BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 14979713)

  • 1. A nuclear localization sequence endows human pancreatic ribonuclease with cytotoxic activity.
    Bosch M; Benito A; Ribó M; Puig T; Beaumelle B; Vilanova M
    Biochemistry; 2004 Mar; 43(8):2167-77. PubMed ID: 14979713
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Generation of new cytotoxic human ribonuclease variants directed to the nucleus.
    Vert A; Castro J; Ruiz-Martínez S; Tubert P; Escribano D; Ribó M; Vilanova M; Benito A
    Mol Pharm; 2012 Oct; 9(10):2894-902. PubMed ID: 22957849
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tandemization endows bovine pancreatic ribonuclease with cytotoxic activity.
    Leich F; Köditz J; Ulbrich-Hofman R; Arnold U
    J Mol Biol; 2006 May; 358(5):1305-13. PubMed ID: 16580680
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A cytotoxic ribonuclease variant with a discontinuous nuclear localization signal constituted by basic residues scattered over three areas of the molecule.
    Rodríguez M; Benito A; Tubert P; Castro J; Ribó M; Beaumelle B; Vilanova M
    J Mol Biol; 2006 Jul; 360(3):548-57. PubMed ID: 16780873
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of shape-complementarity markers to create cytotoxic variants of ribonuclease A.
    Rutkoski TJ; Kurten EL; Mitchell JC; Raines RT
    J Mol Biol; 2005 Nov; 354(1):41-54. PubMed ID: 16188273
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytotoxicity of bovine seminal ribonuclease: monomer versus dimer.
    Lee JE; Raines RT
    Biochemistry; 2005 Dec; 44(48):15760-7. PubMed ID: 16313179
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The nuclear transport capacity of a human-pancreatic ribonuclease variant is critical for its cytotoxicity.
    Tubert P; Rodríguez M; Ribó M; Benito A; Vilanova M
    Invest New Drugs; 2011 Oct; 29(5):811-7. PubMed ID: 20352290
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increasing the potency of a cytotoxin with an arginine graft.
    Fuchs SM; Rutkoski TJ; Kung VM; Groeschl RT; Raines RT
    Protein Eng Des Sel; 2007 Oct; 20(10):505-9. PubMed ID: 17954521
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytotoxicity of human RNase-based immunotoxins requires cytosolic access and resistance to ribonuclease inhibition.
    Erickson HA; Jund MD; Pennell CA
    Protein Eng Des Sel; 2006 Jan; 19(1):37-45. PubMed ID: 16243897
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An importin alpha/beta-recognized bipartite nuclear localization signal mediates targeting of the human herpes simplex virus type 1 DNA polymerase catalytic subunit pUL30 to the nucleus.
    Alvisi G; Musiani D; Jans DA; Ripalti A
    Biochemistry; 2007 Aug; 46(32):9155-63. PubMed ID: 17640102
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Two nuclear localization signals required for transport from the cytosol to the nucleus of externally added FGF-1 translocated into cells.
    Wesche J; Małecki J; Wiedłocha A; Ehsani M; Marcinkowska E; Nilsen T; Olsnes S
    Biochemistry; 2005 Apr; 44(16):6071-80. PubMed ID: 15835896
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear and nucleolar localization signals and their targeting function in phosphatidylinositol 4-kinase PI4K230.
    Kakuk A; Friedländer E; Vereb G; Lisboa D; Bagossi P; Tóth G; Gergely P; Vereb G
    Exp Cell Res; 2008 Aug; 314(13):2376-88. PubMed ID: 18585705
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Silencing an inhibitor unleashes a cytotoxic enzyme.
    Dickson KA; Raines RT
    Biochemistry; 2009 Jun; 48(23):5051-3. PubMed ID: 19402708
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nuclear transport of Ras-associated tumor suppressor proteins: different transport receptor binding specificities for arginine-rich nuclear targeting signals.
    Kumari G; Singhal PK; Rao MR; Mahalingam S
    J Mol Biol; 2007 Apr; 367(5):1294-311. PubMed ID: 17320110
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A ribonuclease A variant with low catalytic activity but high cytotoxicity.
    Bretscher LE; Abel RL; Raines RT
    J Biol Chem; 2000 Apr; 275(14):9893-6. PubMed ID: 10744660
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nuclear import and export signals are essential for proper cellular trafficking and function of ZIC3.
    Bedard JE; Purnell JD; Ware SM
    Hum Mol Genet; 2007 Jan; 16(2):187-98. PubMed ID: 17185387
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High-level soluble production and characterization of porcine ribonuclease inhibitor.
    Klink TA; Vicentini AM; Hofsteenge J; Raines RT
    Protein Expr Purif; 2001 Jul; 22(2):174-9. PubMed ID: 11437592
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Endowing human pancreatic ribonuclease with toxicity for cancer cells.
    Leland PA; Staniszewski KE; Kim BM; Raines RT
    J Biol Chem; 2001 Nov; 276(46):43095-102. PubMed ID: 11555655
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Construction of Highly Stable Cytotoxic Nuclear-Directed Ribonucleases.
    Roura Padrosa D; Castro J; Romero-Casañas A; Ribó M; Vilanova M; Benito A
    Molecules; 2018 Dec; 23(12):. PubMed ID: 30544927
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transport of galectin-3 between the nucleus and cytoplasm. I. Conditions and signals for nuclear import.
    Davidson PJ; Li SY; Lohse AG; Vandergaast R; Verde E; Pearson A; Patterson RJ; Wang JL; Arnoys EJ
    Glycobiology; 2006 Jul; 16(7):602-11. PubMed ID: 16473835
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.