BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

363 related articles for article (PubMed ID: 14754412)

  • 1. Structure of multidrug-resistance proteins of the ATP-binding cassette (ABC) superfamily.
    Altenberg GA
    Curr Med Chem Anticancer Agents; 2004 Jan; 4(1):53-62. PubMed ID: 14754412
    [TBL] [Abstract][Full Text] [Related]  

  • 2. P-glycoprotein-mediated resistance to chemotherapy in cancer cells: using recombinant cytosolic domains to establish structure-function relationships.
    Di Pietro A; Dayan G; Conseil G; Steinfels E; Krell T; Trompier D; Baubichon-Cortay H; Jault J
    Braz J Med Biol Res; 1999 Aug; 32(8):925-39. PubMed ID: 10454753
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATP-induced conformational changes of nucleotide-binding domains in an ABC transporter. Importance of the water-mediated entropic force.
    Hayashi T; Chiba S; Kaneta Y; Furuta T; Sakurai M
    J Phys Chem B; 2014 Nov; 118(44):12612-20. PubMed ID: 25302667
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR).
    Teodori E; Dei S; Martelli C; Scapecchi S; Gualtieri F
    Curr Drug Targets; 2006 Jul; 7(7):893-909. PubMed ID: 16842220
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multidrug resistance ABC transporters.
    Chang G
    FEBS Lett; 2003 Nov; 555(1):102-5. PubMed ID: 14630327
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conformational coupling of the nucleotide-binding and the transmembrane domains in ABC transporters.
    Wen PC; Tajkhorshid E
    Biophys J; 2011 Aug; 101(3):680-90. PubMed ID: 21806936
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of the breast cancer resistance protein (ABCG2) in drug transport.
    Mao Q; Unadkat JD
    AAPS J; 2005 May; 7(1):E118-33. PubMed ID: 16146333
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of ABC transporters: a molecular dynamics simulation of a well characterized nucleotide-binding subunit.
    Jones PM; George AM
    Proc Natl Acad Sci U S A; 2002 Oct; 99(20):12639-44. PubMed ID: 12237398
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Substrate-induced conformational changes in the nucleotide-binding domains of lipid bilayer-associated P-glycoprotein during ATP hydrolysis.
    Zoghbi ME; Mok L; Swartz DJ; Singh A; Fendley GA; Urbatsch IL; Altenberg GA
    J Biol Chem; 2017 Dec; 292(50):20412-20424. PubMed ID: 29018094
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2.
    Shukla S; Robey RW; Bates SE; Ambudkar SV
    Drug Metab Dispos; 2009 Feb; 37(2):359-65. PubMed ID: 18971320
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cysteine-scanning mutagenesis provides no evidence for the extracellular accessibility of the nucleotide-binding domains of the multidrug resistance transporter P-glycoprotein.
    Blott EJ; Higgins CF; Linton KJ
    EMBO J; 1999 Dec; 18(23):6800-8. PubMed ID: 10581253
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New light on multidrug binding by an ATP-binding-cassette transporter.
    Shilling RA; Venter H; Velamakanni S; Bapna A; Woebking B; Shahi S; van Veen HW
    Trends Pharmacol Sci; 2006 Apr; 27(4):195-203. PubMed ID: 16545467
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting Nucleotide Binding Domain of Multidrug Resistance-associated Protein-1 (MRP1) for the Reversal of Multi Drug Resistance in Cancer.
    Dhasmana D; Singh A; Shukla R; Tripathi T; Garg N
    Sci Rep; 2018 Aug; 8(1):11973. PubMed ID: 30097643
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs.
    Badiee SA; Isu UH; Khodadadi E; Moradi M
    Membranes (Basel); 2023 May; 13(6):. PubMed ID: 37367772
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2.
    Dai CL; Tiwari AK; Wu CP; Su XD; Wang SR; Liu DG; Ashby CR; Huang Y; Robey RW; Liang YJ; Chen LM; Shi CJ; Ambudkar SV; Chen ZS; Fu LW
    Cancer Res; 2008 Oct; 68(19):7905-14. PubMed ID: 18829547
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multidrug resistance in cancer chemotherapy and xenobiotic protection mediated by the half ATP-binding cassette transporter ABCG2.
    Han B; Zhang JT
    Curr Med Chem Anticancer Agents; 2004 Jan; 4(1):31-42. PubMed ID: 14754410
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multidrug resistance-associated protein: a protein distinct from P-glycoprotein involved in cytotoxic drug expulsion.
    Barrand MA; Bagrij T; Neo SY
    Gen Pharmacol; 1997 May; 28(5):639-45. PubMed ID: 9184795
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis.
    Rosenberg MF; Mao Q; Holzenburg A; Ford RC; Deeley RG; Cole SP
    J Biol Chem; 2001 May; 276(19):16076-82. PubMed ID: 11279022
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of multidrug resistance-linked P-glycoprotein (ABCB1) function by 5'-fluorosulfonylbenzoyl 5'-adenosine: evidence for an ATP analogue that interacts with both drug-substrate-and nucleotide-binding sites.
    Ohnuma S; Chufan E; Nandigama K; Jenkins LM; Durell SR; Appella E; Sauna ZE; Ambudkar SV
    Biochemistry; 2011 May; 50(18):3724-35. PubMed ID: 21452853
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multidrug resistance: molecular mechanisms and clinical relevance.
    Ling V
    Cancer Chemother Pharmacol; 1997; 40 Suppl():S3-8. PubMed ID: 9272126
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.