BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 14769947)

  • 1. A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens.
    Hsieh AC; Bo R; Manola J; Vazquez F; Bare O; Khvorova A; Scaringe S; Sellers WR
    Nucleic Acids Res; 2004; 32(3):893-901. PubMed ID: 14769947
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Inhibition of PDK1 gene expression in esophageal cancer EC9706 cells by RNA interference and its effect on their malignant biological behavior].
    Yu J; Chen KS; Li YN; Yang J; Zhao L
    Zhonghua Zhong Liu Za Zhi; 2011 Jun; 33(6):410-4. PubMed ID: 21875479
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway.
    Meng Q; Xia C; Fang J; Rojanasakul Y; Jiang BH
    Cell Signal; 2006 Dec; 18(12):2262-71. PubMed ID: 16839745
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeted RNA interference of PI3K pathway components sensitizes colon cancer cells to TNF-related apoptosis-inducing ligand (TRAIL).
    Rychahou PG; Murillo CA; Evers BM
    Surgery; 2005 Aug; 138(2):391-7. PubMed ID: 16153452
    [TBL] [Abstract][Full Text] [Related]  

  • 5. siRNA-mediated integrin-linked kinase suppression: nonspecific effects of siRNA/cationic liposome complexes trigger changes in the expression of phosphorylated-AKT and mTOR independently of ILK silencing.
    Verreault M; Bally MB
    Oligonucleotides; 2009 Jun; 19(2):129-40. PubMed ID: 19284309
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide-dependent kinase 1 (PDK1): an alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1.
    Kim DW; Hwang JH; Suh JM; Kim H; Song JH; Hwang ES; Hwang IY; Park KC; Chung HK; Kim JM; Park J; Hemmings BA; Shong M
    Mol Endocrinol; 2003 Jul; 17(7):1382-94. PubMed ID: 12738763
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions.
    Schubert S; Grünweller A; Erdmann VA; Kurreck J
    J Mol Biol; 2005 May; 348(4):883-93. PubMed ID: 15843020
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting of integrin-linked kinase with small interfering RNA inhibits VEGF-induced angiogenesis in retinal endothelial cells.
    Xie W; Zhao M; Zhou W; Guo L; Huang L; Yu W; Li X
    Ophthalmic Res; 2013; 49(3):139-49. PubMed ID: 23258222
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development.
    Burchert A; Wang Y; Cai D; von Bubnoff N; Paschka P; Müller-Brüsselbach S; Ottmann OG; Duyster J; Hochhaus A; Neubauer A
    Leukemia; 2005 Oct; 19(10):1774-82. PubMed ID: 16136169
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhancement of DC vaccine potency by activating the PI3K/AKT pathway with a small interfering RNA targeting PTEN.
    Kim JH; Kang TH; Noh KH; Kim SH; Lee YH; Kim KW; Bae HC; Ahn YH; Choi EY; Kim JS; Lee KM; Kim TW
    Immunol Lett; 2010 Nov; 134(1):47-54. PubMed ID: 20727912
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeted RNA interference of phosphatidylinositol 3-kinase p110-beta induces apoptosis and proliferation arrest in endometrial carcinoma cells.
    An HJ; Cho NH; Yang HS; Kwak KB; Kim NK; Oh DY; Lee SW; Kim HO; Koh JJ
    J Pathol; 2007 Jun; 212(2):161-9. PubMed ID: 17427168
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.
    Harborth J; Elbashir SM; Vandenburgh K; Manninga H; Scaringe SA; Weber K; Tuschl T
    Antisense Nucleic Acid Drug Dev; 2003 Apr; 13(2):83-105. PubMed ID: 12804036
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gene silencing with siRNA duplexes composed of target-mRNA-complementary and partially palindromic or partially complementary single-stranded siRNAs.
    Hossbach M; Gruber J; Osborn M; Weber K; Tuschl T
    RNA Biol; 2006 Apr; 3(2):82-9. PubMed ID: 17114944
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HIF-1alpha has an anti-apoptotic effect in human airway epithelium that is mediated via Mcl-1 gene expression.
    Liu XH; Yu EZ; Li YY; Kagan E
    J Cell Biochem; 2006 Mar; 97(4):755-65. PubMed ID: 16229017
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA.
    Czauderna F; Fechtner M; Aygün H; Arnold W; Klippel A; Giese K; Kaufmann J
    Nucleic Acids Res; 2003 Jan; 31(2):670-82. PubMed ID: 12527776
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts.
    Fuka G; Kantner HP; Grausenburger R; Inthal A; Bauer E; Krapf G; Kaindl U; Kauer M; Dworzak MN; Stoiber D; Haas OA; Panzer-Grümayer R
    Leukemia; 2012 May; 26(5):927-33. PubMed ID: 22094587
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Asymmetric RNA duplexes mediate RNA interference in mammalian cells.
    Sun X; Rogoff HA; Li CJ
    Nat Biotechnol; 2008 Dec; 26(12):1379-82. PubMed ID: 19029911
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Downregulation of c-Met expression does not enhance the sensitivity of gastric cancer cell line MKN-45 to gefitinib.
    Ma JA; Hu C; Li W; Ren J; Zou F; Zhou D; Zou W; Wei Y; Zhou Y
    Mol Med Rep; 2015 Mar; 11(3):2269-75. PubMed ID: 25395073
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of Akt kinase-interacting protein 1, a scaffold protein of the PI3K/PDK1/Akt pathway, in pancreatic cancer.
    Ohtsubo K; Yamada T; Zhao L; Jin TF; Takeuchi S; Mouri H; Yamashita K; Yasumoto K; Fujita N; Kitagawa H; Ohta T; Ikeda H; Yano S
    Pancreas; 2014 Oct; 43(7):1093-100. PubMed ID: 25036909
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A bi-functional siRNA construct induces RNA interference and also primes PCR amplification for its own quantification.
    Jiang M; Arzumanov AA; Gait MJ; Milner J
    Nucleic Acids Res; 2005 Oct; 33(18):e151. PubMed ID: 16214804
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.