751 related articles for article (PubMed ID: 14761205)
1. Preparation, properties, reactions, and adenosine receptor affinities of sulfophenylxanthine nitrophenyl esters: toward the development of sulfonic acid prodrugs with peroral bioavailability.
Yan L; Müller CE
J Med Chem; 2004 Feb; 47(4):1031-43. PubMed ID: 14761205
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.
Baraldi PG; Tabrizi MA; Preti D; Bovero A; Romagnoli R; Fruttarolo F; Zaid NA; Moorman AR; Varani K; Gessi S; Merighi S; Borea PA
J Med Chem; 2004 Mar; 47(6):1434-47. PubMed ID: 14998332
[TBL] [Abstract][Full Text] [Related]
3. A new synthesis of sulfonamides by aminolysis of p-nitrophenylsulfonates yielding potent and selective adenosine A2B receptor antagonists.
Yan L; Bertarelli DC; Hayallah AM; Meyer H; Klotz KN; Müller CE
J Med Chem; 2006 Jul; 49(14):4384-91. PubMed ID: 16821798
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.
Balo MC; Brea J; Caamaño O; Fernández F; García-Mera X; López C; Loza MI; Nieto MI; Rodríguez-Borges JE
Bioorg Med Chem; 2009 Sep; 17(18):6755-60. PubMed ID: 19682912
[TBL] [Abstract][Full Text] [Related]
5. Development of spin-labeled probes for adenosine receptors.
Ilas J; Pecar S; Hockemeyer J; Euler H; Kirfel A; Müller CE
J Med Chem; 2005 Mar; 48(6):2108-14. PubMed ID: 15771453
[TBL] [Abstract][Full Text] [Related]
6. 1,3-dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships.
Fernández F; Caamaño O; Isabel Nieto M; López C; García-Mera X; Stefanachi A; Nicolotti O; Isabel Loza M; Brea J; Esteve C; Segarra V; Vidal B; Carotti A
Bioorg Med Chem; 2009 May; 17(10):3618-29. PubMed ID: 19398343
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists.
Rodríguez-Borges JE; García-Mera X; Balo MC; Brea J; Caamaño O; Fernández F; López C; Loza MI; Nieto MI
Bioorg Med Chem; 2010 Mar; 18(5):2001-9. PubMed ID: 20137957
[TBL] [Abstract][Full Text] [Related]
8. Potent and orally bioavailable 8-bicyclo[2.2.2]octylxanthines as adenosine A1 receptor antagonists.
Kiesman WF; Zhao J; Conlon PR; Dowling JE; Petter RC; Lutterodt F; Jin X; Smits G; Fure M; Jayaraj A; Kim J; Sullivan G; Linden J
J Med Chem; 2006 Nov; 49(24):7119-31. PubMed ID: 17125264
[TBL] [Abstract][Full Text] [Related]
9. Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists.
Kalla RV; Elzein E; Perry T; Li X; Palle V; Varkhedkar V; Gimbel A; Maa T; Zeng D; Zablocki J
J Med Chem; 2006 Jun; 49(12):3682-92. PubMed ID: 16759111
[TBL] [Abstract][Full Text] [Related]
10. 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity.
Borrmann T; Hinz S; Bertarelli DC; Li W; Florin NC; Scheiff AB; Müller CE
J Med Chem; 2009 Jul; 52(13):3994-4006. PubMed ID: 19569717
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor.
Carotti A; Cadavid MI; Centeno NB; Esteve C; Loza MI; Martinez A; Nieto R; Raviña E; Sanz F; Segarra V; Sotelo E; Stefanachi A; Vidal B
J Med Chem; 2006 Jan; 49(1):282-99. PubMed ID: 16392813
[TBL] [Abstract][Full Text] [Related]
12. 1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists.
Hayallah AM; Sandoval-Ramírez J; Reith U; Schobert U; Preiss B; Schumacher B; Daly JW; Müller CE
J Med Chem; 2002 Mar; 45(7):1500-10. PubMed ID: 11906291
[TBL] [Abstract][Full Text] [Related]
13. 1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor.
Stefanachi A; Brea JM; Cadavid MI; Centeno NB; Esteve C; Loza MI; Martinez A; Nieto R; Raviña E; Sanz F; Segarra V; Sotelo E; Vidal B; Carotti A
Bioorg Med Chem; 2008 Mar; 16(6):2852-69. PubMed ID: 18226909
[TBL] [Abstract][Full Text] [Related]
14. Novel 1,3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)-xanthine derivatives as high affinity and selective A2B adenosine receptor antagonists.
Elzein E; Kalla R; Li X; Perry T; Parkhill E; Palle V; Varkhedkar V; Gimbel A; Zeng D; Lustig D; Leung K; Zablocki J
Bioorg Med Chem Lett; 2006 Jan; 16(2):302-6. PubMed ID: 16275090
[TBL] [Abstract][Full Text] [Related]
15. 1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists.
Tabrizi MA; Baraldi PG; Preti D; Romagnoli R; Saponaro G; Baraldi S; Moorman AR; Zaid AN; Varani K; Borea PA
Bioorg Med Chem; 2008 Mar; 16(5):2419-30. PubMed ID: 18077171
[TBL] [Abstract][Full Text] [Related]
16. De novo analysis of receptor binding affinity data of 8-ethenyl-xanthine antagonists to adenosine A1 and A2a receptors.
Dalpiaz A; Gessi S; Varani K; Borea PA
Arzneimittelforschung; 1997 May; 47(5):591-4. PubMed ID: 9205770
[TBL] [Abstract][Full Text] [Related]
17. Water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, A(2A)-selective adenosine receptor antagonists.
Sauer R; Maurinsh J; Reith U; Fülle F; Klotz KN; Müller CE
J Med Chem; 2000 Feb; 43(3):440-8. PubMed ID: 10669571
[TBL] [Abstract][Full Text] [Related]
18. Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.
Pastorin G; Da Ros T; Spalluto G; Deflorian F; Moro S; Cacciari B; Baraldi PG; Gessi S; Varani K; Borea PA
J Med Chem; 2003 Sep; 46(20):4287-96. PubMed ID: 13678407
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and preliminary evaluation of new 1- and 3-[1-(2-hydroxy-3-phenoxypropyl)]xanthines from 2-amino-2-oxazolines as potential A1 and A2A adenosine receptor antagonists.
Massip S; Guillon J; Bertarelli D; Bosc JJ; Léger JM; Lacher S; Bontemps C; Dupont T; Müller CE; Jarry C
Bioorg Med Chem; 2006 Apr; 14(8):2697-719. PubMed ID: 16386423
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and structure-activity relationships of 3,7-dimethyl-1-propargylxanthine derivatives, A2A-selective adenosine receptor antagonists.
Müller CE; Geis U; Hipp J; Schobert U; Frobenius W; Pawłowski M; Suzuki F; Sandoval-Ramírez J
J Med Chem; 1997 Dec; 40(26):4396-405. PubMed ID: 9435909
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
