156 related articles for article (PubMed ID: 14966133)
1. Cofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientation.
Shi R; Lin SX
J Biol Chem; 2004 Apr; 279(16):16778-85. PubMed ID: 14966133
[TBL] [Abstract][Full Text] [Related]
2. Crystal structures of human 17β-hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP
Li T; Stephen P; Zhu DW; Shi R; Lin SX
FEBS J; 2019 Jun; 286(11):2155-2166. PubMed ID: 30768851
[TBL] [Abstract][Full Text] [Related]
3. Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase.
Mazza C; Breton R; Housset D; Fontecilla-Camps JC
J Biol Chem; 1998 Apr; 273(14):8145-52. PubMed ID: 9525918
[TBL] [Abstract][Full Text] [Related]
4. The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors.
Breton R; Housset D; Mazza C; Fontecilla-Camps JC
Structure; 1996 Aug; 4(8):905-15. PubMed ID: 8805577
[TBL] [Abstract][Full Text] [Related]
5. Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase.
Qiu W; Zhou M; Mazumdar M; Azzi A; Ghanmi D; Luu-The V; Labrie F; Lin SX
J Biol Chem; 2007 Mar; 282(11):8368-79. PubMed ID: 17166832
[TBL] [Abstract][Full Text] [Related]
6. Structure and function of 3 alpha-hydroxysteroid dehydrogenase.
Penning TM; Bennett MJ; Smith-Hoog S; Schlegel BP; Jez JM; Lewis M
Steroids; 1997 Jan; 62(1):101-11. PubMed ID: 9029723
[TBL] [Abstract][Full Text] [Related]
7. Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+.
Sawicki MW; Erman M; Puranen T; Vihko P; Ghosh D
Proc Natl Acad Sci U S A; 1999 Feb; 96(3):840-5. PubMed ID: 9927655
[TBL] [Abstract][Full Text] [Related]
8. Structural basis of the multispecificity demonstrated by 17beta-hydroxysteroid dehydrogenase types 1 and 5.
Lin SX; Shi R; Qiu W; Azzi A; Zhu DW; Dabbagh HA; Zhou M
Mol Cell Endocrinol; 2006 Mar; 248(1-2):38-46. PubMed ID: 16480815
[TBL] [Abstract][Full Text] [Related]
9. Two non-reactive ternary complexes of estrogenic 17beta-hydroxysteroid dehydrogenase: crystallization and preliminary structural analysis.
Qiu W; Zhu DW; Azzi A; Campbell RL; Qi H; Poirier D; Lin SX
J Steroid Biochem Mol Biol; 1999 Mar; 68(5-6):239-44. PubMed ID: 10416839
[TBL] [Abstract][Full Text] [Related]
10. Crystal structures of the binary and ternary complexes of 7 alpha-hydroxysteroid dehydrogenase from Escherichia coli.
Tanaka N; Nonaka T; Tanabe T; Yoshimoto T; Tsuru D; Mitsui Y
Biochemistry; 1996 Jun; 35(24):7715-30. PubMed ID: 8672472
[TBL] [Abstract][Full Text] [Related]
11. New insights into the substrate inhibition of human 17β-hydroxysteroid dehydrogenase type 1.
Li T; Song X; Stephen P; Yin H; Lin SX
J Steroid Biochem Mol Biol; 2023 Apr; 228():106246. PubMed ID: 36634828
[TBL] [Abstract][Full Text] [Related]
12. Amino acid substitution of arginine 80 in 17beta-hydroxysteroid dehydrogenase type 3 and its effect on NADPH cofactor binding and oxidation/reduction kinetics.
McKeever BM; Hawkins BK; Geissler WM; Wu L; Sheridan RP; Mosley RT; Andersson S
Biochim Biophys Acta; 2002 Nov; 1601(1):29-37. PubMed ID: 12429500
[TBL] [Abstract][Full Text] [Related]
13. 3D-structure of human estrogenic 17beta-HSD1: binding with various steroids.
Lin SX; Han Q; Azzi A; Zhu DW; Gangloff A; Campbell RL
J Steroid Biochem Mol Biol; 1999; 69(1-6):425-9. PubMed ID: 10419021
[TBL] [Abstract][Full Text] [Related]
14. First Structure-Activity Relationship of 17β-Hydroxysteroid Dehydrogenase Type 14 Nonsteroidal Inhibitors and Crystal Structures in Complex with the Enzyme.
Braun F; Bertoletti N; Möller G; Adamski J; Steinmetzer T; Salah M; Abdelsamie AS; van Koppen CJ; Heine A; Klebe G; Marchais-Oberwinkler S
J Med Chem; 2016 Dec; 59(23):10719-10737. PubMed ID: 27933965
[TBL] [Abstract][Full Text] [Related]
15. Pharmacophore modelling of 17beta-HSD1 enzyme based on active inhibitors and enzyme structure.
Karkola S; Alho-Richmond S; Wahala K
Mol Cell Endocrinol; 2009 Mar; 301(1-2):225-8. PubMed ID: 18822344
[TBL] [Abstract][Full Text] [Related]
16. Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.
Faucher F; Pereira de Jésus-Tran K; Cantin L; Luu-The V; Labrie F; Breton R
J Mol Biol; 2006 Dec; 364(4):747-63. PubMed ID: 17034817
[TBL] [Abstract][Full Text] [Related]
17. A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity.
Qiu W; Campbell RL; Gangloff A; Dupuis P; Boivin RP; Tremblay MR; Poirier D; Lin SX
FASEB J; 2002 Nov; 16(13):1829-31. PubMed ID: 12223444
[TBL] [Abstract][Full Text] [Related]
18. Pseudo-symmetry of C19 steroids, alternative binding orientations, and multispecificity in human estrogenic 17beta-hydroxysteroid dehydrogenase.
Gangloff A; Shi R; Nahoum V; Lin SX
FASEB J; 2003 Feb; 17(2):274-6. PubMed ID: 12490543
[TBL] [Abstract][Full Text] [Related]
19. Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.
Faucher F; Cantin L; Pereira de Jésus-Tran K; Lemieux M; Luu-The V; Labrie F; Breton R
J Mol Biol; 2007 Jun; 369(2):525-40. PubMed ID: 17442338
[TBL] [Abstract][Full Text] [Related]
20. Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues.
Qiu W; Zhou M; Labrie F; Lin SX
Mol Endocrinol; 2004 Jul; 18(7):1798-807. PubMed ID: 15087468
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
