BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 14998573)

  • 1. PAMPA--a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones.
    Bermejo M; Avdeef A; Ruiz A; Nalda R; Ruell JA; Tsinman O; González I; Fernández C; Sánchez G; Garrigues TM; Merino V
    Eur J Pharm Sci; 2004 Mar; 21(4):429-41. PubMed ID: 14998573
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PAMPA--a drug absorption in vitro model 11. Matching the in vivo unstirred water layer thickness by individual-well stirring in microtitre plates.
    Avdeef A; Nielsen PE; Tsinman O
    Eur J Pharm Sci; 2004 Aug; 22(5):365-74. PubMed ID: 15265506
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico prediction of human oral absorption based on QSAR analyses of PAMPA permeability.
    Akamatsu M; Fujikawa M; Nakao K; Shimizu R
    Chem Biodivers; 2009 Nov; 6(11):1845-66. PubMed ID: 19937826
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Caco-2 permeability of weakly basic drugs predicted with the double-sink PAMPA pKa(flux) method.
    Avdeef A; Artursson P; Neuhoff S; Lazorova L; Gråsjö J; Tavelin S
    Eur J Pharm Sci; 2005 Mar; 24(4):333-49. PubMed ID: 15734300
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability.
    Mensch J; Melis A; Mackie C; Verreck G; Brewster ME; Augustijns P
    Eur J Pharm Biopharm; 2010 Mar; 74(3):495-502. PubMed ID: 20067834
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Parallel artificial membrane permeability assay (PAMPA) combined with a 10-day multiscreen Caco-2 cell culture as a tool for assessing new drug candidates.
    Masungi C; Mensch J; Van Dijck A; Borremans C; Willems B; Mackie C; Noppe M; Brewster ME
    Pharmazie; 2008 Mar; 63(3):194-9. PubMed ID: 18444507
    [TBL] [Abstract][Full Text] [Related]  

  • 7. QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Fujikawa M; Nakao K; Shimizu R; Akamatsu M
    Bioorg Med Chem; 2007 Jun; 15(11):3756-67. PubMed ID: 17418579
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PAMPA--a drug absorption in vitro model. 5. Unstirred water layer in iso-pH mapping assays and pKa(flux)--optimized design (pOD-PAMPA).
    Ruell JA; Tsinman KL; Avdeef A
    Eur J Pharm Sci; 2003 Dec; 20(4-5):393-402. PubMed ID: 14659483
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Correlation between PAMPA permeability and cellular activities of hepatitis C virus protease inhibitors.
    Li C; Nair L; Liu T; Li F; Pichardo J; Agrawal S; Chase R; Tong X; Uss AS; Bogen S; Njoroge FG; Morrison RA; Cheng KC
    Biochem Pharmacol; 2008 Mar; 75(5):1186-97. PubMed ID: 18164692
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation with in vitro results.
    González-Alvarez I; Fernández-Teruel C; Casabó-Alós VG; Garrigues TM; Polli JE; Ruiz-García A; Bermejo M
    Biopharm Drug Dispos; 2007 Jul; 28(5):229-39. PubMed ID: 17410527
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PAMPA--a drug absorption in vitro model 8. Apparent filter porosity and the unstirred water layer.
    Nielsen PE; Avdeef A
    Eur J Pharm Sci; 2004 May; 22(1):33-41. PubMed ID: 15113581
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The effect of multiple N-methylation on intestinal permeability of cyclic hexapeptides.
    Ovadia O; Greenberg S; Chatterjee J; Laufer B; Opperer F; Kessler H; Gilon C; Hoffman A
    Mol Pharm; 2011 Apr; 8(2):479-87. PubMed ID: 21375270
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Relationships between structure and high-throughput screening permeability of diverse drugs with artificial membranes: application to prediction of Caco-2 cell permeability.
    Fujikawa M; Ano R; Nakao K; Shimizu R; Akamatsu M
    Bioorg Med Chem; 2005 Aug; 13(15):4721-32. PubMed ID: 15936203
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Correlation between epithelial cell permeability of cephalexin and expression of intestinal oligopeptide transporter.
    Chu XY; Sánchez-Castaño GP; Higaki K; Oh DM; Hsu CP; Amidon GL
    J Pharmacol Exp Ther; 2001 Nov; 299(2):575-82. PubMed ID: 11602669
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mathematical modelling of in situ and in vitro efflux of ciprofloxacin and grepafloxacin.
    Rodríguez-Ibáñez M; Sánchez-Castaño G; Montalar-Montero M; Garrigues TM; Bermejo M; Merino V
    Int J Pharm; 2006 Jan; 307(1):33-41. PubMed ID: 16257153
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Correlation of in vitro and in vivo models for the oral absorption of peptide drugs.
    Föger F; Kopf A; Loretz B; Albrecht K; Bernkop-Schnürch A
    Amino Acids; 2008 Jun; 35(1):233-41. PubMed ID: 17726639
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development and evaluation of an in vitro method for prediction of human drug absorption II. Demonstration of the method suitability.
    Corti G; Maestrelli F; Cirri M; Zerrouk N; Mura P
    Eur J Pharm Sci; 2006 Mar; 27(4):354-62. PubMed ID: 16364612
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Estimating human drug oral absorption kinetics from Caco-2 permeability using an absorption-disposition model: model development and evaluation and derivation of analytical solutions for k(a) and F(a).
    Usansky HH; Sinko PJ
    J Pharmacol Exp Ther; 2005 Jul; 314(1):391-9. PubMed ID: 15833900
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of Cassette PAMPA for Permeability Screening.
    Oh MH; Lee HJ; Jo SH; Park BB; Park SB; Kim EY; Zhou Y; Jeon YH; Lee K
    Biol Pharm Bull; 2017; 40(4):419-424. PubMed ID: 28381797
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Membrane permeability in the gastrointestinal tract: the interplay between microclimate pH and transporters.
    Kristl A
    Chem Biodivers; 2009 Nov; 6(11):1923-32. PubMed ID: 19937830
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.