171 related articles for article (PubMed ID: 14985071)
1. Simvastatin reduces human atrial myofibroblast proliferation independently of cholesterol lowering via inhibition of RhoA.
Porter KE; Turner NA; O'Regan DJ; Balmforth AJ; Ball SG
Cardiovasc Res; 2004 Mar; 61(4):745-55. PubMed ID: 14985071
[TBL] [Abstract][Full Text] [Related]
2. Tumor necrosis factor alpha induces human atrial myofibroblast proliferation, invasion and MMP-9 secretion: inhibition by simvastatin.
Porter KE; Turner NA; O'Regan DJ; Ball SG
Cardiovasc Res; 2004 Dec; 64(3):507-15. PubMed ID: 15537504
[TBL] [Abstract][Full Text] [Related]
3. Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation.
Lee MH; Cho YS; Han YM
Stem Cells; 2007 Jul; 25(7):1654-63. PubMed ID: 17464088
[TBL] [Abstract][Full Text] [Related]
4. Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts.
Copaja M; Venegas D; Aránguiz P; Canales J; Vivar R; Catalán M; Olmedo I; Rodríguez AE; Chiong M; Leyton L; Lavandero S; Díaz-Araya G
Toxicol Appl Pharmacol; 2011 Aug; 255(1):57-64. PubMed ID: 21651924
[TBL] [Abstract][Full Text] [Related]
5. Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway.
Song JX; Ren JY; Chen H
J Cardiovasc Pharmacol; 2011 Feb; 57(2):213-22. PubMed ID: 21052011
[TBL] [Abstract][Full Text] [Related]
6. Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms.
Turner NA; Aley PK; Hall KT; Warburton P; Galloway S; Midgley L; O'Regan DJ; Wood IC; Ball SG; Porter KE
J Mol Cell Cardiol; 2007 Aug; 43(2):168-76. PubMed ID: 17560598
[TBL] [Abstract][Full Text] [Related]
7. Role of RhoA inactivation in reduced cell proliferation of human airway smooth muscle by simvastatin.
Takeda N; Kondo M; Ito S; Ito Y; Shimokata K; Kume H
Am J Respir Cell Mol Biol; 2006 Dec; 35(6):722-9. PubMed ID: 16858009
[TBL] [Abstract][Full Text] [Related]
8. Simvastatin potentiates tumor necrosis factor alpha-mediated apoptosis of human vascular endothelial cells via the inhibition of the geranylgeranylation of RhoA.
Tang D; Park HJ; Georgescu SP; Sebti SM; Hamilton AD; Galper JB
Life Sci; 2006 Sep; 79(15):1484-92. PubMed ID: 16740276
[TBL] [Abstract][Full Text] [Related]
9. HMG-CoA reductase inhibitor simvastatin overcomes bortezomib-induced apoptosis resistance by disrupting a geranylgeranyl pyrophosphate-dependent survival pathway.
Fuchs D; Berges C; Opelz G; Daniel V; Naujokat C
Biochem Biophys Res Commun; 2008 Sep; 374(2):309-14. PubMed ID: 18625202
[TBL] [Abstract][Full Text] [Related]
10. Decreased C-reactive protein-induced resistin production in human monocytes by simvastatin.
Hu WL; Qiao SB; Li JJ
Cytokine; 2007 Dec; 40(3):201-6. PubMed ID: 18023360
[TBL] [Abstract][Full Text] [Related]
11. Simvastatin inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levels.
Turner NA; O'Regan DJ; Ball SG; Porter KE
FASEB J; 2005 May; 19(7):804-6. PubMed ID: 15728660
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of RhoA/Rho-kinase pathway suppresses the expression of type I collagen induced by TGF-beta2 in human retinal pigment epithelial cells.
Itoh Y; Kimoto K; Imaizumi M; Nakatsuka K
Exp Eye Res; 2007 Mar; 84(3):464-72. PubMed ID: 17217948
[TBL] [Abstract][Full Text] [Related]
13. HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.
Al-Haidari AA; Syk I; Thorlacius H
Biochem Biophys Res Commun; 2014 Mar; 446(1):68-72. PubMed ID: 24582560
[TBL] [Abstract][Full Text] [Related]
14. Statins suppress THP-1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranylgeranylation.
Wong B; Lumma WC; Smith AM; Sisko JT; Wright SD; Cai TQ
J Leukoc Biol; 2001 Jun; 69(6):959-62. PubMed ID: 11404382
[TBL] [Abstract][Full Text] [Related]
15. Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells.
Ogunwobi OO; Beales IL
Am J Gastroenterol; 2008 Apr; 103(4):825-37. PubMed ID: 18371146
[TBL] [Abstract][Full Text] [Related]
16. Simvastatin inhibits production of interleukin 6 (IL-6) and IL-8 and cell proliferation induced by tumor necrosis factor-alpha in fibroblast-like synoviocytes from patients with rheumatoid arthritis.
Yokota K; Miyazaki T; Hirano M; Akiyama Y; Mimura T
J Rheumatol; 2006 Mar; 33(3):463-71. PubMed ID: 16511915
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of the RhoA/Rho-associated, coiled-coil-containing protein kinase-1 pathway is involved in the therapeutic effects of simvastatin on pulmonary arterial hypertension.
Liu WH; Xu XH; Luo Q; Zhang HL; Wang Y; Xi QY; Zhao ZH; Liu ZH
Clin Exp Hypertens; 2018; 40(3):224-230. PubMed ID: 29319354
[TBL] [Abstract][Full Text] [Related]
18. Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway.
Yamashita M; Otsuka F; Mukai T; Otani H; Inagaki K; Miyoshi T; Goto J; Yamamura M; Makino H
J Endocrinol; 2008 Mar; 196(3):601-13. PubMed ID: 18310456
[TBL] [Abstract][Full Text] [Related]
19. Statins suppress MMP2 secretion via inactivation of RhoA/ROCK pathway in pulmonary vascular smooth muscles cells.
Li M; Li Z; Sun X
Eur J Pharmacol; 2008 Sep; 591(1-3):219-23. PubMed ID: 18619957
[TBL] [Abstract][Full Text] [Related]
20. HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1.
Morikawa-Futamatsu K; Adachi S; Maejima Y; Tamamori-Adachi M; Suzuki J; Kitajima S; Ito H; Isobe M
Life Sci; 2006 Aug; 79(14):1380-90. PubMed ID: 16712874
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
