156 related articles for article (PubMed ID: 14966133)
21. Design and synthesis of bisubstrate inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: overview and perspectives.
Fournier D; Poirier D; Mazumdar M; Lin SX
Eur J Med Chem; 2008 Nov; 43(11):2298-306. PubMed ID: 18372081
[TBL] [Abstract][Full Text] [Related]
22. Human dehydrogenase/reductase SDR family member 11 (DHRS11) and aldo-keto reductase 1C isoforms in comparison: Substrate and reaction specificity in the reduction of 11-keto-C
Endo S; Morikawa Y; Kudo Y; Suenami K; Matsunaga T; Ikari A; Hara A
J Steroid Biochem Mol Biol; 2020 May; 199():105586. PubMed ID: 31926269
[TBL] [Abstract][Full Text] [Related]
23. Binary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapy.
Mazumdar M; Fournier D; Zhu DW; Cadot C; Poirier D; Lin SX
Biochem J; 2009 Dec; 424(3):357-66. PubMed ID: 19929851
[TBL] [Abstract][Full Text] [Related]
24. New Insights into Human 17β-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor.
Bertoletti N; Braun F; Lepage M; Möller G; Adamski J; Heine A; Klebe G; Marchais-Oberwinkler S
J Med Chem; 2016 Jul; 59(14):6961-7. PubMed ID: 27362750
[TBL] [Abstract][Full Text] [Related]
25. Structural and biochemical investigations of the catalytic mechanism of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans.
Cobessi D; Tête-Favier F; Marchal S; Branlant G; Aubry A
J Mol Biol; 2000 Jun; 300(1):141-52. PubMed ID: 10864505
[TBL] [Abstract][Full Text] [Related]
26. Insights in 17beta-HSD1 enzyme kinetics and ligand binding by dynamic motion investigation.
Negri M; Recanatini M; Hartmann RW
PLoS One; 2010 Aug; 5(8):e12026. PubMed ID: 20706575
[TBL] [Abstract][Full Text] [Related]
27. Identification of fused 16β,17β-oxazinone-estradiol derivatives as a new family of non-estrogenic 17β-hydroxysteroid dehydrogenase type 1 inhibitors.
Maltais R; Trottier A; Delhomme A; Barbeau X; Lagüe P; Poirier D
Eur J Med Chem; 2015 Mar; 93():470-80. PubMed ID: 25728028
[TBL] [Abstract][Full Text] [Related]
28. Steroid dehydrogenase structures, mechanism of action, and disease.
Duax WL; Ghosh D; Pletnev V
Vitam Horm; 2000; 58():121-48. PubMed ID: 10668397
[TBL] [Abstract][Full Text] [Related]
29. Design, synthesis, and biological evaluation of (hydroxyphenyl)naphthalene and -quinoline derivatives: potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases.
Frotscher M; Ziegler E; Marchais-Oberwinkler S; Kruchten P; Neugebauer A; Fetzer L; Scherer C; Müller-Vieira U; Messinger J; Thole H; Hartmann RW
J Med Chem; 2008 Apr; 51(7):2158-69. PubMed ID: 18324762
[TBL] [Abstract][Full Text] [Related]
30. Molecular mechanisms of estrogen recognition and 17-keto reduction by human 17beta-hydroxysteroid dehydrogenase 1.
Ghosh D; Vihko P
Chem Biol Interact; 2001 Jan; 130-132(1-3):637-50. PubMed ID: 11306082
[TBL] [Abstract][Full Text] [Related]
31. Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: variants designed from the three-dimensional structure of the enzyme.
Huang YW; Pineau I; Chang HJ; Azzi A; Bellemare V; Laberge S; Lin SX
Mol Endocrinol; 2001 Nov; 15(11):2010-20. PubMed ID: 11682630
[TBL] [Abstract][Full Text] [Related]
32. Structural basis for inhibition of 17β-hydroxysteroid dehydrogenases by phytoestrogens: The case of fungal 17β-HSDcl.
Cassetta A; Stojan J; Krastanova I; Kristan K; Brunskole Švegelj M; Lamba D; Lanišnik Rižner T
J Steroid Biochem Mol Biol; 2017 Jul; 171():80-93. PubMed ID: 28259640
[TBL] [Abstract][Full Text] [Related]
33. Complementary deoxyribonucleic acid cloning and enzymatic characterization of a novel 17beta/3alpha-hydroxysteroid/retinoid short chain dehydrogenase/reductase.
Su J; Lin M; Napoli JL
Endocrinology; 1999 Nov; 140(11):5275-84. PubMed ID: 10537158
[TBL] [Abstract][Full Text] [Related]
34. Structure of 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase complexed with NADP+.
Bennett MJ; Schlegel BP; Jez JM; Penning TM; Lewis M
Biochemistry; 1996 Aug; 35(33):10702-11. PubMed ID: 8718859
[TBL] [Abstract][Full Text] [Related]
35. Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family.
Tanaka N; Nonaka T; Nakanishi M; Deyashiki Y; Hara A; Mitsui Y
Structure; 1996 Jan; 4(1):33-45. PubMed ID: 8805511
[TBL] [Abstract][Full Text] [Related]
36. Structures of complexes of type 5 17β-hydroxysteroid dehydrogenase with structurally diverse inhibitors: insights into the conformational changes upon inhibitor binding.
Amano Y; Yamaguchi T; Niimi T; Sakashita H
Acta Crystallogr D Biol Crystallogr; 2015 Apr; 71(Pt 4):918-27. PubMed ID: 25849402
[TBL] [Abstract][Full Text] [Related]
37. Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17beta-hydroxysteroid dehydrogenase. C-18/c-19 steroid discrimination and enzyme-induced strain.
Han Q; Campbell RL; Gangloff A; Huang YW; Lin SX
J Biol Chem; 2000 Jan; 275(2):1105-11. PubMed ID: 10625652
[TBL] [Abstract][Full Text] [Related]
38. Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase.
Bennett MJ; Albert RH; Jez JM; Ma H; Penning TM; Lewis M
Structure; 1997 Jun; 5(6):799-812. PubMed ID: 9261071
[TBL] [Abstract][Full Text] [Related]
39. Combined Biophysical Chemistry Reveals a New Covalent Inhibitor with a Low-Reactivity Alkyl Halide.
Li T; Maltais R; Poirier D; Lin SX
J Phys Chem Lett; 2018 Sep; 9(18):5275-5280. PubMed ID: 30148957
[TBL] [Abstract][Full Text] [Related]
40. Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.
Schuster D; Nashev LG; Kirchmair J; Laggner C; Wolber G; Langer T; Odermatt A
J Med Chem; 2008 Jul; 51(14):4188-99. PubMed ID: 18533708
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]