BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 15024078)

  • 1. Growth factor-mediated induction of HDM2 positively regulates hypoxia-inducible factor 1alpha expression.
    Bárdos JI; Chau NM; Ashcroft M
    Mol Cell Biol; 2004 Apr; 24(7):2905-14. PubMed ID: 15024078
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways.
    Shi YH; Wang YX; Bingle L; Gong LH; Heng WJ; Li Y; Fang WG
    J Pathol; 2005 Mar; 205(4):530-6. PubMed ID: 15714461
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling.
    Skinner HD; Zheng JZ; Fang J; Agani F; Jiang BH
    J Biol Chem; 2004 Oct; 279(44):45643-51. PubMed ID: 15337760
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.
    Mabjeesh NJ; Willard MT; Frederickson CE; Zhong H; Simons JW
    Clin Cancer Res; 2003 Jul; 9(7):2416-25. PubMed ID: 12855613
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells.
    Mottet D; Dumont V; Deccache Y; Demazy C; Ninane N; Raes M; Michiels C
    J Biol Chem; 2003 Aug; 278(33):31277-85. PubMed ID: 12764143
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells.
    Li YM; Zhou BP; Deng J; Pan Y; Hay N; Hung MC
    Cancer Res; 2005 Apr; 65(8):3257-63. PubMed ID: 15833858
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation.
    Alam H; Maizels ET; Park Y; Ghaey S; Feiger ZJ; Chandel NS; Hunzicker-Dunn M
    J Biol Chem; 2004 May; 279(19):19431-40. PubMed ID: 14982927
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
    Zhong H; Chiles K; Feldser D; Laughner E; Hanrahan C; Georgescu MM; Simons JW; Semenza GL
    Cancer Res; 2000 Mar; 60(6):1541-5. PubMed ID: 10749120
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Apigenin inhibits VEGF and HIF-1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways.
    Fang J; Xia C; Cao Z; Zheng JZ; Reed E; Jiang BH
    FASEB J; 2005 Mar; 19(3):342-53. PubMed ID: 15746177
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional regulation of plasminogen activator inhibitor-1 expression by insulin-like growth factor-1 via MAP kinases and hypoxia-inducible factor-1 in HepG2 cells.
    Dimova EY; Möller U; Herzig S; Fink T; Zachar V; Ebbesen P; Kietzmann T
    Thromb Haemost; 2005 Jun; 93(6):1176-84. PubMed ID: 15968405
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression.
    Laughner E; Taghavi P; Chiles K; Mahon PC; Semenza GL
    Mol Cell Biol; 2001 Jun; 21(12):3995-4004. PubMed ID: 11359907
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.
    Treins C; Giorgetti-Peraldi S; Murdaca J; Semenza GL; Van Obberghen E
    J Biol Chem; 2002 Aug; 277(31):27975-81. PubMed ID: 12032158
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypoxia-independent overexpression of hypoxia-inducible factor 1alpha as an early change in mouse hepatocarcinogenesis.
    Tanaka H; Yamamoto M; Hashimoto N; Miyakoshi M; Tamakawa S; Yoshie M; Tokusashi Y; Yokoyama K; Yaginuma Y; Ogawa K
    Cancer Res; 2006 Dec; 66(23):11263-70. PubMed ID: 17145871
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1.
    Jiang BH; Jiang G; Zheng JZ; Lu Z; Hunter T; Vogt PK
    Cell Growth Differ; 2001 Jul; 12(7):363-9. PubMed ID: 11457733
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.
    Zhou J; Schmid T; Frank R; Brüne B
    J Biol Chem; 2004 Apr; 279(14):13506-13. PubMed ID: 14726529
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 4-Hydroxy estradiol but not 2-hydroxy estradiol induces expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor A through phosphatidylinositol 3-kinase/Akt/FRAP pathway in OVCAR-3 and A2780-CP70 human ovarian carcinoma cells.
    Gao N; Nester RA; Sarkar MA
    Toxicol Appl Pharmacol; 2004 Apr; 196(1):124-35. PubMed ID: 15050414
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nutlin-3, an Hdm2 antagonist, inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated inactivation of HIF-1alpha.
    Lee YM; Lim JH; Chun YS; Moon HE; Lee MK; Huang LE; Park JW
    Carcinogenesis; 2009 Oct; 30(10):1768-75. PubMed ID: 19696166
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia.
    Suzuki H; Tomida A; Tsuruo T
    Oncogene; 2001 Sep; 20(41):5779-88. PubMed ID: 11593383
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.
    Alvarez-Tejado M; Alfranca A; Aragonés J; Vara A; Landázuri MO; del Peso L
    J Biol Chem; 2002 Apr; 277(16):13508-17. PubMed ID: 11815624
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.