BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 15023072)

  • 1. Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates.
    Kovarik Z; Radić Z; Berman HA; Simeon-Rudolf V; Reiner E; Taylor P
    Biochemistry; 2004 Mar; 43(11):3222-9. PubMed ID: 15023072
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of oxime reactivation of acetylcholinesterase analyzed by chirality and mutagenesis.
    Wong L; Radic Z; Brüggemann RJ; Hosea N; Berman HA; Taylor P
    Biochemistry; 2000 May; 39(19):5750-7. PubMed ID: 10801325
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphoryl oxime inhibition of acetylcholinesterase during oxime reactivation is prevented by edrophonium.
    Luo C; Saxena A; Smith M; Garcia G; Radić Z; Taylor P; Doctor BP
    Biochemistry; 1999 Aug; 38(31):9937-47. PubMed ID: 10433700
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol.
    Bosak A; Gazić I; Vinković V; Kovarik Z
    Arch Biochem Biophys; 2008 Mar; 471(1):72-6. PubMed ID: 18167304
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutation of acetylcholinesterase to enhance oxime-assisted catalytic turnover of methylphosphonates.
    Kovarik Z; Radić Z; Berman HA; Taylor P
    Toxicology; 2007 Apr; 233(1-3):79-84. PubMed ID: 17046138
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Active site mutant acetylcholinesterase interactions with 2-PAM, HI-6, and DDVP.
    Kovarik Z; Ciban N; Radić Z; Simeon-Rudolf V; Taylor P
    Biochem Biophys Res Commun; 2006 Apr; 342(3):973-8. PubMed ID: 16598855
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Acetylcholinesterase active centre and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates.
    Kovarik Z; Radić Z; Berman HA; Simeon-Rudolf V; Reiner E; Taylor P
    Biochem J; 2003 Jul; 373(Pt 1):33-40. PubMed ID: 12665427
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interactions of oxime reactivators with diethylphosphoryl adducts of human acetylcholinesterase and its mutant derivatives.
    Grosfeld H; Barak D; Ordentlich A; Velan B; Shafferman A
    Mol Pharmacol; 1996 Sep; 50(3):639-49. PubMed ID: 8794905
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase.
    Bartling A; Worek F; Szinicz L; Thiermann H
    Toxicology; 2007 Apr; 233(1-3):166-72. PubMed ID: 16904809
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase.
    Kovarik Z; Maček Hrvat N; Kalisiak J; Katalinić M; Sit RK; Zorbaz T; Radić Z; Fokin VV; Sharpless KB; Taylor P
    Toxicol Appl Pharmacol; 2019 Jun; 372():40-46. PubMed ID: 30978400
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase.
    Mazor O; Cohen O; Kronman C; Raveh L; Stein D; Ordentlich A; Shafferman A
    Mol Pharmacol; 2008 Sep; 74(3):755-63. PubMed ID: 18523134
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Why acetylcholinesterase reactivators do not work in butyrylcholinesterase.
    Wiesner J; Kríz Z; Kuca K; Jun D; Koca J
    J Enzyme Inhib Med Chem; 2010 Jun; 25(3):318-22. PubMed ID: 19874115
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging.
    Cochran R; Kalisiak J; Küçükkilinç T; Radic Z; Garcia E; Zhang L; Ho KY; Amitai G; Kovarik Z; Fokin VV; Sharpless KB; Taylor P
    J Biol Chem; 2011 Aug; 286(34):29718-24. PubMed ID: 21730071
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The reactivation of tabun-inhibited mutant AChE with Ortho-7: steered molecular dynamics and quantum chemical studies.
    Lo R; Chandar NB; Ghosh S; Ganguly B
    Mol Biosyst; 2016 Apr; 12(4):1224-31. PubMed ID: 26879641
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Amino acid residues controlling reactivation of organophosphonyl conjugates of acetylcholinesterase by mono- and bisquaternary oximes.
    Ashani Y; Radić Z; Tsigelny I; Vellom DC; Pickering NA; Quinn DM; Doctor BP; Taylor P
    J Biol Chem; 1995 Mar; 270(11):6370-80. PubMed ID: 7890775
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Exploring the active center of human acetylcholinesterase with stereomers of an organophosphorus inhibitor with two chiral centers.
    Ordentlich A; Barak D; Kronman C; Benschop HP; De Jong LP; Ariel N; Barak R; Segall Y; Velan B; Shafferman A
    Biochemistry; 1999 Mar; 38(10):3055-66. PubMed ID: 10074358
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In silico studies on the role of mutant Y337A to reactivate tabun inhibited mAChE with K048.
    Chandar NB; Ghosh S; Lo R; Banjo S; Ganguly B
    Chem Biol Interact; 2015 Dec; 242():299-306. PubMed ID: 26494532
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: a kinetic analysis.
    Aurbek N; Thiermann H; Eyer F; Eyer P; Worek F
    Toxicology; 2009 May; 259(3):133-9. PubMed ID: 19428953
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
    Carletti E; Aurbek N; Gillon E; Loiodice M; Nicolet Y; Fontecilla-Camps JC; Masson P; Thiermann H; Nachon F; Worek F
    Biochem J; 2009 Jun; 421(1):97-106. PubMed ID: 19368529
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Specificity and orientation of trigonal carboxyl esters and tetrahedral alkylphosphonyl esters in cholinesterases.
    Hosea NA; Berman HA; Taylor P
    Biochemistry; 1995 Sep; 34(36):11528-36. PubMed ID: 7547883
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.