These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 14982413)

  • 1. New tools for molecular imaging of redox metabolism: development of a fluorogenic probe for 3 alpha-hydroxysteroid dehydrogenases.
    Yee DJ; Balsanek V; Sames D
    J Am Chem Soc; 2004 Mar; 126(8):2282-3. PubMed ID: 14982413
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dissection of the physiological interconversion of 5alpha-DHT and 3alpha-diol by rat 3alpha-HSD via transient kinetics shows that the chemical step is rate-determining: effect of mutating cofactor and substrate-binding pocket residues on catalysis.
    Heredia VV; Penning TM
    Biochemistry; 2004 Sep; 43(38):12028-37. PubMed ID: 15379543
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Androgen inactivation and steroid-converting enzyme expression in abdominal adipose tissue in men.
    Blouin K; Richard C; Brochu G; Hould FS; Lebel S; Marceau S; Biron S; Luu-The V; Tchernof A
    J Endocrinol; 2006 Dec; 191(3):637-49. PubMed ID: 17170221
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Steroid 5alpha-reductases and 3alpha-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism.
    Jin Y; Penning TM
    Best Pract Res Clin Endocrinol Metab; 2001 Mar; 15(1):79-94. PubMed ID: 11469812
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular cloning of a novel type of rat cytoplasmic 17beta-hydroxysteroid dehydrogenase distinct from the type 5 isozyme.
    Ishikura S; Matsumoto K; Sanai M; Horie K; Matsunaga T; Tajima K; El-Kabbani O; Hara A
    J Biochem; 2006 Jun; 139(6):1053-63. PubMed ID: 16788056
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alanine scanning mutagenesis of the testosterone binding site of rat 3 alpha-hydroxysteroid dehydrogenase demonstrates contact residues influence the rate-determining step.
    Heredia VV; Cooper WC; Kruger RG; Jin Y; Penning TM
    Biochemistry; 2004 May; 43(19):5832-41. PubMed ID: 15134457
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chiral inversion of RS-8359: a selective and reversible MAO-A inhibitor via oxido-reduction of keto-alcohol.
    Itoh K; Hoshino K; Endo A; Asakawa T; Yamakami K; Noji C; Kosaka T; Tanaka Y
    Chirality; 2006 Sep; 18(9):698-706. PubMed ID: 16823812
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fluorogenic metabolic probes for direct activity readout of redox enzymes: Selective measurement of human AKR1C2 in living cells.
    Yee DJ; Balsanek V; Bauman DR; Penning TM; Sames D
    Proc Natl Acad Sci U S A; 2006 Sep; 103(36):13304-9. PubMed ID: 16938874
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design of optical switches as metabolic indicators: new fluorogenic probes for monoamine oxidases (MAO A and B).
    Chen G; Yee DJ; Gubernator NG; Sames D
    J Am Chem Soc; 2005 Apr; 127(13):4544-5. PubMed ID: 15796498
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rat NAD+-dependent 3alpha-hydroxysteroid dehydrogenase (AKR1C17): a member of the aldo-keto reductase family highly expressed in kidney cytosol.
    Sanai M; Endo S; Matsunaga T; Ishikura S; Tajima K; El-Kabbani O; Hara A
    Arch Biochem Biophys; 2007 Aug; 464(1):122-9. PubMed ID: 17475203
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) activity of human lung microsomes by genistein, daidzein, coumestrol and C(18)-, C(19)- and C(21)-hydroxysteroids and ketosteroids.
    Blomquist CH; Lima PH; Hotchkiss JR
    Steroids; 2005 Jul; 70(8):507-14. PubMed ID: 15894034
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expanding the use of fluorogenic enzyme reporter substrates to imaging metabolic flux changes: the activity measurement of 5α-steroid reductase in intact mammalian cells.
    Rodriguez PC; Yee DJ; Sames D
    ACS Chem Biol; 2010 Nov; 5(11):1045-52. PubMed ID: 20863068
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Harnessing functional plasticity of enzymes: a fluorogenic probe for imaging 17beta-HSD10 dehydrogenase, an enzyme involved in Alzheimer's and Parkinson's diseases.
    Froemming MK; Sames D
    J Am Chem Soc; 2007 Nov; 129(46):14518-22. PubMed ID: 17958419
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Understanding oligomerization in 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni: an in silico approach and evidence for an active protein.
    Hoffmann F; Sotriffer C; Evers A; Xiong G; Maser E
    J Biotechnol; 2007 Mar; 129(1):131-9. PubMed ID: 17258342
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The effect of allelic variation in aldo-keto reductase 1C2 on the in vitro metabolism of dihydrotestosterone.
    Takahashi RH; Grigliatti TA; Reid RE; Riggs KW
    J Pharmacol Exp Ther; 2009 Jun; 329(3):1032-9. PubMed ID: 19258517
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human 3α-hydroxysteroid dehydrogenase type 3: structural clues of 5α-DHT reverse binding and enzyme down-regulation decreasing MCF7 cell growth.
    Zhang B; Hu XJ; Wang XQ; Thériault JF; Zhu DW; Shang P; Labrie F; Lin SX
    Biochem J; 2016 Apr; 473(8):1037-46. PubMed ID: 26929402
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biocatalytic strategies for the asymmetric synthesis of alpha-hydroxy ketones.
    Hoyos P; Sinisterra JV; Molinari F; Alcántara AR; Domínguez de María P
    Acc Chem Res; 2010 Feb; 43(2):288-99. PubMed ID: 19908854
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recent advances in the biocatalytic reduction of ketones and oxidation of sec-alcohols.
    Kroutil W; Mang H; Edegger K; Faber K
    Curr Opin Chem Biol; 2004 Apr; 8(2):120-6. PubMed ID: 15062771
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multiple steps determine the overall rate of the reduction of 5alpha-dihydrotestosterone catalyzed by human type 3 3alpha-hydroxysteroid dehydrogenase: implications for the elimination of androgens.
    Jin Y; Penning TM
    Biochemistry; 2006 Oct; 45(43):13054-63. PubMed ID: 17059222
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Electronic effects of para-substitution on acetophenones in the reaction of rat liver 3alpha-hydroxysteroid dehydrogenase.
    Uwai K; Konno N; Yasuta Y; Takeshita M
    Bioorg Med Chem; 2008 Feb; 16(3):1084-9. PubMed ID: 18006320
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.