217 related articles for article (PubMed ID: 15004527)
1. Ability of the activated PI3K/Akt oncoproteins to synergize with MEK1 and induce cell cycle progression and abrogate the cytokine-dependence of hematopoietic cells.
Shelton JG; Blalock WL; White ER; Steelman LS; McCubrey JA
Cell Cycle; 2004 Apr; 3(4):503-12. PubMed ID: 15004527
[TBL] [Abstract][Full Text] [Related]
2. Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.
Blalock WL; Navolanic PM; Steelman LS; Shelton JG; Moye PW; Lee JT; Franklin RA; Mirza A; McMahon M; White MK; McCubrey JA
Leukemia; 2003 Jun; 17(6):1058-67. PubMed ID: 12764369
[TBL] [Abstract][Full Text] [Related]
3. Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.
Blalock WL; Moye PW; Chang F; Pearce M; Steelman LS; McMahon M; McCubrey JA
Leukemia; 2000 Jun; 14(6):1080-96. PubMed ID: 10865974
[TBL] [Abstract][Full Text] [Related]
4. Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation.
Shelton JG; Moye PW; Steelman LS; Blalock WL; Lee JT; Franklin RA; McMahon M; McCubrey JA
Leukemia; 2003 Sep; 17(9):1765-82. PubMed ID: 12970777
[TBL] [Abstract][Full Text] [Related]
5. Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells.
Shelton JG; Steelman LS; Lee JT; Knapp SL; Blalock WL; Moye PW; Franklin RA; Pohnert SC; Mirza AM; McMahon M; McCubrey JA
Oncogene; 2003 Apr; 22(16):2478-92. PubMed ID: 12717425
[TBL] [Abstract][Full Text] [Related]
6. Synergy between PI3K/Akt and Raf/MEK/ERK pathways in IGF-1R mediated cell cycle progression and prevention of apoptosis in hematopoietic cells.
Shelton JG; Steelman LS; White ER; McCubrey JA
Cell Cycle; 2004 Mar; 3(3):372-9. PubMed ID: 14726697
[TBL] [Abstract][Full Text] [Related]
7. Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism.
Hoyle PE; Moye PW; Steelman LS; Blalock WL; Franklin RA; Pearce M; Cherwinski H; Bosch E; McMahon M; McCubrey JA
Leukemia; 2000 Apr; 14(4):642-56. PubMed ID: 10764150
[TBL] [Abstract][Full Text] [Related]
8. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
McCubrey JA; Steelman LS; Abrams SL; Lee JT; Chang F; Bertrand FE; Navolanic PM; Terrian DM; Franklin RA; D'Assoro AB; Salisbury JL; Mazzarino MC; Stivala F; Libra M
Adv Enzyme Regul; 2006; 46():249-79. PubMed ID: 16854453
[TBL] [Abstract][Full Text] [Related]
9. Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells.
Blalock WL; Pearce M; Chang F; Lee JT; Pohnert SC; Burrows C; Steelman LS; Franklin RA; McMahon M; McCubrey JA
Leukemia; 2001 May; 15(5):794-807. PubMed ID: 11368441
[TBL] [Abstract][Full Text] [Related]
10. Interactions between the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells.
McCubrey JA; Lee JT; Steelman LS; Blalock WL; Moye PW; Chang F; Pearce M; Shelton JG; White MK; Franklin RA; Pohnert SC
Cancer Detect Prev; 2001; 25(4):375-93. PubMed ID: 11531015
[TBL] [Abstract][Full Text] [Related]
11. A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells.
Blalock WL; Pearce M; Steelman LS; Franklin RA; McCarthy SA; Cherwinski H; McMahon M; McCubrey JA
Oncogene; 2000 Jan; 19(4):526-36. PubMed ID: 10698522
[TBL] [Abstract][Full Text] [Related]
12. Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells.
McCubrey JA; Steelman LS; Hoyle PE; Blalock WL; Weinstein-Oppenheimer C; Franklin RA; Cherwinski H; Bosch E; McMahon M
Leukemia; 1998 Dec; 12(12):1903-29. PubMed ID: 9844921
[TBL] [Abstract][Full Text] [Related]
13. Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs.
Steelman LS; Abrams SL; Shelton JG; Chappell WH; Bäsecke J; Stivala F; Donia M; Nicoletti F; Libra M; Martelli AM; McCubrey JA
Cell Cycle; 2010 Apr; 9(8):1629-38. PubMed ID: 20372086
[TBL] [Abstract][Full Text] [Related]
14. Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells.
Moye PW; Blalock WL; Hoyle PE; Chang F; Franklin RA; Weinstein-Oppenheimer C; Pearce M; Steelman L; McMahon M; McCubrey JA
Leukemia; 2000 Jun; 14(6):1060-79. PubMed ID: 10865973
[TBL] [Abstract][Full Text] [Related]
15. Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways.
Hahn M; Li W; Yu C; Rahmani M; Dent P; Grant S
Mol Cancer Ther; 2005 Mar; 4(3):457-70. PubMed ID: 15767555
[TBL] [Abstract][Full Text] [Related]
16. Both src-dependent and -independent mechanisms mediate phosphatidylinositol 3-kinase regulation of colony-stimulating factor 1-activated mitogen-activated protein kinases in myeloid progenitors.
Lee AW; States DJ
Mol Cell Biol; 2000 Sep; 20(18):6779-98. PubMed ID: 10958675
[TBL] [Abstract][Full Text] [Related]
17. PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cells.
Aksamitiene E; Kholodenko BN; Kolch W; Hoek JB; Kiyatkin A
Cell Signal; 2010 Sep; 22(9):1369-78. PubMed ID: 20471474
[TBL] [Abstract][Full Text] [Related]
18. CD28 costimulation mediates down-regulation of p27kip1 and cell cycle progression by activation of the PI3K/PKB signaling pathway in primary human T cells.
Appleman LJ; van Puijenbroek AA; Shu KM; Nadler LM; Boussiotis VA
J Immunol; 2002 Mar; 168(6):2729-36. PubMed ID: 11884439
[TBL] [Abstract][Full Text] [Related]
19. Effects of a conditionally active v-ErbB and an EGF-R inhibitor on transformation of NIH-3T3 cells and abrogation of cytokine dependency of hematopoietic cells.
McCubrey JA; Shelton JG; Steelman LS; Franklin RA; Sreevalsan T; McMahon M
Oncogene; 2004 Oct; 23(47):7810-20. PubMed ID: 15361836
[TBL] [Abstract][Full Text] [Related]
20. Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals.
von Gise A; Lorenz P; Wellbrock C; Hemmings B; Berberich-Siebelt F; Rapp UR; Troppmair J
Mol Cell Biol; 2001 Apr; 21(7):2324-36. PubMed ID: 11259582
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
