119 related articles for article (PubMed ID: 1480613)
1. Site-directed mutagenesis and X-ray crystallography of two phospholipase A2 mutants: Y52F and Y73F.
Thunnissen MM; Franken PA; de Haas GH; Drenth J; Kalk KH; Verheij HM; Dijkstra BW
Protein Eng; 1992 Oct; 5(7):597-603. PubMed ID: 1480613
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure of the Y52F/Y73F double mutant of phospholipase A2: increased hydrophobic interactions of the phenyl groups compensate for the disrupted hydrogen bonds of the tyrosines.
Sekharudu C; Ramakrishnan B; Huang B; Jiang RT; Dupureur CM; Tsai MD; Sundaralingam M
Protein Sci; 1992 Dec; 1(12):1585-94. PubMed ID: 1304890
[TBL] [Abstract][Full Text] [Related]
3. Function of the fully conserved residues Asp99, Tyr52 and Tyr73 in phospholipase A2.
Kuipers OP; Franken PA; Hendriks R; Verheij HM; de Haas GH
Protein Eng; 1990 Dec; 4(2):199-204. PubMed ID: 2075195
[TBL] [Abstract][Full Text] [Related]
4. Catalytic role of the active site histidine of porcine pancreatic phospholipase A2 probed by the variants H48Q, H48N and H48K.
Janssen MJ; van de Wiel WA; Beiboer SH; van Kampen MD; Verheij HM; Slotboom AJ; Egmond MR
Protein Eng; 1999 Jun; 12(6):497-503. PubMed ID: 10388847
[TBL] [Abstract][Full Text] [Related]
5. Phospholipase A2 engineering. The roles of disulfide bonds in structure, conformational stability, and catalytic function.
Zhu H; Dupureur CM; Zhang X; Tsai MD
Biochemistry; 1995 Nov; 34(46):15307-14. PubMed ID: 7578147
[TBL] [Abstract][Full Text] [Related]
6. Modification of the stability of phospholipase A2 by charge engineering.
Pickersgill RW; Sumner IG; Collins ME; Warwicker J; Perry B; Bhat KM; Goodenough PW
FEBS Lett; 1991 Apr; 281(1-2):219-22. PubMed ID: 2015898
[TBL] [Abstract][Full Text] [Related]
7. Phospholipase A2 engineering. Probing the structural and functional roles of N-terminal residues with site-directed mutagenesis, X-ray, and NMR.
Liu X; Zhu H; Huang B; Rogers J; Yu BZ; Kumar A; Jain MK; Sundaralingam M; Tsai MD
Biochemistry; 1995 Jun; 34(22):7322-34. PubMed ID: 7779775
[TBL] [Abstract][Full Text] [Related]
8. The crystal structure of a lysine 49 phospholipase A2 from the venom of the cottonmouth snake at 2.0-A resolution.
Holland DR; Clancy LL; Muchmore SW; Ryde TJ; Einspahr HM; Finzel BC; Heinrikson RL; Watenpaugh KD
J Biol Chem; 1990 Oct; 265(29):17649-56. PubMed ID: 2120215
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure of a porcine pancreatic phospholipase A2 mutant. A large conformational change caused by the F63V point mutation.
Thunnissen MM; Franken PA; de Haas GH; Drenth J; Kalk KH; Verheij HM; Dijkstra BW
J Mol Biol; 1993 Aug; 232(3):839-55. PubMed ID: 8355274
[TBL] [Abstract][Full Text] [Related]
10. Atomic resolution (0.97 A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2.
Sekar K; Rajakannan V; Gayathri D; Velmurugan D; Poi MJ; Dauter M; Dauter Z; Tsai MD
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2005 Jan; 61(Pt 1):3-7. PubMed ID: 16508077
[TBL] [Abstract][Full Text] [Related]
11. Phospholipase A2 engineering. Structural and functional roles of highly conserved active site residues tyrosine-52 and tyrosine-73.
Dupureur CM; Yu BZ; Jain MK; Noel JP; Deng T; Li Y; Byeon IJ; Tsai MD
Biochemistry; 1992 Jul; 31(28):6402-13. PubMed ID: 1633153
[TBL] [Abstract][Full Text] [Related]
12. Phospholipase A2 engineering. Deletion of the C-terminus segment changes substrate specificity and uncouples calcium and substrate binding at the zwitterionic interface.
Huang B; Yu BZ; Rogers J; Byeon IJ; Sekar K; Chen X; Sundaralingam M; Tsai MD; Jain MK
Biochemistry; 1996 Sep; 35(37):12164-74. PubMed ID: 8810924
[TBL] [Abstract][Full Text] [Related]
13. Structure of an engineered porcine phospholipase A2 with enhanced activity at 2.1 A resolution. Comparison with the wild-type porcine and Crotalus atrox phospholipase A2.
Thunnissen MM; Kalk KH; Drenth J; Dijkstra BW
J Mol Biol; 1990 Nov; 216(2):425-39. PubMed ID: 2254938
[TBL] [Abstract][Full Text] [Related]
14. 1.72 A resolution refinement of the trigonal form of bovine pancreatic phospholipase A2.
Sekar K; Sekharudu C; Tsai MD; Sundaralingam M
Acta Crystallogr D Biol Crystallogr; 1998 May; 54(Pt 3):342-6. PubMed ID: 9761901
[TBL] [Abstract][Full Text] [Related]
15. Phospholipase A2 engineering. X-ray structural and functional evidence for the interaction of lysine-56 with substrates.
Noel JP; Bingman CA; Deng TL; Dupureur CM; Hamilton KJ; Jiang RT; Kwak JG; Sekharudu C; Sundaralingam M; Tsai MD
Biochemistry; 1991 Dec; 30(51):11801-11. PubMed ID: 1751497
[TBL] [Abstract][Full Text] [Related]
16. Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-99.
Sekar K; Yu BZ; Rogers J; Lutton J; Liu X; Chen X; Tsai MD; Jain MK; Sundaralingam M
Biochemistry; 1997 Mar; 36(11):3104-14. PubMed ID: 9115986
[TBL] [Abstract][Full Text] [Related]
17. High-resolution refinement of orthorhombic bovine pancreatic phospholipase A2.
Sekar K; Sundaralingam M
Acta Crystallogr D Biol Crystallogr; 1999 Jan; 55(Pt 1):46-50. PubMed ID: 10089393
[TBL] [Abstract][Full Text] [Related]
18. First structural evidence of a specific inhibition of phospholipase A2 by alpha-tocopherol (vitamin E) and its implications in inflammation: crystal structure of the complex formed between phospholipase A2 and alpha-tocopherol at 1.8 A resolution.
Chandra V; Jasti J; Kaur P; Betzel Ch; Srinivasan A; Singh TP
J Mol Biol; 2002 Jul; 320(2):215-22. PubMed ID: 12079380
[TBL] [Abstract][Full Text] [Related]
19. Role of amino acid residues at turns in the conformational stability and folding of human lysozyme.
Takano K; Yamagata Y; Yutani K
Biochemistry; 2000 Jul; 39(29):8655-65. PubMed ID: 10913274
[TBL] [Abstract][Full Text] [Related]
20. Observation of additional calcium ion in the crystal structure of the triple mutant K56,120,121M of bovine pancreatic phospholipase A2.
Rajakannan V; Yogavel M; Poi MJ; Jeyaprakash AA; Jeyakanthan J; Velmurugan D; Tsai MD; Sekar K
J Mol Biol; 2002 Dec; 324(4):755-62. PubMed ID: 12460575
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]