BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 14980693)

  • 1. Synthesis, topoisomerase I inhibition and structure-activity relationship study of 2,4,6-trisubstituted pyridine derivatives.
    Zhao LX; Moon YS; Basnet A; Kim EK; Jahng Y; Park JG; Jeong TC; Cho WJ; Choi SU; Lee CO; Lee SY; Lee CS; Lee ES
    Bioorg Med Chem Lett; 2004 Mar; 14(5):1333-7. PubMed ID: 14980693
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2,4,6-Trisubstituted pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
    Basnet A; Thapa P; Karki R; Na Y; Jahng Y; Jeong BS; Jeong TC; Lee CS; Lee ES
    Bioorg Med Chem; 2007 Jul; 15(13):4351-9. PubMed ID: 17493824
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2,6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure-activity relationship, and docking study.
    Basnet A; Thapa P; Karki R; Choi H; Choi JH; Yun M; Jeong BS; Jahng Y; Na Y; Cho WJ; Kwon Y; Lee CS; Lee ES
    Bioorg Med Chem Lett; 2010 Jan; 20(1):42-7. PubMed ID: 19954977
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-Thienyl-4-furyl-6-aryl pyridine derivatives: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.
    Thapa P; Karki R; Thapa U; Jahng Y; Jung MJ; Nam JM; Na Y; Kwon Y; Lee ES
    Bioorg Med Chem; 2010 Jan; 18(1):377-86. PubMed ID: 19939682
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of 2,6-diaryl-substituted pyridines and their antitumor activities.
    Son JK; Zhao LX; Basnet A; Thapa P; Karki R; Na Y; Jahng Y; Jeong TC; Jeong BS; Lee CS; Lee ES
    Eur J Med Chem; 2008 Apr; 43(4):675-82. PubMed ID: 17673337
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines.
    Kadayat TM; Song C; Shin S; Magar TB; Bist G; Shrestha A; Thapa P; Na Y; Kwon Y; Lee ES
    Bioorg Med Chem; 2015 Jul; 23(13):3499-512. PubMed ID: 26022080
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
    Thapa P; Karki R; Choi H; Choi JH; Yun M; Jeong BS; Jung MJ; Nam JM; Na Y; Cho WJ; Kwon Y; Lee ES
    Bioorg Med Chem; 2010 Mar; 18(6):2245-2254. PubMed ID: 20188578
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and synthesis of novel 2,4-diaryl-5H-indeno[1,2-b]pyridine derivatives, and their evaluation of topoisomerase inhibitory activity and cytotoxicity.
    Kadayat TM; Park C; Jun KY; Magar TB; Bist G; Yoo HY; Kwon Y; Lee ES
    Bioorg Med Chem; 2015 Jan; 23(1):160-73. PubMed ID: 25481396
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines.
    Karki R; Thapa P; Kang MJ; Jeong TC; Nam JM; Kim HL; Na Y; Cho WJ; Kwon Y; Lee ES
    Bioorg Med Chem; 2010 May; 18(9):3066-77. PubMed ID: 20392646
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dihydroxylated 2,4,6-triphenyl pyridines: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.
    Karki R; Thapa P; Yoo HY; Kadayat TM; Park PH; Na Y; Lee E; Jeon KH; Cho WJ; Choi H; Kwon Y; Lee ES
    Eur J Med Chem; 2012 Mar; 49():219-28. PubMed ID: 22318164
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
    Thapa U; Thapa P; Karki R; Yun M; Choi JH; Jahng Y; Lee E; Jeon KH; Na Y; Ha EM; Cho WJ; Kwon Y; Lee ES
    Eur J Med Chem; 2011 Aug; 46(8):3201-9. PubMed ID: 21601964
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Substituted 2,5'-Bi-1H-benzimidazoles: topoisomerase I inhibition and cytotoxicity.
    Kim JS; Gatto B; Yu C; Liu A; Liu LF; LaVoie EJ
    J Med Chem; 1996 Feb; 39(4):992-8. PubMed ID: 8632422
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, cytotoxic activities and structure-activity relationships of topoisomerase I inhibitors: indolizinoquinoline-5,12-dione derivatives.
    Cheng Y; An LK; Wu N; Wang XD; Bu XZ; Huang ZS; Gu LQ
    Bioorg Med Chem; 2008 Apr; 16(8):4617-25. PubMed ID: 18296054
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors.
    Dallavalle S; Gattinoni S; Mazzini S; Scaglioni L; Merlini L; Tinelli S; Beretta GL; Zunino F
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1484-9. PubMed ID: 18248813
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxiranylmethyloxy or thiiranylmethyloxy-azaxanthones and -acridone analogues as potential topoisomerase I inhibitors.
    Cho HJ; Jung MJ; Kwon Y; Na Y
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6766-9. PubMed ID: 19836231
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of nitrated indenoisoquinolines as topoisomerase I inhibitors.
    Morrell A; Antony S; Kohlhagen G; Pommier Y; Cushman M
    Bioorg Med Chem Lett; 2004 Jul; 14(14):3659-63. PubMed ID: 15203138
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridines.
    Karki R; Song C; Kadayat TM; Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Bioorg Med Chem; 2015 Jul; 23(13):3638-54. PubMed ID: 25936262
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitory activities against topoisomerase I and II by polyhydroxybenzoyl amide derivatives and their structure-activity relationship.
    Abdel-Aziz M; Matsuda K; Otsuka M; Uyeda M; Okawara T; Suzuki K
    Bioorg Med Chem Lett; 2004 Apr; 14(7):1669-72. PubMed ID: 15026047
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Convenient synthesis of indeno[1,2-c]isoquinolines as constrained forms of 3-arylisoquinolines and docking study of a topoisomerase I inhibitor into DNA-topoisomerase I complex.
    Van HT; Le QM; Lee KY; Lee ES; Kwon Y; Kim TS; Le TN; Lee SH; Cho WJ
    Bioorg Med Chem Lett; 2007 Nov; 17(21):5763-7. PubMed ID: 17827007
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological activities of topoisomerase I inhibitors, 6-arylmethylamino analogues of edotecarin.
    Sunami S; Nishimura T; Nishimura I; Ito S; Arakawa H; Ohkubo M
    J Med Chem; 2009 May; 52(10):3225-37. PubMed ID: 19397324
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.