BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1087 related articles for article (PubMed ID: 15014502)

  • 1. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase.
    Bashir T; Dorrello NV; Amador V; Guardavaccaro D; Pagano M
    Nature; 2004 Mar; 428(6979):190-3. PubMed ID: 15014502
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex.
    Wei W; Ayad NG; Wan Y; Zhang GJ; Kirschner MW; Kaelin WG
    Nature; 2004 Mar; 428(6979):194-8. PubMed ID: 15014503
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.
    Pavlides SC; Lecanda J; Daubriac J; Pandya UM; Gama P; Blank S; Mittal K; Shukla P; Gold LI
    Cell Cycle; 2016; 15(7):931-47. PubMed ID: 26963853
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localization.
    Bashir T; Pagan JK; Busino L; Pagano M
    Cell Cycle; 2010 Mar; 9(5):971-4. PubMed ID: 20160477
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.
    Bornstein G; Ganoth D; Hershko A
    Proc Natl Acad Sci U S A; 2006 Aug; 103(31):11515-20. PubMed ID: 16861300
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CD28 costimulation mediates transcription of SKP2 and CKS1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation.
    Appleman LJ; Chernova I; Li L; Boussiotis VA
    Cell Cycle; 2006 Sep; 5(18):2123-9. PubMed ID: 16969077
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.
    Huang KT; Pavlides SC; Lecanda J; Blank SV; Mittal KR; Gold LI
    PLoS One; 2012; 7(9):e46072. PubMed ID: 23029392
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer.
    Pavlides SC; Huang KT; Reid DA; Wu L; Blank SV; Mittal K; Guo L; Rothenberg E; Rueda B; Cardozo T; Gold LI
    Endocrinology; 2013 Nov; 154(11):4030-45. PubMed ID: 24035998
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase.
    Hao B; Zheng N; Schulman BA; Wu G; Miller JJ; Pagano M; Pavletich NP
    Mol Cell; 2005 Oct; 20(1):9-19. PubMed ID: 16209941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of ubiquitin ligase SCF(Skp2) by Cks1: insights from hydrogen exchange mass spectrometry.
    Yao ZP; Zhou M; Kelly SE; Seeliger MA; Robinson CV; Itzhaki LS
    J Mol Biol; 2006 Oct; 363(3):673-86. PubMed ID: 16979657
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis.
    Calvisi DF; Ladu S; Pinna F; Frau M; Tomasi ML; Sini M; Simile MM; Bonelli P; Muroni MR; Seddaiu MA; Lim DS; Feo F; Pascale RM
    Gastroenterology; 2009 Nov; 137(5):1816-26.e1-10. PubMed ID: 19686743
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Don't skip the G1 phase: how APC/CCdh1 keeps SCFSKP2 in check.
    Bashir T; Pagano M
    Cell Cycle; 2004 Jul; 3(7):850-2. PubMed ID: 15190201
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling.
    Wang W; Ungermannova D; Jin J; Harper JW; Liu X
    Oncogene; 2004 Feb; 23(5):1064-75. PubMed ID: 14676846
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression.
    Sørensen CS; Lukas C; Kramer ER; Peters JM; Bartek J; Lukas J
    Mol Cell Biol; 2001 Jun; 21(11):3692-703. PubMed ID: 11340163
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vorinostat enhances protein stability of p27 and p21 through negative regulation of Skp2 and Cks1 in human breast cancer cells.
    Uehara N; Yoshizawa K; Tsubura A
    Oncol Rep; 2012 Jul; 28(1):105-10. PubMed ID: 22484732
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway.
    Lisztwan J; Marti A; Sutterlüty H; Gstaiger M; Wirbelauer C; Krek W
    EMBO J; 1998 Jan; 17(2):368-83. PubMed ID: 9430629
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts.
    Wirbelauer C; Sutterlüty H; Blondel M; Gstaiger M; Peter M; Reymond F; Krek W
    EMBO J; 2000 Oct; 19(20):5362-75. PubMed ID: 11032804
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cdh1-anaphase-promoting complex targets Skp2 for destruction in transforming growth factor beta-induced growth inhibition.
    Liu W; Wu G; Li W; Lobur D; Wan Y
    Mol Cell Biol; 2007 Apr; 27(8):2967-79. PubMed ID: 17283060
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phase.
    Rodier G; Coulombe P; Tanguay PL; Boutonnet C; Meloche S
    EMBO J; 2008 Feb; 27(4):679-91. PubMed ID: 18239684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Up-regulation of Cks1 and Skp2 with TNFα/NF-κB signaling in chronic progressive nephropathy.
    Suzuki S; Fukasawa H; Misaki T; Togawa A; Ohashi N; Kitagawa K; Kotake Y; Niida H; Hishida A; Yamamoto T; Kitagawa M
    Genes Cells; 2011 Nov; 16(11):1110-20. PubMed ID: 22017545
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 55.