These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
139 related articles for article (PubMed ID: 14966129)
1. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates. Cheong CG; Wolan DW; Greasley SE; Horton PA; Beardsley GP; Wilson IA J Biol Chem; 2004 Apr; 279(17):18034-45. PubMed ID: 14966129 [TBL] [Abstract][Full Text] [Related]
2. Structural insights into the avian AICAR transformylase mechanism. Wolan DW; Greasley SE; Beardsley GP; Wilson IA Biochemistry; 2002 Dec; 41(52):15505-13. PubMed ID: 12501179 [TBL] [Abstract][Full Text] [Related]
3. Human AICAR transformylase: role of the 4-carboxamide of AICAR in binding and catalysis. Wall M; Shim JH; Benkovic SJ Biochemistry; 2000 Sep; 39(37):11303-11. PubMed ID: 10985775 [TBL] [Abstract][Full Text] [Related]
4. Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor. Wolan DW; Cheong CG; Greasley SE; Wilson IA Biochemistry; 2004 Feb; 43(5):1171-83. PubMed ID: 14756553 [TBL] [Abstract][Full Text] [Related]
5. Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site. Wolan DW; Greasley SE; Wall MJ; Benkovic SJ; Wilson IA Biochemistry; 2003 Sep; 42(37):10904-14. PubMed ID: 12974624 [TBL] [Abstract][Full Text] [Related]
6. Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) from Staphylococcus lugdunensis. Verma P; Kar B; Varshney R; Roy P; Sharma AK FEBS J; 2017 Dec; 284(24):4233-4261. PubMed ID: 29063699 [TBL] [Abstract][Full Text] [Related]
7. Human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase. A bifunctional protein requiring dimerization for transformylase activity but not for cyclohydrolase activity. Vergis JM; Bulock KG; Fleming KG; Beardsley GP J Biol Chem; 2001 Mar; 276(11):7727-33. PubMed ID: 11096114 [TBL] [Abstract][Full Text] [Related]
8. The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate channeling. Bulock KG; Beardsley GP; Anderson KS J Biol Chem; 2002 Jun; 277(25):22168-74. PubMed ID: 11948179 [TBL] [Abstract][Full Text] [Related]
9. Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) bifunctional enzyme from Candidatus Liberibacer asiaticus. Lonare S; Rode S; Verma P; Verma S; Kaur H; Alam MS; Wangmo P; Kumar P; Roy P; Sharma AK Biochim Biophys Acta Proteins Proteom; 2024 Jul; 1872(4):141015. PubMed ID: 38615986 [TBL] [Abstract][Full Text] [Related]
10. Structural analyses of a purine biosynthetic enzyme from Mycobacterium tuberculosis reveal a novel bound nucleotide. Le Nours J; Bulloch EM; Zhang Z; Greenwood DR; Middleditch MJ; Dickson JM; Baker EN J Biol Chem; 2011 Nov; 286(47):40706-16. PubMed ID: 21956117 [TBL] [Abstract][Full Text] [Related]
11. Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 A resolution. Axelrod HL; McMullan D; Krishna SS; Miller MD; Elsliger MA; Abdubek P; Ambing E; Astakhova T; Carlton D; Chiu HJ; Clayton T; Duan L; Feuerhelm J; Grzechnik SK; Hale J; Han GW; Haugen J; Jaroszewski L; Jin KK; Klock HE; Knuth MW; Koesema E; Morse AT; Nigoghossian E; Okach L; Oommachen S; Paulsen J; Quijano K; Reyes R; Rife CL; van den Bedem H; Weekes D; White A; Wolf G; Xu Q; Hodgson KO; Wooley J; Deacon AM; Godzik A; Lesley SA; Wilson IA Proteins; 2008 May; 71(2):1042-9. PubMed ID: 18260100 [No Abstract] [Full Text] [Related]
12. Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis. Greasley SE; Horton P; Ramcharan J; Beardsley GP; Benkovic SJ; Wilson IA Nat Struct Biol; 2001 May; 8(5):402-6. PubMed ID: 11323713 [TBL] [Abstract][Full Text] [Related]
13. Relationship between the catalytic sites of human bifunctional IMP synthase. Szabados E; Christopherson RI Int J Biochem Cell Biol; 1998 Aug; 30(8):933-42. PubMed ID: 9744084 [TBL] [Abstract][Full Text] [Related]
14. Catalytic mechanism of the cyclohydrolase activity of human aminoimidazole carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase. Vergis JM; Beardsley GP Biochemistry; 2004 Feb; 43(5):1184-92. PubMed ID: 14756554 [TBL] [Abstract][Full Text] [Related]
15. A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase. Kang YN; Tran A; White RH; Ealick SE Biochemistry; 2007 May; 46(17):5050-62. PubMed ID: 17407260 [TBL] [Abstract][Full Text] [Related]
16. Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors. Li C; Xu L; Wolan DW; Wilson IA; Olson AJ J Med Chem; 2004 Dec; 47(27):6681-90. PubMed ID: 15615517 [TBL] [Abstract][Full Text] [Related]
17. Radioassay of bifunctional 5-aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase by thin-layer chromatography. Szabados E; Christopherson RI Anal Biochem; 1994 Sep; 221(2):401-4. PubMed ID: 7810885 [TBL] [Abstract][Full Text] [Related]
18. Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening. Xu L; Li C; Olson AJ; Wilson IA J Biol Chem; 2004 Nov; 279(48):50555-65. PubMed ID: 15355974 [TBL] [Abstract][Full Text] [Related]
19. De novo purine nucleotide biosynthesis: cloning, sequencing and expression of a chicken PurH cDNA encoding 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase-IMP cyclohydrolase. Ni L; Guan K; Zalkin H; Dixon JE Gene; 1991 Oct; 106(2):197-205. PubMed ID: 1937050 [TBL] [Abstract][Full Text] [Related]
20. 5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase from human CCRF-CEM leukemia cells: purification, pH dependence, and inhibitors. Szabados E; Hindmarsh EJ; Phillips L; Duggleby RG; Christopherson RI Biochemistry; 1994 Nov; 33(47):14237-45. PubMed ID: 7947835 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]