355 related articles for article (PubMed ID: 14742211)
21. Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.
Warrilow AG; Melo N; Martel CM; Parker JE; Nes WD; Kelly SL; Kelly DE
Antimicrob Agents Chemother; 2010 Oct; 54(10):4225-34. PubMed ID: 20660663
[TBL] [Abstract][Full Text] [Related]
22. Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents.
Sanglard D; Ischer F; Koymans L; Bille J
Antimicrob Agents Chemother; 1998 Feb; 42(2):241-53. PubMed ID: 9527767
[TBL] [Abstract][Full Text] [Related]
23.
Colley T; Sehra G; Chowdhary A; Alanio A; Kelly SL; Kizawa Y; Armstrong-James D; Fisher MC; Warrilow AGS; Parker JE; Kelly DE; Kimura G; Nishimoto Y; Sunose M; Onions S; Crepin D; Lagasse F; Crittall M; Shannon J; McConville M; King-Underwood J; Naylor A; Bretagne S; Murray J; Ito K; Strong P; Rapeport G
Antimicrob Agents Chemother; 2018 May; 62(5):. PubMed ID: 29439966
[TBL] [Abstract][Full Text] [Related]
24. Contribution of mutations in the cytochrome P450 14alpha-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans.
Marichal P; Koymans L; Willemsens S; Bellens D; Verhasselt P; Luyten W; Borgers M; Ramaekers FCS; Odds FC; Vanden Bossche H
Microbiology (Reading); 1999 Oct; 145 ( Pt 10)():2701-2713. PubMed ID: 10537192
[TBL] [Abstract][Full Text] [Related]
25. Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs.
Hargrove TY; Wawrzak Z; Lamb DC; Guengerich FP; Lepesheva GI
J Biol Chem; 2015 Sep; 290(39):23916-34. PubMed ID: 26269599
[TBL] [Abstract][Full Text] [Related]
26. Heterologous Expression of Full-Length Lanosterol 14α-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provides Tools for Antifungal Discovery.
Keniya MV; Ruma YN; Tyndall JDA; Monk BC
Antimicrob Agents Chemother; 2018 Nov; 62(11):. PubMed ID: 30126959
[TBL] [Abstract][Full Text] [Related]
27. Molecular design of two sterol 14alpha-demethylase homology models and their interactions with the azole antifungals ketoconazole and bifonazole.
Rupp B; Raub S; Marian C; Höltje HD
J Comput Aided Mol Des; 2005 Mar; 19(3):149-63. PubMed ID: 16059669
[TBL] [Abstract][Full Text] [Related]
28. A newly identified amino acid substitution T123I in the 14α-demethylase (Erg11p) of Candida albicans confers azole resistance.
Wu Y; Gao N; Li C; Gao J; Ying C
FEMS Yeast Res; 2017 May; 17(3):. PubMed ID: 28334124
[TBL] [Abstract][Full Text] [Related]
29. Formation of azole-resistant Candida albicans by mutation of sterol 14-demethylase P450.
Asai K; Tsuchimori N; Okonogi K; Perfect JR; Gotoh O; Yoshida Y
Antimicrob Agents Chemother; 1999 May; 43(5):1163-9. PubMed ID: 10223930
[TBL] [Abstract][Full Text] [Related]
30. Activity of Isavuconazole and Other Azoles against Candida Clinical Isolates and Yeast Model Systems with Known Azole Resistance Mechanisms.
Sanglard D; Coste AT
Antimicrob Agents Chemother; 2016 Jan; 60(1):229-38. PubMed ID: 26482310
[TBL] [Abstract][Full Text] [Related]
31. Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility.
Mellado E; Garcia-Effron G; Buitrago MJ; Alcazar-Fuoli L; Cuenca-Estrella M; Rodriguez-Tudela JL
Antimicrob Agents Chemother; 2005 Jun; 49(6):2536-8. PubMed ID: 15917566
[TBL] [Abstract][Full Text] [Related]
32. Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase.
Sagatova AA; Keniya MV; Wilson RK; Monk BC; Tyndall JD
Antimicrob Agents Chemother; 2015 Aug; 59(8):4982-9. PubMed ID: 26055382
[TBL] [Abstract][Full Text] [Related]
33. The amino acid substitution N136Y in Candida albicans sterol 14alpha-demethylase is involved in fluconazole resistance.
Alvarez-Rueda N; Fleury A; Logé C; Pagniez F; Robert E; Morio F; Le Pape P
Med Mycol; 2016 Oct; 54(7):764-775. PubMed ID: 27143634
[TBL] [Abstract][Full Text] [Related]
34. Fluconazole binding and sterol demethylation in three CYP51 isoforms indicate differences in active site topology.
Bellamine A; Lepesheva GI; Waterman MR
J Lipid Res; 2004 Nov; 45(11):2000-7. PubMed ID: 15314102
[TBL] [Abstract][Full Text] [Related]
35. Contributions of both ATP-Binding Cassette Transporter and Cyp51A Proteins Are Essential for Azole Resistance in Aspergillus fumigatus.
Paul S; Diekema D; Moye-Rowley WS
Antimicrob Agents Chemother; 2017 May; 61(5):. PubMed ID: 28264842
[TBL] [Abstract][Full Text] [Related]
36. Aspergillus fumigatus harbouring the sole Y121F mutation shows decreased susceptibility to voriconazole but maintained susceptibility to itraconazole and posaconazole.
Lescar J; Meyer I; Akshita K; Srinivasaraghavan K; Verma C; Palous M; Mazier D; Datry A; Fekkar A
J Antimicrob Chemother; 2014 Dec; 69(12):3244-7. PubMed ID: 25125676
[TBL] [Abstract][Full Text] [Related]
37. Surveillance for azole resistance in clinical and environmental isolates of Aspergillus fumigatus in Australia and cyp51A homology modelling of azole-resistant isolates.
Talbot JJ; Subedi S; Halliday CL; Hibbs DE; Lai F; Lopez-Ruiz FJ; Harper L; Park RF; Cuddy WS; Biswas C; Cooley L; Carter D; Sorrell TC; Barrs VR; Chen SC
J Antimicrob Chemother; 2018 Sep; 73(9):2347-2351. PubMed ID: 29846581
[TBL] [Abstract][Full Text] [Related]
38. The clinical candidate VT-1161 is a highly potent inhibitor of Candida albicans CYP51 but fails to bind the human enzyme.
Warrilow AG; Hull CM; Parker JE; Garvey EP; Hoekstra WJ; Moore WR; Schotzinger RJ; Kelly DE; Kelly SL
Antimicrob Agents Chemother; 2014 Dec; 58(12):7121-7. PubMed ID: 25224009
[TBL] [Abstract][Full Text] [Related]
39. Simulations of CYP51A from Aspergillus fumigatus in a model bilayer provide insights into triazole drug resistance.
Nash A; Rhodes J
Med Mycol; 2018 Apr; 56(3):361-373. PubMed ID: 28992260
[TBL] [Abstract][Full Text] [Related]
40. New Insights into the Cyp51 Contribution to Azole Resistance in
Pérez-Cantero A; López-Fernández L; Guarro J; Capilla J
Antimicrob Agents Chemother; 2019 Jul; 63(7):. PubMed ID: 31061160
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
