128 related articles for article (PubMed ID: 14985458)
1. R115777 induces Ras-independent apoptosis of myeloma cells via multiple intrinsic pathways.
Beaupre DM; Cepero E; Obeng EA; Boise LH; Lichtenheld MG
Mol Cancer Ther; 2004 Feb; 3(2):179-86. PubMed ID: 14985458
[TBL] [Abstract][Full Text] [Related]
2. Farnesyl transferase inhibitors enhance death receptor signals and induce apoptosis in multiple myeloma cells.
Beaupre DM; McCafferty-Grad J; Bahlis NJ; Boise LH; Lichtenheld MG
Leuk Lymphoma; 2003 Dec; 44(12):2123-34. PubMed ID: 14959858
[TBL] [Abstract][Full Text] [Related]
3. Characterization of a R115777-resistant human multiple myeloma cell line with cross-resistance to PS-341.
Buzzeo R; Enkemann S; Nimmanapalli R; Alsina M; Lichtenheld MG; Dalton WS; Beaupre DM
Clin Cancer Res; 2005 Aug; 11(16):6057-64. PubMed ID: 16115951
[TBL] [Abstract][Full Text] [Related]
4. Farnesyl transferase inhibitor R115777 induces apoptosis of human myeloma cells.
Le Gouill S; Pellat-Deceunynck C; Harousseau JL; Rapp MJ; Robillard N; Bataille R; Amiot M
Leukemia; 2002 Sep; 16(9):1664-7. PubMed ID: 12200678
[TBL] [Abstract][Full Text] [Related]
5. The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.
Zhang XD; Gillespie SK; Borrow JM; Hersey P
Mol Cancer Ther; 2004 Apr; 3(4):425-35. PubMed ID: 15078986
[TBL] [Abstract][Full Text] [Related]
6. The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways.
Caraglia M; Marra M; Viscomi C; D'Alessandro AM; Budillon A; Meo G; Arra C; Barbieri A; Rapp UR; Baldi A; Tassone P; Venuta S; Abbruzzese A; Tagliaferri P
Int J Cancer; 2007 Nov; 121(10):2317-30. PubMed ID: 17657738
[TBL] [Abstract][Full Text] [Related]
7. R115777 (Zarnestra)/Zoledronic acid (Zometa) cooperation on inhibition of prostate cancer proliferation is paralleled by Erk/Akt inactivation and reduced Bcl-2 and bad phosphorylation.
Caraglia M; Marra M; Leonetti C; Meo G; D'Alessandro AM; Baldi A; Santini D; Tonini G; Bertieri R; Zupi G; Budillon A; Abbruzzese A
J Cell Physiol; 2007 May; 211(2):533-43. PubMed ID: 17192846
[TBL] [Abstract][Full Text] [Related]
8. Effect of farnesyl transferase inhibitor R115777 on the growth of fresh and cloned myeloma cells in vitro.
Ochiai N; Uchida R; Fuchida S; Okano A; Okamoto M; Ashihara E; Inaba T; Fujita N; Matsubara H; Shimazaki C
Blood; 2003 Nov; 102(9):3349-53. PubMed ID: 12842991
[TBL] [Abstract][Full Text] [Related]
9. The small-molecule Bcl-2 inhibitor HA14-1 interacts synergistically with flavopiridol to induce mitochondrial injury and apoptosis in human myeloma cells through a free radical-dependent and Jun NH2-terminal kinase-dependent mechanism.
Pei XY; Dai Y; Grant S
Mol Cancer Ther; 2004 Dec; 3(12):1513-24. PubMed ID: 15634644
[TBL] [Abstract][Full Text] [Related]
10. Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin's lymphoma and multiple myeloma cell lines to paclitaxel-induced apoptosis.
Jazirehi AR; Bonavida B
Mol Cancer Ther; 2004 Jan; 3(1):71-84. PubMed ID: 14749477
[TBL] [Abstract][Full Text] [Related]
11. Combining prenylation inhibitors causes synergistic cytotoxicity, apoptosis and disruption of RAS-to-MAP kinase signalling in multiple myeloma cells.
Morgan MA; Sebil T; Aydilek E; Peest D; Ganser A; Reuter CW
Br J Haematol; 2005 Sep; 130(6):912-25. PubMed ID: 16156861
[TBL] [Abstract][Full Text] [Related]
12. Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax.
Panaretakis T; Pokrovskaja K; Shoshan MC; Grandér D
Oncogene; 2003 Jul; 22(29):4543-56. PubMed ID: 12881711
[TBL] [Abstract][Full Text] [Related]
13. Farnesyltransferase inhibitor BMS-214662 induces apoptosis in myeloma cells through PUMA up-regulation, Bax and Bak activation, and Mcl-1 elimination.
Gómez-Benito M; Marzo I; Anel A; Naval J
Mol Pharmacol; 2005 Jun; 67(6):1991-8. PubMed ID: 15738311
[TBL] [Abstract][Full Text] [Related]
14. Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction.
Seo SK; Lee HC; Woo SH; Jin HO; Yoo DH; Lee SJ; An S; Choe TB; Park MJ; Hong SI; Park IC; Rhee CH
Apoptosis; 2007 Jan; 12(1):195-209. PubMed ID: 17136320
[TBL] [Abstract][Full Text] [Related]
15. Green tea component, catechin, induces apoptosis of human malignant B cells via production of reactive oxygen species.
Nakazato T; Ito K; Ikeda Y; Kizaki M
Clin Cancer Res; 2005 Aug; 11(16):6040-9. PubMed ID: 16115949
[TBL] [Abstract][Full Text] [Related]
16. Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cells.
Marzo I; Pérez-Galán P; Giraldo P; López-Royuela N; Gómez-Benito M; Larrad L; Lasierra P; Rubio-Félix D; Anel A; Naval J
Leukemia; 2004 Oct; 18(10):1599-604. PubMed ID: 15356656
[TBL] [Abstract][Full Text] [Related]
17. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
Wu SJ; Ng LT; Lin CC
Eur J Pharmacol; 2005 Aug; 518(2-3):96-106. PubMed ID: 16054126
[TBL] [Abstract][Full Text] [Related]
18. Arsenic trioxide induces apoptosis in pancreatic cancer cells via changes in cell cycle, caspase activation, and GADD expression.
Li X; Ding X; Adrian TE
Pancreas; 2003 Aug; 27(2):174-9. PubMed ID: 12883267
[TBL] [Abstract][Full Text] [Related]
19. Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation.
Rosato RR; Dai Y; Almenara JA; Maggio SC; Grant S
Leukemia; 2004 Nov; 18(11):1780-8. PubMed ID: 15385934
[TBL] [Abstract][Full Text] [Related]
20. Silencing of JMJD2B induces cell apoptosis via mitochondria-mediated and death receptor-mediated pathway activation in colorectal cancer.
Sun BB; Fu LN; Wang YQ; Gao QY; Xu J; Cao ZJ; Chen YX; Fang JY
J Dig Dis; 2014 Sep; 15(9):491-500. PubMed ID: 24957706
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]