BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

86 related articles for article (PubMed ID: 1499092)

  • 1. Mutagenesis by (+)-anti-B[a]P-N2-Gua, the major adduct of activated benzo[a]pyrene, when studied in an Escherichia coli plasmid using site-directed methods.
    Mackay W; Benasutti M; Drouin E; Loechler EL
    Carcinogenesis; 1992 Aug; 13(8):1415-25. PubMed ID: 1499092
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A role for DNA polymerase V in G --> T mutations from the major benzo[a]pyrene N2-dG adduct when studied in a 5'-TGT sequence in E. coli.
    Yin J; Seo KY; Loechler EL
    DNA Repair (Amst); 2004 Mar; 3(3):323-34. PubMed ID: 15177047
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutational specificity of the (+)-anti-diol epoxide of benzo[a]pyrene in a supF gene of an Escherichia coli plasmid: DNA sequence context influences hotspots, mutagenic specificity and the extent of SOS enhancement of mutagenesis.
    Rodriguez H; Loechler EL
    Carcinogenesis; 1993 Mar; 14(3):373-83. PubMed ID: 8453713
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The major, N2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide is capable of inducing G-->A and G-->C, in addition to G-->T, mutations.
    Jelinsky SA; Liu T; Geacintov NE; Loechler EL
    Biochemistry; 1995 Oct; 34(41):13545-53. PubMed ID: 7577943
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sequence specific mutagenesis of the major (+)-anti-benzo[a]pyrene diol epoxide-DNA adduct at a mutational hot spot in vitro and in Escherichia coli cells.
    Hanrahan CJ; Bacolod MD; Vyas RR; Liu T; Geacintov NE; Loechler EL; Basu AK
    Chem Res Toxicol; 1997 Apr; 10(4):369-77. PubMed ID: 9114972
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Construction of an Escherichia coli vector containing the major DNA adduct of activated benzo[a]pyrene at a defined site.
    Benasutti M; Ezzedine ZD; Loechler EL
    Chem Res Toxicol; 1988; 1(3):160-8. PubMed ID: 2979726
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeted A --> T and G --> T mutations induced by site-specific deoxyadenosine and deoxyguanosine adducts, respectively, from the (+)-anti-diol epoxide of dibenz[a,j]anthracene in M13mp7L2.
    Min Z; Gill RD; Cortez C; Harvey RG; Loechler EL; DiGiovanni J
    Biochemistry; 1996 Apr; 35(13):4128-38. PubMed ID: 8672448
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutagenesis by the (+)-anti-diol epoxide of benzo[a]pyrene: what controls mutagenic specificity?
    Rodriguez H; Loechler EL
    Biochemistry; 1993 Feb; 32(7):1759-69. PubMed ID: 8439538
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutagenesis studies with four stereoisomeric N2-dG benzo[a]pyrene adducts in the identical 5'-CGC sequence used in NMR studies: G->T mutations dominate in each case.
    Seo KY; Nagalingam A; Tiffany M; Loechler EL
    Mutagenesis; 2005 Nov; 20(6):441-8. PubMed ID: 16311255
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The major, N2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide can be unstable in double-stranded DNA.
    Drouin EE; Lech J; Loechler EL
    Biochemistry; 1995 Feb; 34(7):2251-9. PubMed ID: 7857936
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutagenic potential of stereoisomeric bay region (+)- and (-)-cis-anti-benzo[a]pyrene diol epoxide-N2-2'-deoxyguanosine adducts in Escherichia coli and simian kidney cells.
    Fernandes A; Liu T; Amin S; Geacintov NE; Grollman AP; Moriya M
    Biochemistry; 1998 Jul; 37(28):10164-72. PubMed ID: 9665722
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The major, N2-dG adduct of (+)-anti-B[a]PDE induces G-->A mutations in a 5'-AGA-3' sequence context.
    Shukla R; Geacintov NE; Loechler EL
    Carcinogenesis; 1999 Feb; 20(2):261-8. PubMed ID: 10069463
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutational properties of the primary aflatoxin B1-DNA adduct.
    Bailey EA; Iyer RS; Stone MP; Harris TM; Essigmann JM
    Proc Natl Acad Sci U S A; 1996 Feb; 93(4):1535-9. PubMed ID: 8643667
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The major, N2-dG adduct of (+)-anti-B[a]PDE shows a dramatically different mutagenic specificity (predominantly, G --> A) in a 5'-CGT-3' sequence context.
    Shukla R; Liu T; Geacintov NE; Loechler EL
    Biochemistry; 1997 Aug; 36(33):10256-61. PubMed ID: 9254624
    [TBL] [Abstract][Full Text] [Related]  

  • 15. How stereochemistry affects mutagenesis by N2-deoxyguanosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene: configuration of the adduct bond is more important than those of the hydroxyl groups.
    Shukla R; Jelinsky S; Liu T; Geacintov NE; Loechler EL
    Biochemistry; 1997 Oct; 36(43):13263-9. PubMed ID: 9341216
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Are base substitution and frameshift mutagenesis pathways interrelated? An analysis based upon studies of the frequencies and specificities of mutations induced by the (+)-anti diol epoxide of benzo[a]pyrene.
    Rodriguez H; Loechler EL
    Mutat Res; 1995 Jan; 326(1):29-37. PubMed ID: 7528883
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mirror image stereoisomers of the major benzo[a]pyrene N2-dG adduct are bypassed by different lesion-bypass DNA polymerases in E. coli.
    Seo KY; Nagalingam A; Miri S; Yin J; Chandani S; Kolbanovskiy A; Shastry A; Loechler EL
    DNA Repair (Amst); 2006 Apr; 5(4):515-22. PubMed ID: 16483853
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Misincorporation of nucleotides opposite five-membered exocyclic ring guanine derivatives by escherichia coli polymerases in vitro and in vivo: 1,N2-ethenoguanine, 5,6,7,9-tetrahydro-9-oxoimidazo[1, 2-a]purine, and 5,6,7,9-tetrahydro-7-hydroxy-9-oxoimidazo[1, 2-a]purine.
    Langouët S; Mican AN; Müller M; Fink SP; Marnett LJ; Muhle SA; Guengerich FP
    Biochemistry; 1998 Apr; 37(15):5184-93. PubMed ID: 9548749
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutagenesis studies of the major benzo[a]pyrene N2-dG adduct in a 5'-TG versus a 5'-UG sequence: removal of the methyl group causes a modest decrease in the [G->T/G->A] mutational ratio.
    Nagalingam A; Seo KY; Loechler EL
    Mutagenesis; 2005 Mar; 20(2):105-10. PubMed ID: 15755802
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative mutagenesis of the C8-guanine adducts of 1-nitropyrene and 1,6- and 1,8-dinitropyrene in a CpG repeat sequence. A slipped frameshift intermediate model for dinucleotide deletion.
    Hilario P; Yan S; Hingerty BE; Broyde S; Basu AK
    J Biol Chem; 2002 Nov; 277(47):45068-74. PubMed ID: 12239219
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.