BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 14990989)

  • 21. Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells.
    Orimoto K; Tsuchiya H; Kobayashi T; Matsuda T; Hino O
    Biochem Biophys Res Commun; 1996 Feb; 219(1):70-5. PubMed ID: 8619830
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Distinct effects of single amino-acid changes to tuberin on the function of the tuberin-hamartin complex.
    Nellist M; Sancak O; Goedbloed MA; Rohe C; van Netten D; Mayer K; Tucker-Williams A; van den Ouweland AM; Halley DJ
    Eur J Hum Genet; 2005 Jan; 13(1):59-68. PubMed ID: 15483652
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Morphoproteomic and molecular concomitants of an overexpressed and activated mTOR pathway in renal cell carcinomas.
    Lin F; Zhang PL; Yang XJ; Prichard JW; Lun M; Brown RE
    Ann Clin Lab Sci; 2006; 36(3):283-93. PubMed ID: 16951269
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Renal tumour suppressor function of the Birt-Hogg-Dubé syndrome gene product folliculin.
    Hudon V; Sabourin S; Dydensborg AB; Kottis V; Ghazi A; Paquet M; Crosby K; Pomerleau V; Uetani N; Pause A
    J Med Genet; 2010 Mar; 47(3):182-9. PubMed ID: 19843504
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Absence of allelic loss in cytomegalic neurons of cortical tuber in the Eker rat model of tuberous sclerosis.
    Mizuguchi M; Mori M; Nozaki Y; Momoi MY; Itoh M; Takashima S; Hino O
    Acta Neuropathol; 2004 Jan; 107(1):47-52. PubMed ID: 14566415
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer.
    Ma L; Teruya-Feldstein J; Bonner P; Bernardi R; Franz DN; Witte D; Cordon-Cardo C; Pandolfi PP
    Cancer Res; 2007 Aug; 67(15):7106-12. PubMed ID: 17671177
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Isolation and characterization of a rat homologue of the human tuberous sclerosis 1 gene (Tsc1) and analysis of its mutations in rat renal carcinomas.
    Satake N; Kobayashi T; Kobayashi E; Izumi K; Hino O
    Cancer Res; 1999 Feb; 59(4):849-55. PubMed ID: 10029074
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Constant allelic alteration on chromosome 16p (TSC2 gene) in perivascular epithelioid cell tumour (PEComa): genetic evidence for the relationship of PEComa with angiomyolipoma.
    Pan CC; Chung MY; Ng KF; Liu CY; Wang JS; Chai CY; Huang SH; Chen PC; Ho DM
    J Pathol; 2008 Feb; 214(3):387-93. PubMed ID: 18085521
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice.
    Kobayashi T; Minowa O; Sugitani Y; Takai S; Mitani H; Kobayashi E; Noda T; Hino O
    Proc Natl Acad Sci U S A; 2001 Jul; 98(15):8762-7. PubMed ID: 11438694
    [TBL] [Abstract][Full Text] [Related]  

  • 30. mTOR and P70 S6 kinase expression in primary liver neoplasms.
    Sahin F; Kannangai R; Adegbola O; Wang J; Su G; Torbenson M
    Clin Cancer Res; 2004 Dec; 10(24):8421-5. PubMed ID: 15623621
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Aberrant expression of HMGA2 in uterine leiomyoma associated with loss of TSC2 tumor suppressor gene function.
    Hunter DS; Klotzbücher M; Kugoh H; Cai SL; Mullen JP; Manfioletti G; Fuhrman U; Walker CL
    Cancer Res; 2002 Jul; 62(13):3766-72. PubMed ID: 12097287
    [TBL] [Abstract][Full Text] [Related]  

  • 32. AKT activation in human glioblastomas enhances proliferation via TSC2 and S6 kinase signaling.
    Riemenschneider MJ; Betensky RA; Pasedag SM; Louis DN
    Cancer Res; 2006 Jun; 66(11):5618-23. PubMed ID: 16740698
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer.
    Kobayashi T; Hirayama Y; Kobayashi E; Kubo Y; Hino O
    Nat Genet; 1995 Jan; 9(1):70-4. PubMed ID: 7704028
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras.
    Wislez M; Spencer ML; Izzo JG; Juroske DM; Balhara K; Cody DD; Price RE; Hittelman WN; Wistuba II; Kurie JM
    Cancer Res; 2005 Apr; 65(8):3226-35. PubMed ID: 15833854
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.
    Amornphimoltham P; Patel V; Sodhi A; Nikitakis NG; Sauk JJ; Sausville EA; Molinolo AA; Gutkind JS
    Cancer Res; 2005 Nov; 65(21):9953-61. PubMed ID: 16267020
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Regulation of microtubule-dependent protein transport by the TSC2/mammalian target of rapamycin pathway.
    Jiang X; Yeung RS
    Cancer Res; 2006 May; 66(10):5258-69. PubMed ID: 16707451
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
    Fang CX; Yang X; Sreejayan N; Ren J
    Exp Neurol; 2007 Jan; 203(1):196-204. PubMed ID: 16962100
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma.
    Wilson C; Idziaszczyk S; Parry L; Guy C; Griffiths DF; Lazda E; Bayne RA; Smith AJ; Sampson JR; Cheadle JP
    Hum Mol Genet; 2005 Jul; 14(13):1839-50. PubMed ID: 15888477
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM).
    Goncharova EA; Goncharov DA; Eszterhas A; Hunter DS; Glassberg MK; Yeung RS; Walker CL; Noonan D; Kwiatkowski DJ; Chou MM; Panettieri RA; Krymskaya VP
    J Biol Chem; 2002 Aug; 277(34):30958-67. PubMed ID: 12045200
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins.
    Xu Y; Chen SY; Ross KN; Balk SP
    Cancer Res; 2006 Aug; 66(15):7783-92. PubMed ID: 16885382
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.