369 related articles for article (PubMed ID: 14993223)
1. Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.
Twiddy D; Brown DG; Adrain C; Jukes R; Martin SJ; Cohen GM; MacFarlane M; Cain K
J Biol Chem; 2004 May; 279(19):19665-82. PubMed ID: 14993223
[TBL] [Abstract][Full Text] [Related]
2. Caspase-7 is directly activated by the approximately 700-kDa apoptosome complex and is released as a stable XIAP-caspase-7 approximately 200-kDa complex.
Twiddy D; Cohen GM; Macfarlane M; Cain K
J Biol Chem; 2006 Feb; 281(7):3876-88. PubMed ID: 16352606
[TBL] [Abstract][Full Text] [Related]
3. Chemical-induced apoptosis: formation of the Apaf-1 apoptosome.
Cain K
Drug Metab Rev; 2003 Nov; 35(4):337-63. PubMed ID: 14705865
[TBL] [Abstract][Full Text] [Related]
4. Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes.
Bratton SB; Walker G; Srinivasula SM; Sun XM; Butterworth M; Alnemri ES; Cohen GM
EMBO J; 2001 Mar; 20(5):998-1009. PubMed ID: 11230124
[TBL] [Abstract][Full Text] [Related]
5. Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes.
Hill MM; Adrain C; Duriez PJ; Creagh EM; Martin SJ
EMBO J; 2004 May; 23(10):2134-45. PubMed ID: 15103327
[TBL] [Abstract][Full Text] [Related]
6. Regulation of the Apaf-1/caspase-9 apoptosome by caspase-3 and XIAP.
Zou H; Yang R; Hao J; Wang J; Sun C; Fesik SW; Wu JC; Tomaselli KJ; Armstrong RC
J Biol Chem; 2003 Mar; 278(10):8091-8. PubMed ID: 12506111
[TBL] [Abstract][Full Text] [Related]
7. Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex.
Bratton SB; Walker G; Roberts DL; Cain K; Cohen GM
Cell Death Differ; 2001 Apr; 8(4):425-33. PubMed ID: 11550094
[TBL] [Abstract][Full Text] [Related]
8. The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis.
Lauber K; Appel HA; Schlosser SF; Gregor M; Schulze-Osthoff K; Wesselborg S
J Biol Chem; 2001 Aug; 276(32):29772-81. PubMed ID: 11387322
[TBL] [Abstract][Full Text] [Related]
9. Transforming growth factor-beta(1) induces apoptosis in rat FaO hepatoma cells via cytochrome c release and oligomerization of Apaf-1 to form a approximately 700-kd apoptosome caspase-processing complex.
Freathy C; Brown DG; Roberts RA; Cain K
Hepatology; 2000 Oct; 32(4 Pt 1):750-60. PubMed ID: 11003619
[TBL] [Abstract][Full Text] [Related]
10. Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.
Deming PB; Schafer ZT; Tashker JS; Potts MB; Deshmukh M; Kornbluth S
Mol Cell Biol; 2004 Dec; 24(23):10289-99. PubMed ID: 15542838
[TBL] [Abstract][Full Text] [Related]
11. Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9.
Noori AR; Tashakor A; Nikkhah M; Eriksson LA; Hosseinkhani S; Fearnhead HO
Biochimie; 2021 Jan; 180():23-29. PubMed ID: 33132160
[TBL] [Abstract][Full Text] [Related]
12. Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90.
Pandey P; Saleh A; Nakazawa A; Kumar S; Srinivasula SM; Kumar V; Weichselbaum R; Nalin C; Alnemri ES; Kufe D; Kharbanda S
EMBO J; 2000 Aug; 19(16):4310-22. PubMed ID: 10944114
[TBL] [Abstract][Full Text] [Related]
13. Structure of the apoptotic protease-activating factor 1 bound to ADP.
Riedl SJ; Li W; Chao Y; Schwarzenbacher R; Shi Y
Nature; 2005 Apr; 434(7035):926-33. PubMed ID: 15829969
[TBL] [Abstract][Full Text] [Related]
14. Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c.
Martin MC; Allan LA; Lickrish M; Sampson C; Morrice N; Clarke PR
J Biol Chem; 2005 Apr; 280(15):15449-55. PubMed ID: 15703181
[TBL] [Abstract][Full Text] [Related]
15. Negative regulation of the Apaf-1 apoptosome by Hsp70.
Saleh A; Srinivasula SM; Balkir L; Robbins PD; Alnemri ES
Nat Cell Biol; 2000 Aug; 2(8):476-83. PubMed ID: 10934467
[TBL] [Abstract][Full Text] [Related]
16. PSAP induces a unique Apaf-1 and Smac-dependent mitochondrial apoptotic pathway independent of Bcl-2 family proteins.
Li T; Zeng L; Gao W; Cui MZ; Fu X; Xu X
Biochim Biophys Acta; 2013 Mar; 1832(3):453-74. PubMed ID: 23207240
[TBL] [Abstract][Full Text] [Related]
17. Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1.
Kim HE; Du F; Fang M; Wang X
Proc Natl Acad Sci U S A; 2005 Dec; 102(49):17545-50. PubMed ID: 16251271
[TBL] [Abstract][Full Text] [Related]
18. XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis.
Bratton SB; Lewis J; Butterworth M; Duckett CS; Cohen GM
Cell Death Differ; 2002 Sep; 9(9):881-92. PubMed ID: 12181739
[TBL] [Abstract][Full Text] [Related]
19. Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein.
Fu J; Jin Y; Arend LJ
J Biol Chem; 2003 Dec; 278(52):52660-72. PubMed ID: 14523016
[TBL] [Abstract][Full Text] [Related]
20. Hsp72 inhibits apoptosis upstream of the mitochondria and not through interactions with Apaf-1.
Steel R; Doherty JP; Buzzard K; Clemons N; Hawkins CJ; Anderson RL
J Biol Chem; 2004 Dec; 279(49):51490-9. PubMed ID: 15371421
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
