937 related articles for article (PubMed ID: 14974085)
1. Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation.
Fragale A; Tartaglia M; Wu J; Gelb BD
Hum Mutat; 2004 Mar; 23(3):267-77. PubMed ID: 14974085
[TBL] [Abstract][Full Text] [Related]
2. Requirement of SHP2 binding to Grb2-associated binder-1 for mitogen-activated protein kinase activation in response to lysophosphatidic acid and epidermal growth factor.
Cunnick JM; Dorsey JF; Munoz-Antonia T; Mei L; Wu J
J Biol Chem; 2000 May; 275(18):13842-8. PubMed ID: 10788507
[TBL] [Abstract][Full Text] [Related]
3. Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia.
Bentires-Alj M; Paez JG; David FS; Keilhack H; Halmos B; Naoki K; Maris JM; Richardson A; Bardelli A; Sugarbaker DJ; Richards WG; Du J; Girard L; Minna JD; Loh ML; Fisher DE; Velculescu VE; Vogelstein B; Meyerson M; Sellers WR; Neel BG
Cancer Res; 2004 Dec; 64(24):8816-20. PubMed ID: 15604238
[TBL] [Abstract][Full Text] [Related]
4. Role of the Grb2-associated binder 1/SHP-2 interaction in cell growth and transformation.
Holgado-Madruga M; Wong AJ
Cancer Res; 2004 Mar; 64(6):2007-15. PubMed ID: 15026337
[TBL] [Abstract][Full Text] [Related]
5. A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.
Yart A; Laffargue M; Mayeux P; Chretien S; Peres C; Tonks N; Roche S; Payrastre B; Chap H; Raynal P
J Biol Chem; 2001 Mar; 276(12):8856-64. PubMed ID: 11134009
[TBL] [Abstract][Full Text] [Related]
6. Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2.
Cunnick JM; Mei L; Doupnik CA; Wu J
J Biol Chem; 2001 Jun; 276(26):24380-7. PubMed ID: 11323411
[TBL] [Abstract][Full Text] [Related]
7. Activation of gp130 transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes.
Nakaoka Y; Nishida K; Fujio Y; Izumi M; Terai K; Oshima Y; Sugiyama S; Matsuda S; Koyasu S; Yamauchi-Takihara K; Hirano T; Kawase I; Hirota H
Circ Res; 2003 Aug; 93(3):221-9. PubMed ID: 12855672
[TBL] [Abstract][Full Text] [Related]
8. PTPN11 mutations in Noonan syndrome type I: detection of recurrent mutations in exons 3 and 13.
Maheshwari M; Belmont J; Fernbach S; Ho T; Molinari L; Yakub I; Yu F; Combes A; Towbin J; Craigen WJ; Gibbs R
Hum Mutat; 2002 Oct; 20(4):298-304. PubMed ID: 12325025
[TBL] [Abstract][Full Text] [Related]
9. Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature.
De Rocca Serra-Nédélec A; Edouard T; Tréguer K; Tajan M; Araki T; Dance M; Mus M; Montagner A; Tauber M; Salles JP; Valet P; Neel BG; Raynal P; Yart A
Proc Natl Acad Sci U S A; 2012 Mar; 109(11):4257-62. PubMed ID: 22371576
[TBL] [Abstract][Full Text] [Related]
10. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
Bode JG; Schweigart J; Kehrmann J; Ehlting C; Schaper F; Heinrich PC; Häussinger D
J Immunol; 2003 Jul; 171(1):257-66. PubMed ID: 12817006
[TBL] [Abstract][Full Text] [Related]
11. Regulation of the mitogen-activated protein kinase signaling pathway by SHP2.
Cunnick JM; Meng S; Ren Y; Desponts C; Wang HG; Djeu JY; Wu J
J Biol Chem; 2002 Mar; 277(11):9498-504. PubMed ID: 11779868
[TBL] [Abstract][Full Text] [Related]
12. SH2 domain containing protein tyrosine phosphatase 2 regulates concanavalin A-dependent secretion and activation of matrix metalloproteinase 2 via the extracellular signal-regulated kinase and p38 pathways.
Ruhul Amin AR; Oo ML; Senga T; Suzuki N; Feng GS; Hamaguchi M
Cancer Res; 2003 Oct; 63(19):6334-9. PubMed ID: 14559821
[TBL] [Abstract][Full Text] [Related]
13. A role for Grb2-associated binder-1 in growth hormone signaling.
Kim SO; Loesch K; Wang X; Jiang J; Mei L; Cunnick JM; Wu J; Frank SJ
Endocrinology; 2002 Dec; 143(12):4856-67. PubMed ID: 12446613
[TBL] [Abstract][Full Text] [Related]
14. Participation of both Gab1 and Gab2 in the activation of the ERK/MAPK pathway by epidermal growth factor.
Meng S; Chen Z; Munoz-Antonia T; Wu J
Biochem J; 2005 Oct; 391(Pt 1):143-51. PubMed ID: 15952937
[TBL] [Abstract][Full Text] [Related]
15. Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation.
Hadari YR; Kouhara H; Lax I; Schlessinger J
Mol Cell Biol; 1998 Jul; 18(7):3966-73. PubMed ID: 9632781
[TBL] [Abstract][Full Text] [Related]
16. Noonan syndrome mutation Q79R in Shp2 increases proliferation of valve primordia mesenchymal cells via extracellular signal-regulated kinase 1/2 signaling.
Krenz M; Yutzey KE; Robbins J
Circ Res; 2005 Oct; 97(8):813-20. PubMed ID: 16166557
[TBL] [Abstract][Full Text] [Related]
17. The SH2 tyrosine phosphatase shp2 is required for mammalian limb development.
Saxton TM; Ciruna BG; Holmyard D; Kulkarni S; Harpal K; Rossant J; Pawson T
Nat Genet; 2000 Apr; 24(4):420-3. PubMed ID: 10742110
[TBL] [Abstract][Full Text] [Related]
18. Identification of epidermal growth factor receptor- Grb2-associated binder-1-SHP-2 complex formation and its functional loss during neoplastic cell progression.
Kameda H; Risinger JI; Han BB; Baek SJ; Barrett JC; Glasgow WC; Eling TE
Cell Growth Differ; 2001 Jun; 12(6):307-18. PubMed ID: 11432805
[TBL] [Abstract][Full Text] [Related]
19. Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome.
Nakamura T; Colbert M; Krenz M; Molkentin JD; Hahn HS; Dorn GW; Robbins J
J Clin Invest; 2007 Aug; 117(8):2123-32. PubMed ID: 17641779
[TBL] [Abstract][Full Text] [Related]
20. Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor.
Ren Y; Meng S; Mei L; Zhao ZJ; Jove R; Wu J
J Biol Chem; 2004 Feb; 279(9):8497-505. PubMed ID: 14665621
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
