These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

454 related articles for article (PubMed ID: 14761194)

  • 1. Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant.
    Ragno R; Mai A; Sbardella G; Artico M; Massa S; Musiu C; Mura M; Marturana F; Cadeddu A; La Colla P
    J Med Chem; 2004 Feb; 47(4):928-34. PubMed ID: 14761194
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains.
    Mai A; Artico M; Rotili D; Tarantino D; Clotet-Codina I; Armand-Ugón M; Ragno R; Simeoni S; Sbardella G; Nawrozkij MB; Samuele A; Maga G; Esté JA
    J Med Chem; 2007 Nov; 50(22):5412-24. PubMed ID: 17910429
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.
    Mai A; Artico M; Ragno R; Sbardella G; Massa S; Musiu C; Mura M; Marturana F; Cadeddu A; Maga G; La Colla P
    Bioorg Med Chem; 2005 Mar; 13(6):2065-77. PubMed ID: 15727860
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Mai A; Sbardella G; Artico M; Ragno R; Massa S; Novellino E; Greco G; Lavecchia A; Musiu C; La Colla M; Murgioni C; La Colla P; Loddo R
    J Med Chem; 2001 Aug; 44(16):2544-54. PubMed ID: 11472208
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4(3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives.
    Mai A; Artico M; Sbardella G; Massa S; Novellino E; Greco G; Loi AG; Tramontano E; Marongiu ME; La Colla P
    J Med Chem; 1999 Feb; 42(4):619-27. PubMed ID: 10052969
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives.
    Ranise A; Spallarossa A; Cesarini S; Bondavalli F; Schenone S; Bruno O; Menozzi G; Fossa P; Mosti L; La Colla M; Sanna G; Murreddu M; Collu G; Busonera B; Marongiu ME; Pani A; La Colla P; Loddo R
    J Med Chem; 2005 Jun; 48(11):3858-73. PubMed ID: 15916438
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Non-nucleoside HIV reverse transcriptase inhibitors, Part 6[1]: synthesis and anti-HIV activity of novel 2-[(arylcarbonylmethyl)thio]-6-arylthio DABO analogues.
    Sun GF; Kuang YY; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    Arch Pharm (Weinheim); 2005 Oct; 338(10):457-61. PubMed ID: 16211654
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of 6-substituted 5-alkyl-2-(phenylaminocarbonylmethylthio)pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs.
    Yu M; Li Z; Liu S; Fan E; Pannecouque C; De Clercq E; Liu X
    ChemMedChem; 2011 May; 6(5):826-33. PubMed ID: 21322110
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and anti-HIV-1 activity evaluation of 5-alkyl-2-alkylthio-6-(arylcarbonyl or alpha-cyanoarylmethyl)-3,4-dihydropyrimidin-4(3H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Ji L; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    J Med Chem; 2007 Apr; 50(8):1778-86. PubMed ID: 17381078
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5-Alkyl-2-[(aryl and alkyloxylcarbonylmethyl)thio]-6-(1-naphthylmethyl) pyrimidin-4(3H)-ones as an unique HIV reverse transcriptase inhibitors of S-DABO series.
    He Y; Chen F; Sun G; Wang Y; De Clercq E; Balzarini J; Pannecouque C
    Bioorg Med Chem Lett; 2004 Jun; 14(12):3173-6. PubMed ID: 15149669
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Zhang J; Zhan P; Wu J; Li Z; Jiang Y; Ge W; Pannecouque C; De Clercq E; Liu X
    Bioorg Med Chem; 2011 Jul; 19(14):4366-76. PubMed ID: 21683601
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: novel non-nucleoside reverse transcriptase inhibitors of the S-DABO series.
    Mai A; Artico M; Sbardella G; Quartarone S; Massa S; Loi AG; De Montis A; Scintu F; Putzolu M; La Colla P
    J Med Chem; 1997 May; 40(10):1447-54. PubMed ID: 9154967
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and in vitro anti-HIV evaluation of a new series of 6-arylmethyl-substituted S-DABOs as potential non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Wang YP; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    Eur J Med Chem; 2009 Mar; 44(3):1016-23. PubMed ID: 18692274
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs.
    Radi M; Falciani C; Contemori L; Petricci E; Maga G; Samuele A; Zanoli S; Terrazas M; Castria M; Togninelli A; Esté JA; Clotet-Codina I; Armand-Ugón M; Botta M
    ChemMedChem; 2008 Apr; 3(4):573-93. PubMed ID: 18081133
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity.
    Manetti F; Esté JA; Clotet-Codina I; Armand-Ugón M; Maga G; Crespan E; Cancio R; Mugnaini C; Bernardini C; Togninelli A; Carmi C; Alongi M; Petricci E; Massa S; Corelli F; Botta M
    J Med Chem; 2005 Dec; 48(25):8000-8. PubMed ID: 16335924
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of novel C5 halogen-functionalized S-DABO as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Qin H; Liu C; Guo Y; Wang R; Zhang J; Ma L; Zhang Z; Wang X; Cui Y; Liu J
    Bioorg Med Chem; 2010 May; 18(9):3231-7. PubMed ID: 20371182
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nonnucleoside HIV-1 reverse transcriptase inhibitors; part 3. Synthesis and antiviral activity of 5-alkyl-2-[(aryl and alkyloxyl-carbonylmethyl)thio]-6-(1-naphthylmethyl) pyrimidin-4(3H)-ones.
    He Y; Chen F; Yu X; Wang Y; De Clercq E; Balzarini J; Pannecouque C
    Bioorg Chem; 2004 Dec; 32(6):536-48. PubMed ID: 15530994
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 4-Benzyl and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones: in vitro evaluation of new C-3-amino-substituted and C-5,6-alkyl-substituted analogues against clinically important HIV mutant strains.
    Benjahad A; Croisy M; Monneret C; Bisagni E; Mabire D; Coupa S; Poncelet A; Csoka I; Guillemont J; Meyer C; Andries K; Pauwels R; de Béthune MP; Himmel DM; Das K; Arnold E; Nguyen CH; Grierson DS
    J Med Chem; 2005 Mar; 48(6):1948-64. PubMed ID: 15771439
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationship studies on new DABOS: effect of substitutions at pyrimidine C-5 and C-6 positions on anti-HIV-1 activity.
    Sbardella G; Mai A; Artico M; Chimenti P; Massa S; Loddo R; Marongiu ME; La Collat P; Pani A
    Antivir Chem Chemother; 2001 Jan; 12(1):37-50. PubMed ID: 11437321
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes.
    Rotili D; Tarantino D; Nawrozkij MB; Babushkin AS; Botta G; Marrocco B; Cirilli R; Menta S; Badia R; Crespan E; Ballante F; Ragno R; Esté JA; Maga G; Mai A
    J Med Chem; 2014 Jun; 57(12):5212-25. PubMed ID: 24933420
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.