These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 1474395)

  • 1. Automatic superposition of drug molecules based on their common receptor site.
    Kato Y; Inoue A; Yamada M; Tomioka N; Itai A
    J Comput Aided Mol Des; 1992 Oct; 6(5):475-86. PubMed ID: 1474395
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A receptor model for tumor promoters: rational superposition of teleocidins and phorbol esters.
    Itai A; Kato Y; Tomioka N; Iitaka Y; Endo Y; Hasegawa M; Shudo K; Fujiki H; Sakai S
    Proc Natl Acad Sci U S A; 1988 Jun; 85(11):3688-92. PubMed ID: 3131760
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of hydrogen-bonds in drug binding.
    Wade RC; Goodford PJ
    Prog Clin Biol Res; 1989; 289():433-44. PubMed ID: 2726808
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An automated method for predicting the positions of hydrogen-bonding atoms in binding sites.
    Mills JE; Perkins TD; Dean PM
    J Comput Aided Mol Des; 1997 May; 11(3):229-42. PubMed ID: 9263850
    [TBL] [Abstract][Full Text] [Related]  

  • 5. KEY, LOCK, and LOCKSMITH: complementary hydropathic map predictions of drug structure from a known receptor-receptor structure from known drugs.
    Kellogg GE; Abraham DJ
    J Mol Graph; 1992 Dec; 10(4):212-7, 226. PubMed ID: 1476993
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular electrostatic potential as a factor of drug-receptor recognition.
    Dukhovich FS; Darkhovskii MB
    J Mol Recognit; 2003; 16(4):191-202. PubMed ID: 12898669
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The role and significance of unconventional hydrogen bonds in small molecule recognition by biological receptors of pharmaceutical relevance.
    Tóth G; Bowers SG; Truong AP; Probst G
    Curr Pharm Des; 2007; 13(34):3476-93. PubMed ID: 18220785
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Do enthalpy and entropy distinguish first in class from best in class?
    Freire E
    Drug Discov Today; 2008 Oct; 13(19-20):869-74. PubMed ID: 18703160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacophore modelling: a forty year old approach and its modern synergies.
    Caporuscio F; Tafi A
    Curr Med Chem; 2011; 18(17):2543-53. PubMed ID: 21568893
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 3DFS: a new 3D flexible searching system for use in drug design.
    Wang T; Zhou J
    J Chem Inf Comput Sci; 1998; 38(1):71-7. PubMed ID: 9461644
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rational automatic search method for stable docking models of protein and ligand.
    Mizutani MY; Tomioka N; Itai A
    J Mol Biol; 1994 Oct; 243(2):310-26. PubMed ID: 7932757
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deterministic pharmacophore detection via multiple flexible alignment of drug-like molecules.
    Schneidman-Duhovny D; Dror O; Inbar Y; Nussinov R; Wolfson HJ
    J Comput Biol; 2008 Sep; 15(7):737-54. PubMed ID: 18662104
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An exploration of a novel strategy for superposing several flexible molecules.
    Perkins TD; Dean PM
    J Comput Aided Mol Des; 1993 Apr; 7(2):155-72. PubMed ID: 8320554
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The slope parameter and the receptor reserve.
    Giraldo J
    Trends Pharmacol Sci; 1998 Nov; 19(11):445; Discussion 445-6. PubMed ID: 9850607
    [No Abstract]   [Full Text] [Related]  

  • 15. Receptor-based pharmacophore tool for design and development of next-generation drugs.
    Udayakumar M; Kumar PS; Hemavathi K; Shanmugapriya P; Seenivasagam R
    Int J Bioinform Res Appl; 2013; 9(5):487-516. PubMed ID: 24001724
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High content pharmacophores from molecular fields: a biologically relevant method for comparing and understanding ligands.
    Cheeseright TJ; Mackey MD; Scoffin RA
    Curr Comput Aided Drug Des; 2011 Sep; 7(3):190-205. PubMed ID: 21726191
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intramolecular hydrogen bonding in medicinal chemistry.
    Kuhn B; Mohr P; Stahl M
    J Med Chem; 2010 Mar; 53(6):2601-11. PubMed ID: 20175530
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IADE: a system for intelligent automatic design of bioisosteric analogs.
    Ertl P; Lewis R
    J Comput Aided Mol Des; 2012 Nov; 26(11):1207-15. PubMed ID: 23053736
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular modeling of sigma 1 receptor ligands: a model of binding conformational and electrostatic considerations.
    Gund TM; Floyd J; Jung D
    J Mol Graph Model; 2004 Jan; 22(3):221-30. PubMed ID: 14629980
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Shape-Based Generative Modeling for de Novo Drug Design.
    Skalic M; Jiménez J; Sabbadin D; De Fabritiis G
    J Chem Inf Model; 2019 Mar; 59(3):1205-1214. PubMed ID: 30762364
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.