113 related articles for article (PubMed ID: 14985108)
1. Glycosylation of onconase increases its conformational stability and toxicity for cancer cells.
Kim BM; Kim H; Raines RT; Lee Y
Biochem Biophys Res Commun; 2004 Mar; 315(4):976-83. PubMed ID: 14985108
[TBL] [Abstract][Full Text] [Related]
2. Contribution of active-site residues to the function of onconase, a ribonuclease with antitumoral activity.
Lee JE; Raines RT
Biochemistry; 2003 Oct; 42(39):11443-50. PubMed ID: 14516195
[TBL] [Abstract][Full Text] [Related]
3. Endowing human pancreatic ribonuclease with toxicity for cancer cells.
Leland PA; Staniszewski KE; Kim BM; Raines RT
J Biol Chem; 2001 Nov; 276(46):43095-102. PubMed ID: 11555655
[TBL] [Abstract][Full Text] [Related]
4. Linker length affects expression and bioactivity of the onconase fusion protein in Pichia pastoris.
Yang GG; Xu XY; Ding Y; Cui QQ; Wang Z; Zhang QY; Shi SH; Lv ZY; Wang XY; Zhang JH; Zhang RG; Xu CS
Genet Mol Res; 2015 Dec; 14(4):19360-70. PubMed ID: 26782589
[TBL] [Abstract][Full Text] [Related]
5. The interdependence between catalytic activity, conformational stability, and cytotoxicity of onconase.
Schulenburg C; Ardelt B; Ardelt W; Arnold U; Shogen K; Ulbrich-Hofmann R; Darzynkiewicz Z
Cancer Biol Ther; 2007 Aug; 6(8):1233-9. PubMed ID: 17637563
[TBL] [Abstract][Full Text] [Related]
6. Constitutive expression and anticancer potency of a novel immunotoxin onconase-DV3.
Sun M; Tang H; Gao Y; Dai X; Yuan Y; Zhang C; Sun D
Oncol Rep; 2016 Apr; 35(4):1987-94. PubMed ID: 26782924
[TBL] [Abstract][Full Text] [Related]
7. Onconase dimerization through 3D domain swapping: structural investigations and increase in the apoptotic effect in cancer cells.
Fagagnini A; Pica A; Fasoli S; Montioli R; Donadelli M; Cordani M; Butturini E; Acquasaliente L; Picone D; Gotte G
Biochem J; 2017 Nov; 474(22):3767-3781. PubMed ID: 28963346
[TBL] [Abstract][Full Text] [Related]
8. KFERQ sequence in ribonuclease A-mediated cytotoxicity.
Haigis MC; Kurten EL; Abel RL; Raines RT
J Biol Chem; 2002 Mar; 277(13):11576-81. PubMed ID: 11801605
[TBL] [Abstract][Full Text] [Related]
9. Contribution of structural peculiarities of onconase to its high stability and folding kinetics.
Arnold U; Schulenburg C; Schmidt D; Ulbrich-Hofmann R
Biochemistry; 2006 Mar; 45(11):3580-7. PubMed ID: 16533040
[TBL] [Abstract][Full Text] [Related]
10. Contribution of chain termini to the conformational stability and biological activity of onconase.
Notomista E; Catanzano F; Graziano G; Di Gaetano S; Barone G; Di Donato A
Biochemistry; 2001 Aug; 40(31):9097-103. PubMed ID: 11478876
[TBL] [Abstract][Full Text] [Related]
11. Structural basis for catalysis by onconase.
Lee JE; Bae E; Bingman CA; Phillips GN; Raines RT
J Mol Biol; 2008 Jan; 375(1):165-77. PubMed ID: 18001769
[TBL] [Abstract][Full Text] [Related]
12. The role of N-glycosylation sites in the activity, stability, and expression of the recombinant elastase expressed by Pichia pastoris.
Han M; Wang X; Ding H; Jin M; Yu L; Wang J; Yu X
Enzyme Microb Technol; 2014 Jan; 54():32-7. PubMed ID: 24267565
[TBL] [Abstract][Full Text] [Related]
13. Role of the N terminus in RNase A homologues: differences in catalytic activity, ribonuclease inhibitor interaction and cytotoxicity.
Boix E; Wu Y; Vasandani VM; Saxena SK; Ardelt W; Ladner J; Youle RJ
J Mol Biol; 1996 Apr; 257(5):992-1007. PubMed ID: 8632481
[TBL] [Abstract][Full Text] [Related]
14. Expression of soluble bovine pancreatic ribonuclease A in Pichia pastoris and its purification and characterization.
Chatani E; Tanimizu N; Ueno H; Hayashi R
Biosci Biotechnol Biochem; 2000 Nov; 64(11):2437-44. PubMed ID: 11193413
[TBL] [Abstract][Full Text] [Related]
15. A synapomorphic disulfide bond is critical for the conformational stability and cytotoxicity of an amphibian ribonuclease.
Leland PA; Staniszewski KE; Kim B; Raines RT
FEBS Lett; 2000 Jul; 477(3):203-7. PubMed ID: 10908721
[TBL] [Abstract][Full Text] [Related]
16. Conformational stability is a determinant of ribonuclease A cytotoxicity.
Klink TA; Raines RT
J Biol Chem; 2000 Jun; 275(23):17463-7. PubMed ID: 10747991
[TBL] [Abstract][Full Text] [Related]
17. A ribonuclease A variant with low catalytic activity but high cytotoxicity.
Bretscher LE; Abel RL; Raines RT
J Biol Chem; 2000 Apr; 275(14):9893-6. PubMed ID: 10744660
[TBL] [Abstract][Full Text] [Related]
18. Onconase: an unusually stable protein.
Notomista E; Catanzano F; Graziano G; Dal Piaz F; Barone G; D'Alessio G; Di Donato A
Biochemistry; 2000 Aug; 39(30):8711-8. PubMed ID: 10913282
[TBL] [Abstract][Full Text] [Related]
19. Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity.
Rutkoski TJ; Raines RT
Curr Pharm Biotechnol; 2008 Jun; 9(3):185-9. PubMed ID: 18673284
[TBL] [Abstract][Full Text] [Related]
20. The importance of dynamic effects on the enzyme activity: X-ray structure and molecular dynamics of onconase mutants.
Merlino A; Mazzarella L; Carannante A; Di Fiore A; Di Donato A; Notomista E; Sica F
J Biol Chem; 2005 May; 280(18):17953-60. PubMed ID: 15728177
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]