BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 14756243)

  • 1. Cathepsins in the osteoclast.
    Goto T; Yamaza T; Tanaka T
    J Electron Microsc (Tokyo); 2003; 52(6):551-8. PubMed ID: 14756243
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Osteoclastic bone degradation and the role of different cysteine proteinases and matrix metalloproteinases: differences between calvaria and long bone.
    Everts V; Korper W; Hoeben KA; Jansen ID; Bromme D; Cleutjens KB; Heeneman S; Peters C; Reinheckel T; Saftig P; Beertsen W
    J Bone Miner Res; 2006 Sep; 21(9):1399-408. PubMed ID: 16939398
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Degradation of the organic phase of bone by osteoclasts: a secondary role for lysosomal acidification.
    Henriksen K; Sørensen MG; Nielsen RH; Gram J; Schaller S; Dziegiel MH; Everts V; Bollerslev J; Karsdal MA
    J Bone Miner Res; 2006 Jan; 21(1):58-66. PubMed ID: 16355274
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Matrix metalloproteinases (MMP) and cathepsin K contribute differently to osteoclastic activities.
    Delaissé JM; Andersen TL; Engsig MT; Henriksen K; Troen T; Blavier L
    Microsc Res Tech; 2003 Aug; 61(6):504-13. PubMed ID: 12879418
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functions of cathepsin K in bone resorption. Lessons from cathepsin K deficient mice.
    Saftig P; Hunziker E; Everts V; Jones S; Boyde A; Wehmeyer O; Suter A; von Figura K
    Adv Exp Med Biol; 2000; 477():293-303. PubMed ID: 10849757
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Localization of rat cathepsin K in osteoclasts and resorption pits: inhibition of bone resorption and cathepsin K-activity by peptidyl vinyl sulfones.
    Xia L; Kilb J; Wex H; Li Z; Lipyansky A; Breuil V; Stein L; Palmer JT; Dempster DW; Brömme D
    Biol Chem; 1999 Jun; 380(6):679-87. PubMed ID: 10430032
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cystatin B as an intracellular modulator of bone resorption.
    Laitala-Leinonen T; Rinne R; Saukko P; Väänänen HK; Rinne A
    Matrix Biol; 2006 Apr; 25(3):149-57. PubMed ID: 16321512
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantification of the expression levels of lysosomal cysteine proteinases in purified human osteoclastic cells by competitive RT-PCR.
    Ishibashi O; Inui T; Mori Y; Kurokawa T; Kokubo T; Kumegawa M
    Calcif Tissue Int; 2001 Feb; 68(2):109-16. PubMed ID: 11310346
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intracellular machinery for matrix degradation in bone-resorbing osteoclasts.
    Vääräniemi J; Halleen JM; Kaarlonen K; Ylipahkala H; Alatalo SL; Andersson G; Kaija H; Vihko P; Väänänen HK
    J Bone Miner Res; 2004 Sep; 19(9):1432-40. PubMed ID: 15312243
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impaired bone resorption in cathepsin K-deficient mice is partially compensated for by enhanced osteoclastogenesis and increased expression of other proteases via an increased RANKL/OPG ratio.
    Kiviranta R; Morko J; Alatalo SL; NicAmhlaoibh R; Risteli J; Laitala-Leinonen T; Vuorio E
    Bone; 2005 Jan; 36(1):159-72. PubMed ID: 15664014
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Different cysteine proteinases involved in bone resorption and osteoclast formation.
    Brage M; Abrahamson M; Lindström V; Grubb A; Lerner UH
    Calcif Tissue Int; 2005 Jun; 76(6):439-47. PubMed ID: 15906014
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts.
    Fuller K; Lawrence KM; Ross JL; Grabowska UB; Shiroo M; Samuelsson B; Chambers TJ
    Bone; 2008 Jan; 42(1):200-11. PubMed ID: 17962093
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Estrogen reduces the depth of resorption pits by disturbing the organic bone matrix degradation activity of mature osteoclasts.
    Parikka V; Lehenkari P; Sassi ML; Halleen J; Risteli J; Härkönen P; Väänänen HK
    Endocrinology; 2001 Dec; 142(12):5371-8. PubMed ID: 11713237
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption.
    Wilson SR; Peters C; Saftig P; Brömme D
    J Biol Chem; 2009 Jan; 284(4):2584-92. PubMed ID: 19028686
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Erosive arthritis in a patient with pycnodysostosis: an experiment of nature.
    Ainola M; Valleala H; Nykänen P; Risteli J; Hanemaaijer R; Konttinen YT
    Arthritis Rheum; 2008 Nov; 58(11):3394-401. PubMed ID: 18975331
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A potent small molecule, nonpeptide inhibitor of cathepsin K (SB 331750) prevents bone matrix resorption in the ovariectomized rat.
    Lark MW; Stroup GB; James IE; Dodds RA; Hwang SM; Blake SM; Lechowska BA; Hoffman SJ; Smith BR; Kapadia R; Liang X; Erhard K; Ru Y; Dong X; Marquis RW; Veber D; Gowen M
    Bone; 2002 May; 30(5):746-53. PubMed ID: 11996914
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice.
    Saftig P; Hunziker E; Wehmeyer O; Jones S; Boyde A; Rommerskirch W; Moritz JD; Schu P; von Figura K
    Proc Natl Acad Sci U S A; 1998 Nov; 95(23):13453-8. PubMed ID: 9811821
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional heterogeneity of osteoclasts: matrix metalloproteinases participate in osteoclastic resorption of calvarial bone but not in resorption of long bone.
    Everts V; Korper W; Jansen DC; Steinfort J; Lammerse I; Heera S; Docherty AJ; Beertsen W
    FASEB J; 1999 Jul; 13(10):1219-30. PubMed ID: 10385612
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potent and selective inhibition of human cathepsin K leads to inhibition of bone resorption in vivo in a nonhuman primate.
    Stroup GB; Lark MW; Veber DF; Bhattacharyya A; Blake S; Dare LC; Erhard KF; Hoffman SJ; James IE; Marquis RW; Ru Y; Vasko-Moser JA; Smith BR; Tomaszek T; Gowen M
    J Bone Miner Res; 2001 Oct; 16(10):1739-46. PubMed ID: 11585335
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Overexpression of cathepsin K accelerates the resorption cycle and osteoblast differentiation in vitro.
    Morko J; Kiviranta R; Mulari MT; Ivaska KK; Väänänen HK; Vuorio E; Laitala-Leinonen T
    Bone; 2009 Apr; 44(4):717-28. PubMed ID: 19118660
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.