BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 14967036)

  • 1. Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity.
    Aitken SM; Kirsch JF
    Biochemistry; 2004 Feb; 43(7):1963-71. PubMed ID: 14967036
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetics of the yeast cystathionine beta-synthase forward and reverse reactions: continuous assays and the equilibrium constant for the reaction.
    Aitken SM; Kirsch JF
    Biochemistry; 2003 Jan; 42(2):571-8. PubMed ID: 12525186
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of residues Lys112, Glu136, His138, Gly247, Tyr248, and Asp249 in the active site of yeast cystathionine beta-synthase.
    Lodha PH; Shadnia H; Woodhouse CM; Wright JS; Aitken SM
    Biochem Cell Biol; 2009 Jun; 87(3):531-40. PubMed ID: 19448746
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Investigation of the functional contributions of invariant serine residues in yeast mevalonate diphosphate decarboxylase.
    Krepkiy DV; Miziorko HM
    Biochemistry; 2005 Feb; 44(7):2671-7. PubMed ID: 15709780
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Residue N84 of yeast cystathionine beta-synthase is a determinant of reaction specificity.
    Lodha PH; Hopwood EM; Manders AL; Aitken SM
    Biochim Biophys Acta; 2010 Jul; 1804(7):1424-31. PubMed ID: 20176145
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
    Sandmark J; Eliot AC; Famm K; Schneider G; Kirsch JF
    Biochemistry; 2004 Feb; 43(5):1213-22. PubMed ID: 14756557
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of the heme and pyridoxal phosphate cofactors of human cystathionine beta-synthase reveals nonequivalent active sites.
    Taoka S; West M; Banerjee R
    Biochemistry; 1999 Mar; 38(9):2738-44. PubMed ID: 10052944
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Visualization of PLP-bound intermediates in hemeless variants of human cystathionine beta-synthase: evidence that lysine 119 is a general base.
    Evande R; Ojha S; Banerjee R
    Arch Biochem Biophys; 2004 Jul; 427(2):188-96. PubMed ID: 15196993
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinetic characterization of recombinant human cystathionine beta-synthase purified from E. coli.
    Belew MS; Quazi FI; Willmore WG; Aitken SM
    Protein Expr Purif; 2009 Apr; 64(2):139-45. PubMed ID: 19010420
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Solvent-accessible cysteines in human cystathionine beta-synthase: crucial role of cysteine 431 in S-adenosyl-L-methionine binding.
    Frank N; Kery V; Maclean KN; Kraus JP
    Biochemistry; 2006 Sep; 45(36):11021-9. PubMed ID: 16953589
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein.
    Banerjee R; Zou CG
    Arch Biochem Biophys; 2005 Jan; 433(1):144-56. PubMed ID: 15581573
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BetaQ114N and betaT110V mutations reveal a critically important role of the substrate alpha-carboxylate site in the reaction specificity of tryptophan synthase.
    Blumenstein L; Domratcheva T; Niks D; Ngo H; Seidel R; Dunn MF; Schlichting I
    Biochemistry; 2007 Dec; 46(49):14100-16. PubMed ID: 18004874
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alanine scanning mutagenesis of the testosterone binding site of rat 3 alpha-hydroxysteroid dehydrogenase demonstrates contact residues influence the rate-determining step.
    Heredia VV; Cooper WC; Kruger RG; Jin Y; Penning TM
    Biochemistry; 2004 May; 43(19):5832-41. PubMed ID: 15134457
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of changes in three catalytic residues on the relative stabilities of some of the intermediates and transition states in the citrate synthase reaction.
    Kurz LC; Nakra T; Stein R; Plungkhen W; Riley M; Hsu F; Drysdale GR
    Biochemistry; 1998 Jul; 37(27):9724-37. PubMed ID: 9657685
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interconversion of a pair of active-site residues in Escherichia coli cystathionine gamma-synthase, E. coli cystathionine beta-lyase, and Saccharomyces cerevisiae cystathionine gamma-lyase and development of tools for the investigation of their mechanisms and reaction specificity.
    Farsi A; Lodha PH; Skanes JE; Los H; Kalidindi N; Aitken SM
    Biochem Cell Biol; 2009 Apr; 87(2):445-57. PubMed ID: 19370061
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Binding of pyridoxal 5'-phosphate to the heme protein human cystathionine beta-synthase.
    Kery V; Poneleit L; Meyer JD; Manning MC; Kraus JP
    Biochemistry; 1999 Mar; 38(9):2716-24. PubMed ID: 10052942
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of the side-chain hydroxyl moieties of residues Y56, Y111, Y238, Y338, and S339 as determinants of specificity in E. coli cystathionine β-lyase.
    Lodha PH; Aitken SM
    Biochemistry; 2011 Nov; 50(45):9876-85. PubMed ID: 21958132
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tryptophan synthase mutations that alter cofactor chemistry lead to mechanism-based inactivation.
    Jhee KH; McPhie P; Ro HS; Miles EW
    Biochemistry; 1998 Oct; 37(41):14591-604. PubMed ID: 9772188
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase.
    Wise EL; Yew WS; Akana J; Gerlt JA; Rayment I
    Biochemistry; 2005 Feb; 44(6):1816-23. PubMed ID: 15697207
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Allosteric regulation of substrate channeling in tryptophan synthase: modulation of the L-serine reaction in stage I of the beta-reaction by alpha-site ligands.
    Ngo H; Kimmich N; Harris R; Niks D; Blumenstein L; Kulik V; Barends TR; Schlichting I; Dunn MF
    Biochemistry; 2007 Jul; 46(26):7740-53. PubMed ID: 17559232
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.