These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 1479583)

  • 1. Hypoxia-selective antitumor agents. 6. 4-(Alkylamino)nitroquinolines: a new class of hypoxia-selective cytotoxins.
    Denny WA; Atwell GJ; Roberts PB; Anderson RF; Boyd M; Lock CJ; Wilson WR
    J Med Chem; 1992 Dec; 35(26):4832-41. PubMed ID: 1479583
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypoxia-selective antitumor agents. 15. Modification of rate of nitroreduction and extent of lysosomal uptake by polysubstitution of 4-(alkylamino)-5-nitroquinoline bioreductive drugs.
    Siim BG; Atwell GJ; Anderson RF; Wardman P; Pullen SM; Wilson WR; Denny WA
    J Med Chem; 1997 Apr; 40(9):1381-90. PubMed ID: 9135035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxia-selective antitumor agents. 14. Synthesis and hypoxic cell cytotoxicity of regioisomers of the hypoxia-selective cytotoxin 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
    Palmer BD; Wilson WR; Anderson RF; Boyd M; Denny WA
    J Med Chem; 1996 Jun; 39(13):2518-28. PubMed ID: 8691449
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Radiosensitizing and toxic properties of quinoline and nitroquinoline complexes of platinum [PtCl2(NH3)quinoline].
    Skov KA; Adomat H; Doedee M; Farrell N
    Anticancer Drug Des; 1994 Apr; 9(2):103-17. PubMed ID: 8166927
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia-selective antitumor agents. 8. Bis(nitroimidazolyl)alkanecarboxamides: a new class of hypoxia-selective cytotoxins and hypoxic cell radiosensitisers.
    Hay MP; Wilson WR; Moselen JW; Palmer BD; Denny WA
    J Med Chem; 1994 Feb; 37(3):381-91. PubMed ID: 8308864
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-activity relationships of 1,2,4-benzotriazine 1,4-dioxides as hypoxia-selective analogues of tirapazamine.
    Hay MP; Gamage SA; Kovacs MS; Pruijn FB; Anderson RF; Patterson AV; Wilson WR; Brown JM; Denny WA
    J Med Chem; 2003 Jan; 46(1):169-82. PubMed ID: 12502371
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolic and radiolytic reduction of 4-alkylamino-5-nitroquinoline bioreductive drugs. Relationship to hypoxia-selective cytotoxicity.
    Siim BG; Atwell GJ; Wilson WR
    Biochem Pharmacol; 1994 Oct; 48(8):1593-604. PubMed ID: 7980625
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypoxia-selective antitumor agents. 13. Effects of acridine substitution on the hypoxia-selective cytotoxicity and metabolic reduction of the bis-bioreductive agent nitracrine N-oxide.
    Lee HH; Wilson WR; Ferry DM; van Zijl P; Pullen SM; Denny WA
    J Med Chem; 1996 Jun; 39(13):2508-17. PubMed ID: 8691448
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nitracrine N-oxides: effects of variations in the nature of the side chain N-oxide on hypoxia-selective cytotoxicity.
    Lee HH; Wilson WR; Denny WA
    Anticancer Drug Des; 1999 Dec; 14(6):487-97. PubMed ID: 10834270
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia-selective antitumor agents. 7. Metal complexes of aliphatic mustards as a new class of hypoxia-selective cytotoxins. Synthesis and evaluation of cobalt(III) complexes of bidentate mustards.
    Ware DC; Palmer BD; Wilson WR; Denny WA
    J Med Chem; 1993 Jun; 36(13):1839-46. PubMed ID: 8515422
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypoxia-selective antitumor agents. 12. Nitrobenzyl quaternary salts as bioreductive prodrugs of the alkylating agent mechlorethamine.
    Tercel M; Wilson WR; Anderson RF; Denny WA
    J Med Chem; 1996 Mar; 39(5):1084-94. PubMed ID: 8676343
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hypoxia-selective antitumor agents. 5. Synthesis of water-soluble nitroaniline mustards with selective cytotoxicity for hypoxic mammalian cells.
    Palmer BD; Wilson WR; Cliffe S; Denny WA
    J Med Chem; 1992 Aug; 35(17):3214-22. PubMed ID: 1507207
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovering novel 3-nitroquinolines as a new class of anticancer agents.
    Li HH; Huang H; Zhang XH; Luo XM; Lin LP; Jiang HL; Ding J; Chen KX; Liu H
    Acta Pharmacol Sin; 2008 Dec; 29(12):1529-38. PubMed ID: 19026174
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypoxia-selective antitumor agents. 4. Relationships between structure, physicochemical properties, and hypoxia-selective cytotoxicity for nitracrine analogues with varying side chains: the "iminoacridan hypothesis".
    Denny WA; Atwell GJ; Anderson RF; Wilson WR
    J Med Chem; 1990 May; 33(5):1288-95. PubMed ID: 2329552
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, microwave-mediated synthesis and biological evaluation of novel 4-aryl(alkyl)amino-3-nitroquinoline and 2,4-diaryl(dialkyl)amino-3-nitroquinolines as anticancer agents.
    Chauhan M; Rana A; Alex JM; Negi A; Singh S; Kumar R
    Bioorg Chem; 2015 Feb; 58():1-10. PubMed ID: 25462621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 5-Nitro-4-(N,N-dimethylaminopropylamino)quinoline (5-nitraquine), a new DNA-affinic hypoxic cell radiosensitizer and bioreductive agent: comparison with nitracrine.
    Wilson WR; Siim BG; Denny WA; van Zijl PL; Taylor ML; Chambers DM; Roberts PB
    Radiat Res; 1992 Sep; 131(3):257-65. PubMed ID: 1438685
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypoxia-selective antitumor agents. 10. bis(nitroimidazoles) and related Bis(nitroheterocycles): development of derivatives with higher rates of metabolic activation under hypoxia and improved aqueous solubility.
    Hay MP; Lee HH; Wilson WR; Roberts PB; Denny WA
    J Med Chem; 1995 May; 38(11):1928-41. PubMed ID: 7783125
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heterocyclic mono-N-oxides with potential applications as bioreductive anti-tumour drugs: Part 1. 8-Alkylamino-substituted phenylimidazo [1,2-a] quinoxalines.
    Naylor MA; Stephens MA; Nolan J; Sutton B; Tocher JH; Fielden EM; Adams GE; Stratford IJ
    Anticancer Drug Des; 1993 Dec; 8(6):439-61. PubMed ID: 8286012
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nitro analogues of chlorambucil as potential hypoxia-selective anti-tumour drugs.
    Palmer BD; Wilson WR; Denny WA
    Anticancer Drug Des; 1990 Nov; 5(4):337-49. PubMed ID: 2291774
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hypoxia-selective antitumor agents. 3. Relationships between structure and cytotoxicity against cultured tumor cells for substituted N,N-bis(2-chloroethyl)anilines.
    Palmer BD; Wilson WR; Pullen SM; Denny WA
    J Med Chem; 1990 Jan; 33(1):112-21. PubMed ID: 2296009
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.