BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

305 related articles for article (PubMed ID: 14987060)

  • 1. Biochemical characterization of the SgcA1 alpha-D-glucopyranosyl-1-phosphate thymidylyltransferase from the enediyne antitumor antibiotic C-1027 biosynthetic pathway and overexpression of sgcA1 in Streptomyces globisporus to improve C-1027 production.
    Murrell JM; Liu W; Shen B
    J Nat Prod; 2004 Feb; 67(2):206-13. PubMed ID: 14987060
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biosynthesis of the enediyne antitumor antibiotic C-1027.
    Liu W; Christenson SD; Standage S; Shen B
    Science; 2002 Aug; 297(5584):1170-3. PubMed ID: 12183628
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cloning and expression of glucose-1-phosphate thymidylyltransferase gene (schS6) from Streptomyces sp. SCC-2136.
    Han JM; Kim SM; Lee HJ; Yoo JC
    J Microbiol Biotechnol; 2007 Apr; 17(4):685-90. PubMed ID: 18051285
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disruption of cagA, the apoprotein gene of chromoprotein antibiotic C-1027, eliminates holo-antibiotic production, but not the cytotoxic chromophore.
    Cui Z; Wang L; Wang S; Li G; Hong B
    FEMS Microbiol Lett; 2009 Nov; 301(1):57-68. PubMed ID: 19845765
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of alpha-D-glucose-1-phosphate cytidylyltransferase involved in Ebosin biosynthesis of Streptomyces sp. 139.
    Qi XQ; Sun QL; Bai LP; Shan JJ; Zhang Y; Zhang R; Li Y
    Appl Microbiol Biotechnol; 2009 May; 83(2):361-8. PubMed ID: 19330326
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Nucleotide sequence analysis of an antibiotic biosynthesis gene of Streptomyces globisporus].
    Mao X; Li Y
    Wei Sheng Wu Xue Bao; 1998 Feb; 38(1):32-6. PubMed ID: 12549386
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
    Barton WA; Lesniak J; Biggins JB; Jeffrey PD; Jiang J; Rajashankar KR; Thorson JS; Nikolov DB
    Nat Struct Biol; 2001 Jun; 8(6):545-51. PubMed ID: 11373625
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Precursor for biosynthesis of sugar moiety of doxorubicin depends on rhamnose biosynthetic pathway in Streptomyces peucetius ATCC 27952.
    Singh B; Lee CB; Sohng JK
    Appl Microbiol Biotechnol; 2010 Feb; 85(5):1565-74. PubMed ID: 19777229
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of biosynthetic gene cluster for the production of virginiamycin M, a streptogramin type A antibiotic, in Streptomyces virginiae.
    Pulsawat N; Kitani S; Nihira T
    Gene; 2007 May; 393(1-2):31-42. PubMed ID: 17350183
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Complete genome sequence of Streptomyces globisporus C-1027, the producer of an enediyne antibiotic lidamycin.
    Li X; Lei X; Zhang C; Jiang Z; Shi Y; Wang S; Wang L; Hong B
    J Biotechnol; 2016 Mar; 222():9-10. PubMed ID: 26853480
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetic and crystallographic analyses support a sequential-ordered bi bi catalytic mechanism for Escherichia coli glucose-1-phosphate thymidylyltransferase.
    Zuccotti S; Zanardi D; Rosano C; Sturla L; Tonetti M; Bolognesi M
    J Mol Biol; 2001 Nov; 313(4):831-43. PubMed ID: 11697907
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cloning and characterization of CalS7 from Micromonospora echinospora sp. calichensis as a glucose-1-phosphate nucleotidyltransferase.
    Simkhada D; Oh TJ; Kim EM; Yoo JC; Sohng JK
    Biotechnol Lett; 2009 Jan; 31(1):147-53. PubMed ID: 18807197
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis.
    Christenson SD; Liu W; Toney MD; Shen B
    J Am Chem Soc; 2003 May; 125(20):6062-3. PubMed ID: 12785829
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Purification and primary structure of C-1027-AG, a selective antagonist of antitumor antibiotic C-1027, from Streptomyces globisporus.
    Otani T; Yasuhara T; Minami Y; Shimazu T; Zhang R; Xie MY
    Agric Biol Chem; 1991 Feb; 55(2):407-17. PubMed ID: 1368692
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein.
    Liu W; Shen B
    Antimicrob Agents Chemother; 2000 Feb; 44(2):382-92. PubMed ID: 10639366
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional characterization of ketoreductase (rubN6) and aminotransferase (rubN4) genes in the gene cluster of Streptomyces achromogenes var. rubradiris.
    Lamichhane J; Liou K; Lee HC; Kim CG; Sohng JK
    Biotechnol Lett; 2006 Apr; 28(8):545-53. PubMed ID: 16614891
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.
    Thuy TT; Liou K; Oh TJ; Kim DH; Nam DH; Yoo JC; Sohng JK
    Glycobiology; 2007 Feb; 17(2):119-26. PubMed ID: 17053005
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564.
    Mao Y; Varoglu M; Sherman DH
    Chem Biol; 1999 Apr; 6(4):251-63. PubMed ID: 10099135
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Draft genome sequence of Streptomyces globisporus C-1027, which produces an antitumor antibiotic consisting of a nine-membered enediyne with a chromoprotein.
    Wang L; Wang S; He Q; Yu T; Li Q; Hong B
    J Bacteriol; 2012 Aug; 194(15):4144. PubMed ID: 22815456
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Improvement of the enediyne antitumor antibiotic C-1027 production by manipulating its biosynthetic pathway regulation in Streptomyces globisporus.
    Chen Y; Yin M; Horsman GP; Shen B
    J Nat Prod; 2011 Mar; 74(3):420-4. PubMed ID: 21250756
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.