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2. Specialization of the DNA-cleaving activity of a group I ribozyme through in vitro evolution. Tsang J; Joyce GF J Mol Biol; 1996 Sep; 262(1):31-42. PubMed ID: 8809177 [TBL] [Abstract][Full Text] [Related]
3. Evolutionary optimization of the catalytic properties of a DNA-cleaving ribozyme. Tsang J; Joyce GF Biochemistry; 1994 May; 33(19):5966-73. PubMed ID: 8180226 [TBL] [Abstract][Full Text] [Related]
4. Evolution in vitro: analysis of a lineage of ribozymes. Lehman N; Joyce GF Curr Biol; 1993; 3(11):723-34. PubMed ID: 11539560 [TBL] [Abstract][Full Text] [Related]
5. Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis. Legault P; Herschlag D; Celander DW; Cech TR Nucleic Acids Res; 1992 Dec; 20(24):6613-9. PubMed ID: 1480482 [TBL] [Abstract][Full Text] [Related]
6. RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme. Pyle AM; Murphy FL; Cech TR Nature; 1992 Jul; 358(6382):123-8. PubMed ID: 1377367 [TBL] [Abstract][Full Text] [Related]
7. Acquisition of novel catalytic activity by the M1 RNA ribozyme: the cost of molecular adaptation. Cole KB; Dorit RL J Mol Biol; 1999 Oct; 292(4):931-44. PubMed ID: 10525416 [TBL] [Abstract][Full Text] [Related]
8. Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA. Herschlag D; Eckstein F; Cech TR Biochemistry; 1993 Aug; 32(32):8299-311. PubMed ID: 7688572 [TBL] [Abstract][Full Text] [Related]
9. Experimental evolution of complexity: in vitro emergence of intermolecular ribozyme interactions. Hanczyc MM; Dorit RL RNA; 1998 Mar; 4(3):268-75. PubMed ID: 9510329 [TBL] [Abstract][Full Text] [Related]
10. Cleavage of an amide bond by a ribozyme. Dai X; De Mesmaeker A; Joyce GF Science; 1995 Jan; 267(5195):237-40. PubMed ID: 7809628 [TBL] [Abstract][Full Text] [Related]
11. Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu). Zaug AJ; Dávila-Aponte JA; Cech TR Biochemistry; 1994 Dec; 33(49):14935-47. PubMed ID: 7527660 [TBL] [Abstract][Full Text] [Related]
12. The P5abc peripheral element facilitates preorganization of the tetrahymena group I ribozyme for catalysis. Engelhardt MA; Doherty EA; Knitt DS; Doudna JA; Herschlag D Biochemistry; 2000 Mar; 39(10):2639-51. PubMed ID: 10704214 [TBL] [Abstract][Full Text] [Related]
13. Continuous in vitro evolution of a ribozyme that catalyzes three successive nucleotidyl addition reactions. McGinness KE; Wright MC; Joyce GF Chem Biol; 2002 May; 9(5):585-96. PubMed ID: 12031665 [TBL] [Abstract][Full Text] [Related]
14. Mutations in the Tetrahymena ribozyme internal guide sequence: effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity. Campbell TB; Cech TR Biochemistry; 1996 Sep; 35(35):11493-502. PubMed ID: 8784205 [TBL] [Abstract][Full Text] [Related]
15. Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA. Robertson DL; Joyce GF Nature; 1990 Mar; 344(6265):467-8. PubMed ID: 1690861 [TBL] [Abstract][Full Text] [Related]
16. The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction. Herschlag D; Eckstein F; Cech TR Biochemistry; 1993 Aug; 32(32):8312-21. PubMed ID: 7688573 [TBL] [Abstract][Full Text] [Related]
19. Tertiary interactions with the internal guide sequence mediate docking of the P1 helix into the catalytic core of the Tetrahymena ribozyme. Strobel SA; Cech TR Biochemistry; 1993 Dec; 32(49):13593-604. PubMed ID: 7504953 [TBL] [Abstract][Full Text] [Related]
20. Replicability and recurrence in the experimental evolution of a group I ribozyme. Hanczyc MM; Dorit RL Mol Biol Evol; 2000 Jul; 17(7):1050-60. PubMed ID: 10889218 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]