
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of the Oxygen-Sensing Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-Inducible Factor: A Potential Hypoxia Response Modulating Strategy.
Wu Y; Li Z; McDonough MA; Schofield CJ; Zhang X
J Med Chem; 2021 Jun; 64(11):7189-7209. PubMed ID: 34029087
[TBL] [Abstract][Full Text] [Related]
11. Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH.
Jin P; Kang J; Lee MK; Park JW
Biochem Biophys Res Commun; 2018 May; 499(3):475-481. PubMed ID: 29580991
[TBL] [Abstract][Full Text] [Related]
12. Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha.
Shin DH; Li SH; Yang SW; Lee BL; Lee MK; Park JW
FEBS J; 2009 Jul; 276(13):3470-80. PubMed ID: 19456861
[TBL] [Abstract][Full Text] [Related]
13. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor.
Lando D; Peet DJ; Gorman JJ; Whelan DA; Whitelaw ML; Bruick RK
Genes Dev; 2002 Jun; 16(12):1466-71. PubMed ID: 12080085
[TBL] [Abstract][Full Text] [Related]
14. Factor inhibiting HIF (FIH) recognizes distinct molecular features within hypoxia-inducible factor-α (HIF-α) versus ankyrin repeat substrates.
Wilkins SE; Karttunen S; Hampton-Smith RJ; Murchland I; Chapman-Smith A; Peet DJ
J Biol Chem; 2012 Mar; 287(12):8769-81. PubMed ID: 22270367
[TBL] [Abstract][Full Text] [Related]
15. Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803.
McNeill LA; Hewitson KS; Claridge TD; Seibel JF; Horsfall LE; Schofield CJ
Biochem J; 2002 Nov; 367(Pt 3):571-5. PubMed ID: 12215170
[TBL] [Abstract][Full Text] [Related]
16. Regulation of HIF: asparaginyl hydroxylation.
Peet D; Linke S
Novartis Found Symp; 2006; 272():37-49; discussion 49-53, 131-40. PubMed ID: 16686428
[TBL] [Abstract][Full Text] [Related]
17. Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway.
Chen DY; Fabrizio JA; Wilkins SE; Dave KA; Gorman JJ; Gleadle JM; Fleming SB; Peet DJ; Mercer AA
J Virol; 2017 Jan; 91(1):. PubMed ID: 27795413
[TBL] [Abstract][Full Text] [Related]
18. Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau.
Lee C; Kim SJ; Jeong DG; Lee SM; Ryu SE
J Biol Chem; 2003 Feb; 278(9):7558-63. PubMed ID: 12482756
[TBL] [Abstract][Full Text] [Related]
19. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
Stolze IP; Tian YM; Appelhoff RJ; Turley H; Wykoff CC; Gleadle JM; Ratcliffe PJ
J Biol Chem; 2004 Oct; 279(41):42719-25. PubMed ID: 15302861
[TBL] [Abstract][Full Text] [Related]
20. The zinc chelator, N,N,N',N'-tetrakis (2-pyridylmethyl) ethylenediamine, increases the level of nonfunctional HIF-1alpha protein in normoxic cells.
Choi SM; Choi KO; Lee N; Oh M; Park H
Biochem Biophys Res Commun; 2006 May; 343(4):1002-8. PubMed ID: 16579968
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
