These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

68 related articles for article (PubMed ID: 14871582)

  • 1. Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation).
    Dorne JL; Walton K; Renwick AG
    Food Chem Toxicol; 2004 Mar; 42(3):397-421. PubMed ID: 14871582
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review.
    Dorne JL; Walton K; Renwick AG
    Food Chem Toxicol; 2005 Feb; 43(2):203-16. PubMed ID: 15621332
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Impact of inter-individual differences in drug metabolism and pharmacokinetics on safety evaluation.
    Dorne JL
    Fundam Clin Pharmacol; 2004 Dec; 18(6):609-20. PubMed ID: 15548231
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for risk assessment.
    Dorne JL; Walton K; Renwick AG
    Food Chem Toxicol; 2003 Feb; 41(2):201-24. PubMed ID: 12480298
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Polymorphic CYP2C19 and N-acetylation: human variability in kinetics and pathway-related uncertainty factors.
    Dorne JL; Walton K; Renwick AG
    Food Chem Toxicol; 2003 Feb; 41(2):225-45. PubMed ID: 12480299
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human variability in hepatic and renal elimination: implications for risk assessment.
    Dorne JL
    J Appl Toxicol; 2007; 27(5):411-20. PubMed ID: 17497760
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?
    Dorne JL; Walton K; Slob W; Renwick AG
    Food Chem Toxicol; 2002 Nov; 40(11):1633-56. PubMed ID: 12176090
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene.
    Nong A; McCarver DG; Hines RN; Krishnan K
    Toxicol Appl Pharmacol; 2006 Jul; 214(1):78-87. PubMed ID: 16464483
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms.
    García-Martín E; Martínez C; Tabarés B; Frías J; Agúndez JA
    Clin Pharmacol Ther; 2004 Aug; 76(2):119-27. PubMed ID: 15289789
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human variability in the renal elimination of foreign compounds and renal excretion-related uncertainty factors for risk assessment.
    Dorne JL; Walton K; Renwick AG
    Food Chem Toxicol; 2004 Feb; 42(2):275-98. PubMed ID: 14667473
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human variability in glucuronidation in relation to uncertainty factors for risk assessment.
    Dorne JL; Walton K; Renwick AG
    Food Chem Toxicol; 2001 Dec; 39(12):1153-73. PubMed ID: 11696390
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alcohol dehydrogenase and catalase content in perinatal infant and adult livers: potential influence on neonatal alcohol metabolism.
    Tran MN; Wu AH; Hill DW
    Toxicol Lett; 2007 Mar; 169(3):245-52. PubMed ID: 17343998
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Individual susceptibility and alcohol effects:biochemical and genetic aspects.
    Gemma S; Vichi S; Testai E
    Ann Ist Super Sanita; 2006; 42(1):8-16. PubMed ID: 16801720
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes.
    Parkinson A; Mudra DR; Johnson C; Dwyer A; Carroll KM
    Toxicol Appl Pharmacol; 2004 Sep; 199(3):193-209. PubMed ID: 15364537
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of diuron N-demethylation by mammalian hepatic microsomes and cDNA-expressed human cytochrome P450 enzymes.
    Abass K; Reponen P; Turpeinen M; Jalonen J; Pelkonen O
    Drug Metab Dispos; 2007 Sep; 35(9):1634-41. PubMed ID: 17576805
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genetic polymorphisms in assessing interindividual variability in delivered dose.
    Haber LT; Maier A; Gentry PR; Clewell HJ; Dourson ML
    Regul Toxicol Pharmacol; 2002 Apr; 35(2 Pt 1):177-97. PubMed ID: 12052003
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differences in pharmacogenetics of nicotine and alcohol metabolism: review and recommendations for future research.
    Wall TL; Schoedel K; Ring HZ; Luczak SE; Katsuyoshi DM; Tyndale RF
    Nicotine Tob Res; 2007 Sep; 9 Suppl 3():S459-74. PubMed ID: 17978975
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A phase I, randomized, open-label, crossover study of the single-dose pharmacokinetic properties of guanfacine extended-release 1-, 2-, and 4-mg tablets in healthy adults.
    Swearingen D; Pennick M; Shojaei A; Lyne A; Fiske K
    Clin Ther; 2007 Apr; 29(4):617-25. PubMed ID: 17617285
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Uncertainty factors for chemical risk assessment. human variability in the pharmacokinetics of CYP1A2 probe substrates.
    Dorne JL; Walton K; Renwick AG
    Food Chem Toxicol; 2001 Jul; 39(7):681-96. PubMed ID: 11397515
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
    EFSA GMO Panel Working Group on Animal Feeding Trials
    Food Chem Toxicol; 2008 Mar; 46 Suppl 1():S2-70. PubMed ID: 18328408
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.