165 related articles for article (PubMed ID: 14985094)
1. Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase.
Sienaert R; Andrei G; Snoeck R; De Clercq E; McGuigan C; Balzarini J
Biochem Biophys Res Commun; 2004 Mar; 315(4):877-83. PubMed ID: 14985094
[TBL] [Abstract][Full Text] [Related]
2. Bicyclic pyrimidine nucleoside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication.
Balzarini J; McGuigan C
J Antimicrob Chemother; 2002 Jul; 50(1):5-9. PubMed ID: 12096000
[TBL] [Abstract][Full Text] [Related]
3. Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides.
Balzarini J; McGuigan C
Biochim Biophys Acta; 2002 Jul; 1587(2-3):287-95. PubMed ID: 12084470
[TBL] [Abstract][Full Text] [Related]
4. Specific recognition of the bicyclic pyrimidine nucleoside analogs, a new class of highly potent and selective inhibitors of varicella-zoster virus (VZV), by the VZV-encoded thymidine kinase.
Sienaert R; Naesens L; Brancale A; De Clercq E; McGuigan C; Balzarini J
Mol Pharmacol; 2002 Feb; 61(2):249-54. PubMed ID: 11809847
[TBL] [Abstract][Full Text] [Related]
5. Bicyclic nucleoside inhibitors of varicella-zoster virus modified on the sugar moiety: 3' and 5' derivatives.
Luoni GM; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Antivir Chem Chemother; 2004 Nov; 15(6):333-41. PubMed ID: 15646647
[TBL] [Abstract][Full Text] [Related]
6. 2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743.
McGuigan C; Derudas M; Quintiliani M; Andrei G; Snoeck R; Henson G; Balzarini J
Bioorg Med Chem Lett; 2009 Nov; 19(22):6264-7. PubMed ID: 19833513
[TBL] [Abstract][Full Text] [Related]
7. Identification and analysis of the simian varicella virus thymidine kinase gene.
Pumphrey CY; Gray WL
Arch Virol; 1996; 141(1):43-55. PubMed ID: 8629950
[TBL] [Abstract][Full Text] [Related]
8. Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d]pyrimidine nucleoside analogues.
De Clercq E
Med Res Rev; 2003 May; 23(3):253-74. PubMed ID: 12647310
[TBL] [Abstract][Full Text] [Related]
9. In vitro-selected drug-resistant varicella-zoster virus mutants in the thymidine kinase and DNA polymerase genes yield novel phenotype-genotype associations and highlight differences between antiherpesvirus drugs.
Andrei G; Topalis D; Fiten P; McGuigan C; Balzarini J; Opdenakker G; Snoeck R
J Virol; 2012 Mar; 86(5):2641-52. PubMed ID: 22190713
[TBL] [Abstract][Full Text] [Related]
10. Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus.
McGuigan C; Pathirana RN; Migliore M; Adak R; Luoni G; Jones AT; Díez-Torrubia A; Camarasa MJ; Velázquez S; Henson G; Verbeken E; Sienaert R; Naesens L; Snoeck R; Andrei G; Balzarini J
J Antimicrob Chemother; 2007 Dec; 60(6):1316-30. PubMed ID: 17956908
[TBL] [Abstract][Full Text] [Related]
11. Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer.
Degrève B; Andrei G; Izquierdo M; Piette J; Morin K; Knaus EE; Wiebe LI; Basrah I; Walker RT; De Clercq E; Balzarini J
Gene Ther; 1997 Oct; 4(10):1107-14. PubMed ID: 9415318
[TBL] [Abstract][Full Text] [Related]
12. Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides.
Andrei G; Sienaert R; McGuigan C; De Clercq E; Balzarini J; Snoeck R
Antimicrob Agents Chemother; 2005 Mar; 49(3):1081-6. PubMed ID: 15728906
[TBL] [Abstract][Full Text] [Related]
13. Mutations distal to the substrate site can affect varicella zoster virus thymidine kinase activity: implications for drug design.
El Omari K; Liekens S; Bird LE; Balzarini J; Stammers DK
Mol Pharmacol; 2006 Jun; 69(6):1891-6. PubMed ID: 16556772
[TBL] [Abstract][Full Text] [Related]
14. Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase.
Balzarini J; Sienaert R; Liekens S; Van Kuilenburg A; Carangio A; Esnouf R; De Clercq E; McGuigan C
Mol Pharmacol; 2002 May; 61(5):1140-5. PubMed ID: 11961132
[TBL] [Abstract][Full Text] [Related]
15. The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase.
Balzarini J; Liekens S; Esnouf R; De Clercq E
Biochemistry; 2002 May; 41(20):6517-24. PubMed ID: 12009916
[TBL] [Abstract][Full Text] [Related]
16. A p-[18F]fluoroethoxyphenyl bicyclic nucleoside analogue as a potential positron emission tomography imaging agent for varicella-zoster virus thymidine kinase gene expression.
Chitneni SK; Deroose CM; Balzarini J; Gijsbers R; Celen S; Debyser Z; Mortelmans L; Verbruggen AM; Bormans GM
J Med Chem; 2007 Dec; 50(26):6627-37. PubMed ID: 18047266
[TBL] [Abstract][Full Text] [Related]
17. Metabolic and pharmacological characteristics of the bicyclic nucleoside analogues (BCNAs) as highly selective inhibitors of varicella-zoster virus (VZV).
Sienaert R; Naesens L; Brancale A; Carangio A; Andrei G; Snoeck R; Van Kuilenburg A; De Clercq E; McGuigan C; Balzarini J
Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):995-7. PubMed ID: 14565329
[No Abstract] [Full Text] [Related]
18. Structure-activity relationship of the affinity of 5-substituted uracil nucleoside analogues for varicella-zoster virus thymidine kinase and their activity against varicella-zoster virus.
Ashida N; Watanabe Y; Miura S; Kano F; Sakata S; Yamaguchi T; Suzutani T; Machida H
Antiviral Res; 1997 Aug; 35(3):167-75. PubMed ID: 9298756
[TBL] [Abstract][Full Text] [Related]
19. Bicyclic nucleoside inhibitors of varicella-zoster virus: 5'-chloro and 3'-chloro derivatives.
Luoni G; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):931-3. PubMed ID: 14565314
[TBL] [Abstract][Full Text] [Related]
20. Sequence analysis of the leftward end of simian varicella virus (EcoRI-I fragment) reveals the presence of an 8-bp repeat flanking the unique long segment and an 881-bp open-reading frame that is absent in the varicella zoster virus genome.
Mahalingam R; White T; Wellish M; Gilden DH; Soike K; Gray WL
Virology; 2000 Sep; 274(2):420-8. PubMed ID: 10964784
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
