BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 14981238)

  • 1. Predicted 3D structure for the human beta 2 adrenergic receptor and its binding site for agonists and antagonists.
    Freddolino PL; Kalani MY; Vaidehi N; Floriano WB; Hall SE; Trabanino RJ; Kam VW; Goddard WA
    Proc Natl Acad Sci U S A; 2004 Mar; 101(9):2736-41. PubMed ID: 14981238
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biochemistry. Signaling across the cell membrane.
    Ranganathan R
    Science; 2007 Nov; 318(5854):1253-4. PubMed ID: 18033872
    [No Abstract]   [Full Text] [Related]  

  • 3. Dynamic behavior of fully solvated beta2-adrenergic receptor, embedded in the membrane with bound agonist or antagonist.
    Spijker P; Vaidehi N; Freddolino PL; Hilbers PA; Goddard WA
    Proc Natl Acad Sci U S A; 2006 Mar; 103(13):4882-7. PubMed ID: 16551744
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for ligand binding and specificity in adrenergic receptors: implications for GPCR-targeted drug discovery.
    Huber T; Menon S; Sakmar TP
    Biochemistry; 2008 Oct; 47(42):11013-23. PubMed ID: 18821775
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Use of the X-ray structure of the Beta2-adrenergic receptor for drug discovery.
    Topiol S; Sabio M
    Bioorg Med Chem Lett; 2008 Mar; 18(5):1598-602. PubMed ID: 18243704
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.
    Rosenbaum DM; Cherezov V; Hanson MA; Rasmussen SG; Thian FS; Kobilka TS; Choi HJ; Yao XJ; Weis WI; Stevens RC; Kobilka BK
    Science; 2007 Nov; 318(5854):1266-73. PubMed ID: 17962519
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Three-dimensional models for agonist and antagonist complexes with beta 2 adrenergic receptor.
    Kontoyianni M; DeWeese C; Penzotti JE; Lybrand TP
    J Med Chem; 1996 Oct; 39(22):4406-20. PubMed ID: 8893835
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Three-dimensional models for beta-adrenergic receptor complexes with agonists and antagonists.
    Furse KE; Lybrand TP
    J Med Chem; 2003 Oct; 46(21):4450-62. PubMed ID: 14521408
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ligand entry and exit pathways in the beta2-adrenergic receptor.
    Wang T; Duan Y
    J Mol Biol; 2009 Oct; 392(4):1102-15. PubMed ID: 19665031
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential signaling of the endogenous agonists at the beta2-adrenergic receptor.
    Reiner S; Ambrosio M; Hoffmann C; Lohse MJ
    J Biol Chem; 2010 Nov; 285(46):36188-98. PubMed ID: 20837485
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-Based Prediction of G-Protein-Coupled Receptor Ligand Function: A β-Adrenoceptor Case Study.
    Kooistra AJ; Leurs R; de Esch IJ; de Graaf C
    J Chem Inf Model; 2015 May; 55(5):1045-61. PubMed ID: 25848966
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probes.
    Isin B; Estiu G; Wiest O; Oltvai ZN
    PLoS One; 2012; 7(12):e50186. PubMed ID: 23300522
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GPCRs through the keyhole: the role of protein flexibility in ligand binding to β-adrenoceptors.
    Emtage AL; Mistry SN; Fischer PM; Kellam B; Laughton CA
    J Biomol Struct Dyn; 2017 Sep; 35(12):2604-2619. PubMed ID: 27532213
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The unique nature of the serine interactions for alpha 1-adrenergic receptor agonist binding and activation.
    Hwa J; Perez DM
    J Biol Chem; 1996 Mar; 271(11):6322-7. PubMed ID: 8626427
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recent advances in structure, binding sites with ligands and pharmacological function of beta-adrenoceptors obtained by molecular biology and molecular modeling.
    Nagatomo T; Koike K
    Life Sci; 2000; 66(25):2419-26. PubMed ID: 10894084
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes.
    Katritch V; Reynolds KA; Cherezov V; Hanson MA; Roth CB; Yeager M; Abagyan R
    J Mol Recognit; 2009; 22(4):307-18. PubMed ID: 19353579
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular modeling of A1 and A2A adenosine receptors: comparison of rhodopsin- and beta2-adrenergic-based homology models through the docking studies.
    Yuzlenko O; Kieć-Kononowicz K
    J Comput Chem; 2009 Jan; 30(1):14-32. PubMed ID: 18496794
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Binding pockets of the beta(1)- and beta(2)-adrenergic receptors for subtype-selective agonists.
    Isogaya M; Sugimoto Y; Tanimura R; Tanaka R; Kikkawa H; Nagao T; Kurose H
    Mol Pharmacol; 1999 Nov; 56(5):875-85. PubMed ID: 10531390
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prediction of structure and function of G protein-coupled receptors.
    Vaidehi N; Floriano WB; Trabanino R; Hall SE; Freddolino P; Choi EJ; Zamanakos G; Goddard WA
    Proc Natl Acad Sci U S A; 2002 Oct; 99(20):12622-7. PubMed ID: 12351677
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A model of the adrenergic beta-2 receptor and binding sites for agonist and antagonist.
    Lewell XQ
    Drug Des Discov; 1992; 9(1):29-48. PubMed ID: 1360841
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.