BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

290 related articles for article (PubMed ID: 14757177)

  • 1. Regulation of inosine monophosphate dehydrogenase type I and type II isoforms in human lymphocytes.
    Jain J; Almquist SJ; Ford PJ; Shlyakhter D; Wang Y; Nimmesgern E; Germann UA
    Biochem Pharmacol; 2004 Feb; 67(4):767-76. PubMed ID: 14757177
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of mycophenolic acid on inosine monophosphate dehydrogenase I and II mRNA expression in white blood cells and various tissues in sheep.
    Dzidic A; Prgomet C; Mohr A; Meyer K; Bauer J; Meyer HH; Pfaffl MW
    J Vet Med A Physiol Pathol Clin Med; 2006 May; 53(4):163-9. PubMed ID: 16629948
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of pharmacological efficacy of VX-148, a new, potent immunosuppressive inosine 5'-monophosphate dehydrogenase inhibitor.
    Jain J; Almquist SJ; Heiser AD; Shlyakhter D; Leon E; Memmott C; Moody CS; Nimmesgern E; Decker C
    J Pharmacol Exp Ther; 2002 Sep; 302(3):1272-7. PubMed ID: 12183689
    [TBL] [Abstract][Full Text] [Related]  

  • 4. VX-497: a novel, selective IMPDH inhibitor and immunosuppressive agent.
    Jain J; Almquist SJ; Shlyakhter D; Harding MW
    J Pharm Sci; 2001 May; 90(5):625-37. PubMed ID: 11288107
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective inhibition of human Molt-4 leukemia type II inosine 5'-monophosphate dehydrogenase by the 1,5-diazabicyclo[3.1.0]hexane-2,4-diones.
    Barnes BJ; Eakin AE; Izydore RA; Hall IH
    Biochemistry; 2000 Nov; 39(45):13641-50. PubMed ID: 11076502
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase and differentiation induction of K562 cells among the mycophenolic acid derivatives.
    Mitsuhashi S; Takenaka J; Iwamori K; Nakajima N; Ubukata M
    Bioorg Med Chem; 2010 Nov; 18(22):8106-11. PubMed ID: 20934342
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inosine monophosphate dehydrogenase variability in renal transplant patients on long-term mycophenolate mofetil therapy.
    Chiarelli LR; Molinaro M; Libetta C; Tinelli C; Cosmai L; Valentini G; Dal Canton A; Regazzi M
    Br J Clin Pharmacol; 2010 Jan; 69(1):38-50. PubMed ID: 20078611
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of human T lymphocyte activation on inosine monophosphate dehydrogenase expression.
    Dayton JS; Lindsten T; Thompson CB; Mitchell BS
    J Immunol; 1994 Feb; 152(3):984-91. PubMed ID: 7905505
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The structure of inosine 5'-monophosphate dehydrogenase and the design of novel inhibitors.
    Sintchak MD; Nimmesgern E
    Immunopharmacology; 2000 May; 47(2-3):163-84. PubMed ID: 10878288
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and biological evaluation of novel inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitors.
    Dunkern T; Chavan S; Bankar D; Patil A; Kulkarni P; Kharkar PS; Prabhu A; Goebel H; Rolser E; Burckhard-Boer W; Arumugam P; Makhija MT
    J Enzyme Inhib Med Chem; 2014 Jun; 29(3):408-19. PubMed ID: 23663081
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.
    Zhou S; Liu R; Baroudy BM; Malcolm BA; Reyes GR
    Virology; 2003 Jun; 310(2):333-42. PubMed ID: 12781720
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inosine-5'-monophosphate dehydrogenase: regulation of expression and role in cellular proliferation and T lymphocyte activation.
    Zimmermann AG; Gu JJ; Laliberté J; Mitchell BS
    Prog Nucleic Acid Res Mol Biol; 1998; 61():181-209. PubMed ID: 9752721
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon.
    Markland W; McQuaid TJ; Jain J; Kwong AD
    Antimicrob Agents Chemother; 2000 Apr; 44(4):859-66. PubMed ID: 10722482
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inosine-5'-monophosphate dehydrogenase is required for mitogenic competence of transformed pancreatic beta cells.
    Metz S; Holland S; Johnson L; Espling E; Rabaglia M; Segu V; Brockenbrough JS; Tran PO
    Endocrinology; 2001 Jan; 142(1):193-204. PubMed ID: 11145582
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inosine monophosphate dehydrogenase activity in paediatrics: age-related regulation and response to mycophenolic acid.
    Rother A; Glander P; Vitt E; Czock D; von Ahsen N; Armstrong VW; Oellerich M; Budde K; Feneberg R; Tönshoff B; Weber LT
    Eur J Clin Pharmacol; 2012 Jun; 68(6):913-22. PubMed ID: 22274404
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Plasma and intracellular pharmacokinetic-pharmacodynamic analysis of mycophenolic acid in de novo kidney transplant patients.
    Thi MT; Mourad M; Capron A; Tshinanu FM; Vincent MF; Wallemacq P
    Clin Biochem; 2015 Apr; 48(6):401-5. PubMed ID: 25523299
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic Acid by GTP.
    Ji Y; Gu J; Makhov AM; Griffith JD; Mitchell BS
    J Biol Chem; 2006 Jan; 281(1):206-12. PubMed ID: 16243838
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Species-specific inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid.
    Digits JA; Hedstrom L
    Biochemistry; 1999 Nov; 38(46):15388-97. PubMed ID: 10563825
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of IMPDH1 is regulated in response to mycophenolate concentration.
    Bremer S; Vethe NT; Rootwelt H; Bergan S
    Int Immunopharmacol; 2009 Feb; 9(2):173-80. PubMed ID: 19010451
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Guanine nucleotide depletion inhibits pre-ribosomal RNA synthesis and causes nucleolar disruption.
    Huang M; Ji Y; Itahana K; Zhang Y; Mitchell B
    Leuk Res; 2008 Jan; 32(1):131-41. PubMed ID: 17462731
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.