BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 15006697)

  • 21. Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.
    Guo Q; Sopher BL; Furukawa K; Pham DG; Robinson N; Martin GM; Mattson MP
    J Neurosci; 1997 Jun; 17(11):4212-22. PubMed ID: 9151738
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.
    Rivabene R; Visentin S; Piscopo P; De Nuccio C; Crestini A; Svetoni F; Rosa P; Confaloni A
    Exp Biol Med (Maywood); 2014 Feb; 239(2):213-24. PubMed ID: 24363250
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake.
    Brunello L; Zampese E; Florean C; Pozzan T; Pizzo P; Fasolato C
    J Cell Mol Med; 2009 Sep; 13(9B):3358-69. PubMed ID: 19382908
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Constitutive cAMP response element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP3R) Ca2+ signaling.
    Müller M; Cárdenas C; Mei L; Cheung KH; Foskett JK
    Proc Natl Acad Sci U S A; 2011 Aug; 108(32):13293-8. PubMed ID: 21784978
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Enhanced generation of intracellular Abeta42 amyloid peptide by mutation of presenilins PS1 and PS2.
    Takeda K; Araki W; Tabira T
    Eur J Neurosci; 2004 Jan; 19(2):258-264. PubMed ID: 14725619
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Presenilin-2 and Calcium Handling: Molecules, Organelles, Cells and Brain Networks.
    Pizzo P; Basso E; Filadi R; Greotti E; Leparulo A; Pendin D; Redolfi N; Rossini M; Vajente N; Pozzan T; Fasolato C
    Cells; 2020 Sep; 9(10):. PubMed ID: 32992716
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Alterations of the Endoplasmic Reticulum (ER) Calcium Signaling Molecular Components in Alzheimer's Disease.
    Chami M; Checler F
    Cells; 2020 Dec; 9(12):. PubMed ID: 33271984
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Presenilin-1 mutations associated with familial Alzheimer's disease do not disrupt protein transport from the endoplasmic reticulum to the Golgi apparatus.
    Tan Y; Hong J; Doan T; McConlogue L; Maltese WA
    Biochim Biophys Acta; 1998 Jul; 1407(1):69-78. PubMed ID: 9639678
    [TBL] [Abstract][Full Text] [Related]  

  • 29. G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.
    Chen WT; Hsieh YF; Huang YJ; Lin CC; Lin YT; Liu YC; Lien CC; Cheng IH
    Mol Neurobiol; 2015 Dec; 52(3):1835-1849. PubMed ID: 25394380
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Presenilin-2 mutations modulate amplitude and kinetics of inositol 1, 4,5-trisphosphate-mediated calcium signals.
    Leissring MA; Parker I; LaFerla FM
    J Biol Chem; 1999 Nov; 274(46):32535-8. PubMed ID: 10551803
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Familial Alzheimer's disease presenilin-2 mutants affect Ca
    Pendin D; Fasolato C; Basso E; Filadi R; Greotti E; Galla L; Gomiero C; Leparulo A; Redolfi N; Scremin E; Vajente N; Pozzan T; Pizzo P
    Aging Clin Exp Res; 2021 Jun; 33(6):1705-1708. PubMed ID: 31606858
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Loosening ER-Mitochondria Coupling by the Expression of the Presenilin 2 Loop Domain.
    Rossini M; García-Casas P; Filadi R; Pizzo P
    Cells; 2021 Aug; 10(8):. PubMed ID: 34440738
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Presenilins as endoplasmic reticulum calcium leak channels and Alzheimer's disease pathogenesis.
    Supnet C; Bezprozvanny I
    Sci China Life Sci; 2011 Aug; 54(8):744-51. PubMed ID: 21786197
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Presenilin 1 mutations linked to familial Alzheimer's disease increase the intracellular levels of amyloid beta-protein 1-42 and its N-terminally truncated variant(s) which are generated at distinct sites.
    Sudoh S; Kawamura Y; Sato S; Wang R; Saido TC; Oyama F; Sakaki Y; Komano H; Yanagisawa K
    J Neurochem; 1998 Oct; 71(4):1535-43. PubMed ID: 9751187
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Abeta42, presenilins, and Alzheimer's disease.
    Iwatsubo T
    Neurobiol Aging; 1998; 19(1 Suppl):S11-3. PubMed ID: 9562460
    [TBL] [Abstract][Full Text] [Related]  

  • 36. AMY plaques in familial AD: comparison with sporadic Alzheimer's disease.
    Lippa CF; Schmidt ML; Nee LE; Bird T; Nochlin D; Hulette C; Mori H; Lee VM; Trojanowski JQ
    Neurology; 2000 Jan; 54(1):100-4. PubMed ID: 10636133
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.
    Steiner H; Capell A; Leimer U; Haass C
    Eur Arch Psychiatry Clin Neurosci; 1999; 249(6):266-70. PubMed ID: 10653281
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.
    Ryazantseva M; Skobeleva K; Glushankova L; Kaznacheyeva E
    J Neurochem; 2016 Mar; 136(5):1085-95. PubMed ID: 26678016
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Fibroblasts from FAD-linked presenilin 1 mutations display a normal unfolded protein response but overproduce Abeta42 in response to tunicamycin.
    Piccini A; Fassio A; Pasqualetto E; Vitali A; Borghi R; Palmieri D; Nacmias B; Sorbi S; Sitia R; Tabaton M
    Neurobiol Dis; 2004 Mar; 15(2):380-6. PubMed ID: 15006708
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios.
    Walker ES; Martinez M; Brunkan AL; Goate A
    J Neurochem; 2005 Jan; 92(2):294-301. PubMed ID: 15663477
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.