1181 related articles for article (PubMed ID: 14761187)
21. Discovery of 4-(benzylaminomethylene)isoquinoline-1,3-(2H,4H)-diones and 4-[(pyridylmethyl)aminomethylene]isoquinoline-1,3-(2H,4H)-diones as potent and selective inhibitors of the cyclin-dependent kinase 4.
Tsou HR; Liu X; Birnberg G; Kaplan J; Otteng M; Tran T; Kutterer K; Tang Z; Suayan R; Zask A; Ravi M; Bretz A; Grillo M; McGinnis JP; Rabindran SK; Ayral-Kaloustian S; Mansour TS
J Med Chem; 2009 Apr; 52(8):2289-310. PubMed ID: 19317452
[TBL] [Abstract][Full Text] [Related]
22. Rational design, synthesis, and biological evaluation of bis(pyrimido[5,6,1-de]acridines) and bis(pyrazolo[3,4,5-kl]acridine-5-carboxamides) as new anticancer agents.
Antonini I; Polucci P; Magnano A; Sparapani S; Martelli S
J Med Chem; 2004 Oct; 47(21):5244-50. PubMed ID: 15456268
[TBL] [Abstract][Full Text] [Related]
23. Novel DNA intercalators without basic side chains as efficient antitumor agents: design, synthesis and evaluation of benzo-[c,d]-indol-malononitrile derivatives.
Li X; Wang Q; Qing Y; Lin Y; Zhang Y; Qian X; Cui J
Bioorg Med Chem; 2010 May; 18(9):3279-84. PubMed ID: 20385497
[TBL] [Abstract][Full Text] [Related]
24. Design, synthesis, and biological evaluation of cytotoxic 11-alkenylindenoisoquinoline topoisomerase I inhibitors and indenoisoquinoline-camptothecin hybrids.
Fox BM; Xiao X; Antony S; Kohlhagen G; Pommier Y; Staker BL; Stewart L; Cushman M
J Med Chem; 2003 Jul; 46(15):3275-82. PubMed ID: 12852757
[TBL] [Abstract][Full Text] [Related]
25. Evaluation of anticancer effects of newly synthesized dihydropyridine derivatives in comparison to verapamil and doxorubicin on T47D parental and resistant cell lines in vitro.
Bazargan L; Fouladdel S; Shafiee A; Amini M; Ghaffari SM; Azizi E
Cell Biol Toxicol; 2008 Apr; 24(2):165-74. PubMed ID: 17805981
[TBL] [Abstract][Full Text] [Related]
26. DNA binding ellipticine analogues: synthesis, biological evaluation, and structure-activity relationships.
Ferlin MG; Marzano C; Gandin V; Dall'Acqua S; Dalla Via L
ChemMedChem; 2009 Mar; 4(3):363-77. PubMed ID: 19197924
[TBL] [Abstract][Full Text] [Related]
27. Structure-activity relationships for substituted bis(acridine-4-carboxamides): a new class of anticancer agents.
Gamage SA; Spicer JA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
J Med Chem; 1999 Jul; 42(13):2383-93. PubMed ID: 10395479
[TBL] [Abstract][Full Text] [Related]
28. Design, synthesis and structure-activity relationships of antiproliferative 1,3-disubstituted urea derivatives.
Li HQ; Zhu TT; Yan T; Luo Y; Zhu HL
Eur J Med Chem; 2009 Feb; 44(2):453-9. PubMed ID: 18514972
[TBL] [Abstract][Full Text] [Related]
29. The structure-based design, synthesis, and biological evaluation of DNA-binding amide linked bisintercalating bisanthrapyrazole anticancer compounds.
Hasinoff BB; Zhang R; Wu X; Guziec LJ; Guziec FS; Marshall K; Yalowich JC
Bioorg Med Chem; 2009 Jul; 17(13):4575-82. PubMed ID: 19457675
[TBL] [Abstract][Full Text] [Related]
30. Synthesis, X-ray crystal structures, stabilities, and in vitro cytotoxic activities of new heteroarylacrylonitriles.
Saczewski F; Reszka P; Gdaniec M; Grünert R; Bednarski PJ
J Med Chem; 2004 Jun; 47(13):3438-49. PubMed ID: 15189040
[TBL] [Abstract][Full Text] [Related]
31. Synthesis and biological evaluation of 2,4-diamino-6-(arylaminomethyl)pyrido[2,3-d]pyrimidines as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase and as antiopportunistic infection and antitumor agents.
Gangjee A; Adair OO; Queener SF
J Med Chem; 2003 Nov; 46(23):5074-82. PubMed ID: 14584957
[TBL] [Abstract][Full Text] [Related]
32. Synthesis, structure elucidation and identification of antitumoural properties of novel fused 1,2,4-triazine aryl derivatives.
Sztanke K; Pasternak K; Rzymowska J; Sztanke M; Kandefer-Szerszeń M
Eur J Med Chem; 2008 May; 43(5):1085-94. PubMed ID: 17868955
[TBL] [Abstract][Full Text] [Related]
33. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
Romagnoli R; Baraldi PG; Pavani MG; Tabrizi MA; Preti D; Fruttarolo F; Piccagli L; Jung MK; Hamel E; Borgatti M; Gambari R
J Med Chem; 2006 Jun; 49(13):3906-15. PubMed ID: 16789746
[TBL] [Abstract][Full Text] [Related]
34. Platinum(II) compounds with chelating ligands based on pyridine and pyrimidine: synthesis, characterizations, DFT calculations, cytotoxic assays and binding to a DNA model base.
Roy S; Westmaas JA; Buda F; Reedijk J
J Inorg Biochem; 2009 Sep; 103(9):1278-87. PubMed ID: 19656572
[TBL] [Abstract][Full Text] [Related]
35. Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: various DNA binding geometry and interesting antitumor capacity.
Zhang Z; Yang Y; Zhang D; Wang Y; Qian X; Liu F
Bioorg Med Chem; 2006 Oct; 14(20):6962-70. PubMed ID: 16828559
[TBL] [Abstract][Full Text] [Related]
36. Synthesis, photochemical synthesis, DNA binding and antitumor evaluation of novel cyano- and amidino-substituted derivatives of naphtho-furans, naphtho-thiophenes, thieno-benzofurans, benzo-dithiophenes and their acyclic precursors.
Starcević K; Kralj M; Piantanida I; Suman L; Pavelić K; Karminski-Zamola G
Eur J Med Chem; 2006 Aug; 41(8):925-39. PubMed ID: 16650510
[TBL] [Abstract][Full Text] [Related]
37. Synthesis of nitrated indenoisoquinolines as topoisomerase I inhibitors.
Morrell A; Antony S; Kohlhagen G; Pommier Y; Cushman M
Bioorg Med Chem Lett; 2004 Jul; 14(14):3659-63. PubMed ID: 15203138
[TBL] [Abstract][Full Text] [Related]
38. Novel autoxidative cleavage reaction of 9-fluoredenes discovered during synthesis of a potential DNA-threading indenoisoquinoline.
Xiao X; Antony S; Kohlhagen G; Pommier Y; Cushman M
J Org Chem; 2004 Oct; 69(22):7495-501. PubMed ID: 15497974
[TBL] [Abstract][Full Text] [Related]
39. Activity of nitrogen-containing and non-nitrogen-containing bisphosphonates on tumor cell lines.
Zhang Y; Leon A; Song Y; Studer D; Haase C; Koscielski LA; Oldfield E
J Med Chem; 2006 Sep; 49(19):5804-14. PubMed ID: 16970405
[TBL] [Abstract][Full Text] [Related]
40. A facile synthesis and biological activity of novel tetrahydrobenzo[4',5']thieno[3',2':5,6]pyrido[4,3-d]pyrimidin-4(3H)-ones.
Ren Q; Liang YJ; He H; Fu L; Gu Y
Bioorg Med Chem Lett; 2009 Dec; 19(23):6713-6. PubMed ID: 19846302
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]