BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 14761199)

  • 1. Synthesis of mono- and bisdihydrodipyridopyrazines and assessment of their DNA binding and cytotoxic properties.
    Blanchard S; Rodriguez I; Tardy C; Baldeyrou B; Bailly C; Colson P; Houssier C; Léonce S; Kraus-Berthier L; Pfeiffer B; Renard P; Pierré A; Caubère P; Guillaumet G
    J Med Chem; 2004 Feb; 47(4):978-87. PubMed ID: 14761199
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4-Hydroxymethyl-3-aminoacridine derivatives as a new family of anticancer agents.
    Charmantray F; Demeunynck M; Carrez D; Croisy A; Lansiaux A; Bailly C; Colson P
    J Med Chem; 2003 Mar; 46(6):967-77. PubMed ID: 12620073
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives.
    Perni RB; Wentland MP; Huang JI; Powles RG; Aldous S; Klingbeil KM; Peverly AD; Robinson RG; Corbett TH; Jones JL; Mattes KC; Rake JB; Coughlin SA
    J Med Chem; 1998 Sep; 41(19):3645-54. PubMed ID: 9733489
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: various DNA binding geometry and interesting antitumor capacity.
    Zhang Z; Yang Y; Zhang D; Wang Y; Qian X; Liu F
    Bioorg Med Chem; 2006 Oct; 14(20):6962-70. PubMed ID: 16828559
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, antitumor evaluation and DNA photocleaving activity of novel methylthiazonaphthalimides with aminoalkyl side chains.
    Li Z; Yang Q; Qian X
    Bioorg Med Chem Lett; 2005 Jun; 15(12):3143-6. PubMed ID: 15876532
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel thiazonaphthalimides as efficient antitumor and DNA photocleaving agents: effects of intercalation, side chains, and substituent groups.
    Li Z; Yang Q; Qian X
    Bioorg Med Chem; 2005 Aug; 13(16):4864-70. PubMed ID: 15925513
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytotoxic and DNA binding properties of aminoalkyl derivatives of di- and triazaphenanthrenes.
    Argiropoulos G; Bates MR; Cherubim P; Deady LW; Ganakas AM; Baguley BC; Denny WA
    Anticancer Drug Des; 1992 Aug; 7(4):285-96. PubMed ID: 1510798
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antitumor agents. 3. Design, synthesis, and biological evaluation of new pyridoisoquinolindione and dihydrothienoquinolindione derivatives with potent cytotoxic activity.
    Bolognese A; Correale G; Manfra M; Lavecchia A; Mazzoni O; Novellino E; La Colla P; Sanna G; Loddo R
    J Med Chem; 2004 Feb; 47(4):849-58. PubMed ID: 14761187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and cytotoxic evaluation of a new series of 3-substituted spiro[(dihydropyrazine-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)] derivatives.
    Gomez-Monterrey I; Campiglia P; Carotenuto A; Califano D; Pisano C; Vesci L; Lama T; Bertamino A; Sala M; di Bosco AM; Grieco P; Novellino E
    J Med Chem; 2007 Apr; 50(8):1787-98. PubMed ID: 17375902
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel antitumor agent family of 1H-benzo[c,d]indol-2-one with flexible basic side chains: synthesis and biological evaluation.
    Yin H; Xu Y; Qian X
    Bioorg Med Chem; 2007 Feb; 15(3):1356-62. PubMed ID: 17129733
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents.
    Antonini I; Polucci P; Magnano A; Gatto B; Palumbo M; Menta E; Pescalli N; Martelli S
    J Med Chem; 2003 Jul; 46(14):3109-15. PubMed ID: 12825949
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chromophore-modified bisnaphthalimides: DNA recognition, topoisomerase inhibition, and cytotoxic properties of two mono- and bisfuronaphthalimides.
    Bailly C; Carrasco C; Joubert A; Bal C; Wattez N; Hildebrand MP; Lansiaux A; Colson P; Houssier C; Cacho M; Ramos A; Braña MF
    Biochemistry; 2003 Apr; 42(14):4136-50. PubMed ID: 12680768
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel antitumor indenoindole derivatives targeting DNA and topoisomerase II.
    Bal C; Baldeyrou B; Moz F; Lansiaux A; Colson P; Kraus-Berthier L; Léonce S; Pierré A; Boussard MF; Rousseau A; Wierzbicki M; Bailly C
    Biochem Pharmacol; 2004 Nov; 68(10):1911-22. PubMed ID: 15476662
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dimeric analogues of non-cationic tricyclic aromatic carboxamides are a new class of cytotoxic agents.
    Spicer JA; Gamage SA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    Anticancer Drug Des; 1999 Jun; 14(3):281-9. PubMed ID: 10500503
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Highly stable phenanthridinium frameworks as a new class of tunable DNA binding agents with cytotoxic properties.
    Parenty AD; Smith LV; Guthrie KM; Long DL; Plumb J; Brown R; Cronin L
    J Med Chem; 2005 Jul; 48(14):4504-6. PubMed ID: 15999988
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA binding to guide the development of tetrahydroindeno[1,2-b]pyrido[4,3,2-de]quinoline derivatives as cytotoxic agents.
    Catoen-Chackal S; Facompré M; Houssin R; Pommery N; Goossens JF; Colson P; Bailly C; Hénichart JP
    J Med Chem; 2004 Jul; 47(14):3665-73. PubMed ID: 15214793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 1-[(omega-aminoalkyl)amino]-4-[N-(omega-aminoalkyl)carbamoyl]-9-oxo-9, 10-dihydroacridines as intercalating cytotoxic agents: synthesis, DNA binding, and biological evaluation.
    Antonini I; Polucci P; Jenkins TC; Kelland LR; Menta E; Pescalli N; Stefanska B; Mazerski J; Martelli S
    J Med Chem; 1997 Nov; 40(23):3749-55. PubMed ID: 9371240
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of amino-substituted benzo[f]pyrido[4,3-b] and pyrido[3,4-b]quinoxalines: a new class of antineoplastic agents.
    Nguyen CH; Fan E; Riou JF; Bissery MC; Vrignaud P; Lavelle F; Bisagni E
    Anticancer Drug Des; 1995 Jun; 10(4):277-97. PubMed ID: 7786395
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amine-guanidine switch: a promising approach to improve DNA binding and antiproliferative activities.
    Ohara K; Smietana M; Restouin A; Mollard S; Borg JP; Collette Y; Vasseur JJ
    J Med Chem; 2007 Dec; 50(26):6465-75. PubMed ID: 18052116
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Peptidyl anthraquinones as potential antineoplastic drugs: synthesis, DNA binding, redox cycling, and biological activity.
    Gatto B; Zagotto G; Sissi C; Cera C; Uriarte E; Palù G; Capranico G; Palumbo M
    J Med Chem; 1996 Aug; 39(16):3114-22. PubMed ID: 8759632
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.