These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 15016840)

  • 1. Insight into mutation-induced activation of the luteinizing hormone receptor: molecular simulations predict the functional behavior of engineered mutants at M398.
    Fanelli F; Verhoef-Post M; Timmerman M; Zeilemaker A; Martens JW; Themmen AP
    Mol Endocrinol; 2004 Jun; 18(6):1499-508. PubMed ID: 15016840
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The formation of a salt bridge between helices 3 and 6 is responsible for the constitutive activity and lack of hormone responsiveness of the naturally occurring L457R mutation of the human lutropin receptor.
    Zhang M; Mizrachi D; Fanelli F; Segaloff DL
    J Biol Chem; 2005 Jul; 280(28):26169-76. PubMed ID: 15908694
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Contributions of intracellular loops 2 and 3 of the lutropin receptor in Gs coupling.
    Angelova K; Fanelli F; Puett D
    Mol Endocrinol; 2008 Jan; 22(1):126-38. PubMed ID: 17872379
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A model for constitutive lutropin receptor activation based on molecular simulation and engineered mutations in transmembrane helices 6 and 7.
    Angelova K; Fanelli F; Puett D
    J Biol Chem; 2002 Aug; 277(35):32202-13. PubMed ID: 12070159
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional role of transmembrane helix 7 in the activation of the heptahelical lutropin receptor.
    Angelova K; Narayan P; Simon JP; Puett D
    Mol Endocrinol; 2000 Apr; 14(4):459-71. PubMed ID: 10770485
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insight into thyrotropin receptor cleavage by engineering the single polypeptide chain luteinizing hormone receptor into a cleaving, two subunit receptor.
    Chazenbalk GD; McLachlan SM; Chen CR; Rapoport B
    Eur J Biochem; 2001 Apr; 268(8):2261-9. PubMed ID: 11298743
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pleiotropic effects of substitutions of a highly conserved leucine in transmembrane helix III of the human lutropin/choriogonadotropin receptor with respect to constitutive activation and hormone responsiveness.
    Shinozaki H; Fanelli F; Liu X; Jaquette J; Nakamura K; Segaloff DL
    Mol Endocrinol; 2001 Jun; 15(6):972-84. PubMed ID: 11376115
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor.
    Urizar E; Claeysen S; Deupí X; Govaerts C; Costagliola S; Vassart G; Pardo L
    J Biol Chem; 2005 Apr; 280(17):17135-41. PubMed ID: 15722344
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential responses of an invariant region in the ectodomain of three glycoprotein hormone receptors to mutagenesis and assay conditions.
    Angelova K; Puett D
    Endocrine; 2002 Nov; 19(2):147-54. PubMed ID: 12588044
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence for an important functional role of intracellular loop II of the lutropin receptor.
    Fernandez LM; Puett D
    Mol Cell Endocrinol; 1997 Apr; 128(1-2):161-9. PubMed ID: 9140087
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and modeling.
    Bhowmick N; Huang J; Puett D; Isaacs NW; Lapthorn AJ
    Mol Endocrinol; 1996 Sep; 10(9):1147-59. PubMed ID: 8885249
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Analysis of the third transmembrane domain of the human type 1 angiotensin II receptor by cysteine scanning mutagenesis.
    Martin SS; Boucard AA; Clément M; Escher E; Leduc R; Guillemette G
    J Biol Chem; 2004 Dec; 279(49):51415-23. PubMed ID: 15452107
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The luteinizing hormone receptor: influence of buffer composition on ligand binding and signaling of wild type and mutant receptors.
    Angelova K; Narayan P; Puett D
    Mol Cell Endocrinol; 2003 Jun; 204(1-2):1-9. PubMed ID: 12850276
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of a region of the lutropin receptor extracellular domain near transmembrane helix 1 that is important in ligand-mediated signaling.
    Alvarez CA; Narayan P; Huang J; Puett D
    Endocrinology; 1999 Apr; 140(4):1775-82. PubMed ID: 10098515
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor. Identification of a novel "locked-on" phenotype and double revertant mutations.
    Prioleau C; Visiers I; Ebersole BJ; Weinstein H; Sealfon SC
    J Biol Chem; 2002 Sep; 277(39):36577-84. PubMed ID: 12145300
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of two amino acid residues on the extracellular domain of the lutropin/choriogonadotropin receptor important in signaling.
    Huang J; Puett D
    J Biol Chem; 1995 Dec; 270(50):30023-8. PubMed ID: 8530405
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Constitutive activation of the angiotensin II type 1 receptor alters the spatial proximity of transmembrane 7 to the ligand-binding pocket.
    Boucard AA; Roy M; Beaulieu ME; Lavigne P; Escher E; Guillemette G; Leduc R
    J Biol Chem; 2003 Sep; 278(38):36628-36. PubMed ID: 12842881
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of amino acid residues in transmembrane helices VI and VII of the lutropin/choriogonadotropin receptor involved in signaling.
    Fernandez LM; Puett D
    Biochemistry; 1996 Apr; 35(13):3986-93. PubMed ID: 8672431
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Conserved amino acids participate in the structure networks deputed to intramolecular communication in the lutropin receptor.
    Angelova K; Felline A; Lee M; Patel M; Puett D; Fanelli F
    Cell Mol Life Sci; 2011 Apr; 68(7):1227-39. PubMed ID: 20835841
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural requirements for mutational lutropin/choriogonadotropin receptor activation.
    Sangkuhl K; Schulz A; Schultz G; Schöneberg T
    J Biol Chem; 2002 Dec; 277(49):47748-55. PubMed ID: 12356766
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.