BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 15004239)

  • 1. Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop.
    Mason JM; Morrison DJ; Bassit B; Dimri M; Band H; Licht JD; Gross I
    Mol Biol Cell; 2004 May; 15(5):2176-88. PubMed ID: 15004239
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cbl functions downstream of Src kinases in Fc gamma RI signaling in primary human macrophages.
    Erdreich-Epstein A; Liu M; Kant AM; Izadi KD; Nolta JA; Durden DL
    J Leukoc Biol; 1999 Apr; 65(4):523-34. PubMed ID: 10204582
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops.
    Rubin C; Litvak V; Medvedovsky H; Zwang Y; Lev S; Yarden Y
    Curr Biol; 2003 Feb; 13(4):297-307. PubMed ID: 12593795
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation.
    Haglund K; Schmidt MHH; Wong ES; Guy GR; Dikic I
    EMBO Rep; 2005 Jul; 6(7):635-41. PubMed ID: 15962011
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl.
    Wong A; Lamothe B; Lee A; Schlessinger J; Lax I
    Proc Natl Acad Sci U S A; 2002 May; 99(10):6684-9. PubMed ID: 11997436
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CrkL is a novel target of Sprouty2 in fibroblast growth factor signaling.
    Satoh T; Torii S; Nakayama K; Nishida E
    Genes Cells; 2010 Mar; 15(3):161-8. PubMed ID: 20136656
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A.
    Aranda S; Alvarez M; Turró S; Laguna A; de la Luna S
    Mol Cell Biol; 2008 Oct; 28(19):5899-911. PubMed ID: 18678649
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation.
    Kaabeche K; Lemonnier J; Le Mée S; Caverzasio J; Marie PJ
    J Biol Chem; 2004 Aug; 279(35):36259-67. PubMed ID: 15190072
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.
    Cross MJ; Lu L; Magnusson P; Nyqvist D; Holmqvist K; Welsh M; Claesson-Welsh L
    Mol Biol Cell; 2002 Aug; 13(8):2881-93. PubMed ID: 12181353
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FRS2-dependent SRC activation is required for fibroblast growth factor receptor-induced phosphorylation of Sprouty and suppression of ERK activity.
    Li X; Brunton VG; Burgar HR; Wheldon LM; Heath JK
    J Cell Sci; 2004 Dec; 117(Pt 25):6007-17. PubMed ID: 15564375
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of Sprouty2 stability by mammalian Seven-in-Absentia homolog 2.
    Nadeau RJ; Toher JL; Yang X; Kovalenko D; Friesel R
    J Cell Biochem; 2007 Jan; 100(1):151-60. PubMed ID: 16888801
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High affinity IgG receptor activation of Src family kinases is required for modulation of the Shc-Grb2-Sos complex and the downstream activation of the nicotinamide adenine dinucleotide phosphate (reduced) oxidase.
    Park RK; Erdreich-Epstein A; Liu M; Izadi KD; Durden DL
    J Immunol; 1999 Dec; 163(11):6023-34. PubMed ID: 10570290
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events.
    Schlaepfer DD; Jones KC; Hunter T
    Mol Cell Biol; 1998 May; 18(5):2571-85. PubMed ID: 9566877
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function.
    Fong CW; Leong HF; Wong ES; Lim J; Yusoff P; Guy GR
    J Biol Chem; 2003 Aug; 278(35):33456-64. PubMed ID: 12815057
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins.
    Ong SH; Hadari YR; Gotoh N; Guy GR; Schlessinger J; Lax I
    Proc Natl Acad Sci U S A; 2001 May; 98(11):6074-9. PubMed ID: 11353842
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors.
    Ong SH; Guy GR; Hadari YR; Laks S; Gotoh N; Schlessinger J; Lax I
    Mol Cell Biol; 2000 Feb; 20(3):979-89. PubMed ID: 10629055
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The protein product of the c-cbl oncogene rapidly complexes with the EGF receptor and is tyrosine phosphorylated following EGF stimulation.
    Bowtell DD; Langdon WY
    Oncogene; 1995 Oct; 11(8):1561-7. PubMed ID: 7478580
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling.
    Rorsman C; Tsioumpekou M; Heldin CH; Lennartsson J
    J Biol Chem; 2016 May; 291(22):11608-18. PubMed ID: 27048651
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tyrosine phosphorylation of p120cbl in BCR/abl transformed hematopoietic cells mediates enhanced association with phosphatidylinositol 3-kinase.
    Jain SK; Langdon WY; Varticovski L
    Oncogene; 1997 May; 14(18):2217-28. PubMed ID: 9174058
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.
    Chandramouli S; Yu CY; Yusoff P; Lao DH; Leong HF; Mizuno K; Guy GR
    J Biol Chem; 2008 Jan; 283(3):1679-1691. PubMed ID: 17974561
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.