371 related articles for article (PubMed ID: 15001968)
1. Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens.
von Richter O; Burk O; Fromm MF; Thon KP; Eichelbaum M; Kivistö KT
Clin Pharmacol Ther; 2004 Mar; 75(3):172-83. PubMed ID: 15001968
[TBL] [Abstract][Full Text] [Related]
2. Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5.
Mouly SJ; Matheny C; Paine MF; Smith G; Lamba J; Lamba V; Pusek SN; Schuetz EG; Stewart PW; Watkins PB
Clin Pharmacol Ther; 2005 Dec; 78(6):605-18. PubMed ID: 16338276
[TBL] [Abstract][Full Text] [Related]
3. Expression of cytochromes P450 3A and P-glycoprotein in human large intestine in paired tumour and normal samples.
Canaparo R; Nordmark A; Finnström N; Lundgren S; Seidegård J; Jeppsson B; Edwards RJ; Boobis AR; Rane A
Basic Clin Pharmacol Toxicol; 2007 Apr; 100(4):240-8. PubMed ID: 17371528
[TBL] [Abstract][Full Text] [Related]
4. Localization and mRNA expression of CYP3A and P-glycoprotein in human duodenum as a function of age.
Fakhoury M; Litalien C; Medard Y; Cavé H; Ezzahir N; Peuchmaur M; Jacqz-Aigrain E
Drug Metab Dispos; 2005 Nov; 33(11):1603-7. PubMed ID: 16049125
[TBL] [Abstract][Full Text] [Related]
5. Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.
Becquemont L; Glaeser H; Drescher S; Hitzl M; Simon N; Murdter TE; Heinkele G; Hofmann U; Schaefer C; Burk O; Verstuyft C; Eichelbaum M; Fromm MF
Clin Pharmacol Ther; 2006 May; 79(5):449-60. PubMed ID: 16678547
[TBL] [Abstract][Full Text] [Related]
6. CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies.
Engman HA; Lennernäs H; Taipalensuu J; Otter C; Leidvik B; Artursson P
J Pharm Sci; 2001 Nov; 90(11):1736-51. PubMed ID: 11745731
[TBL] [Abstract][Full Text] [Related]
7. Expression of CYP3A isoforms and P-glycoprotein in human stomach, jejunum and ileum.
Canaparo R; Finnström N; Serpe L; Nordmark A; Muntoni E; Eandi M; Rane A; Zara GP
Clin Exp Pharmacol Physiol; 2007 Nov; 34(11):1138-44. PubMed ID: 17880367
[TBL] [Abstract][Full Text] [Related]
8. St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4.
Dürr D; Stieger B; Kullak-Ublick GA; Rentsch KM; Steinert HC; Meier PJ; Fattinger K
Clin Pharmacol Ther; 2000 Dec; 68(6):598-604. PubMed ID: 11180019
[TBL] [Abstract][Full Text] [Related]
9. C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation.
Goto M; Masuda S; Saito H; Uemoto S; Kiuchi T; Tanaka K; Inui K
Pharmacogenetics; 2002 Aug; 12(6):451-7. PubMed ID: 12172213
[TBL] [Abstract][Full Text] [Related]
10. Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.
Lown KS; Bailey DG; Fontana RJ; Janardan SK; Adair CH; Fortlage LA; Brown MB; Guo W; Watkins PB
J Clin Invest; 1997 May; 99(10):2545-53. PubMed ID: 9153299
[TBL] [Abstract][Full Text] [Related]
11. Effect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass.
Bruyère A; Declèves X; Bouzom F; Ball K; Marques C; Treton X; Pocard M; Valleur P; Bouhnik Y; Panis Y; Scherrmann JM; Mouly S
Mol Pharm; 2010 Oct; 7(5):1596-607. PubMed ID: 20604570
[TBL] [Abstract][Full Text] [Related]
12. Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism.
Lin YS; Dowling AL; Quigley SD; Farin FM; Zhang J; Lamba J; Schuetz EG; Thummel KE
Mol Pharmacol; 2002 Jul; 62(1):162-72. PubMed ID: 12065767
[TBL] [Abstract][Full Text] [Related]
13. Hypericum perforatum: which constituents may induce intestinal MDR1 and CYP3A4 mRNA expression?
Gutmann H; Poller B; Büter KB; Pfrunder A; Schaffner W; Drewe J
Planta Med; 2006 Jun; 72(8):685-90. PubMed ID: 16755466
[TBL] [Abstract][Full Text] [Related]
14. Functional interaction of intestinal CYP3A4 and P-glycoprotein.
Kivistö KT; Niemi M; Fromm MF
Fundam Clin Pharmacol; 2004 Dec; 18(6):621-6. PubMed ID: 15548232
[TBL] [Abstract][Full Text] [Related]
15. Interplay of metabolism and transport in determining oral drug absorption and gut wall metabolism: a simulation assessment using the "Advanced Dissolution, Absorption, Metabolism (ADAM)" model.
Darwich AS; Neuhoff S; Jamei M; Rostami-Hodjegan A
Curr Drug Metab; 2010 Nov; 11(9):716-29. PubMed ID: 21189140
[TBL] [Abstract][Full Text] [Related]
16. MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype.
Lamba J; Strom S; Venkataramanan R; Thummel KE; Lin YS; Liu W; Cheng C; Lamba V; Watkins PB; Schuetz E
Clin Pharmacol Ther; 2006 Apr; 79(4):325-38. PubMed ID: 16580901
[TBL] [Abstract][Full Text] [Related]
17. Do men and women differ in proximal small intestinal CYP3A or P-glycoprotein expression?
Paine MF; Ludington SS; Chen ML; Stewart PW; Huang SM; Watkins PB
Drug Metab Dispos; 2005 Mar; 33(3):426-33. PubMed ID: 15608139
[TBL] [Abstract][Full Text] [Related]
18. Cytochrome P450 enzyme activity and protein expression in primary porcine enterocyte and hepatocyte cultures.
Hansen T; Borlak J; Bader A
Xenobiotica; 2000 Jan; 30(1):27-46. PubMed ID: 10659949
[TBL] [Abstract][Full Text] [Related]
19. Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.
Nakamura T; Sakaeda T; Horinouchi M; Tamura T; Aoyama N; Shirakawa T; Matsuo M; Kasuga M; Okumura K
Clin Pharmacol Ther; 2002 Apr; 71(4):297-303. PubMed ID: 11956513
[TBL] [Abstract][Full Text] [Related]
20. Induction of cytochrome P450 3A4 and P-glycoprotein by the isoxazolyl-penicillin antibiotic flucloxacillin.
Huwyler J; Wright MB; Gutmann H; Drewe J
Curr Drug Metab; 2006 Feb; 7(2):119-26. PubMed ID: 16472102
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
