BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1396 related articles for article (PubMed ID: 15028262)

  • 21. Cytotoxicities and structure-activity relationships of natural and unnatural lamellarins toward cancer cell lines.
    Chittchang M; Batsomboon P; Ruchirawat S; Ploypradith P
    ChemMedChem; 2009 Mar; 4(3):457-65. PubMed ID: 19152364
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis and anticancer activity of simplified indenoisoquinoline topoisomerase I inhibitors lacking substituents on the aromatic rings.
    Nagarajan M; Morrell A; Fort BC; Meckley MR; Antony S; Kohlhagen G; Pommier Y; Cushman M
    J Med Chem; 2004 Nov; 47(23):5651-61. PubMed ID: 15509164
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Total synthesis and evaluation of lamellarin alpha 20-Sulfate analogues.
    Ridley CP; Reddy MV; Rocha G; Bushman FD; Faulkner DJ
    Bioorg Med Chem; 2002 Oct; 10(10):3285-90. PubMed ID: 12150874
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and antitumor activity of simplified ecteinascidin-saframycin analogs.
    Liu ZZ; Wang Y; Tang YF; Chen SZ; Chen XG; Li HY
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1282-5. PubMed ID: 16338237
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors.
    Arepalli SK; Lee C; Sim S; Lee K; Jo H; Jun KY; Kwon Y; Kang JS; Jung JK; Lee H
    Bioorg Med Chem; 2018 Oct; 26(18):5181-5193. PubMed ID: 30253887
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Recent advances in lamellarin alkaloids: isolation, synthesis and activity.
    Pla D; Albericio F; Alvarez M
    Anticancer Agents Med Chem; 2008 Oct; 8(7):746-60. PubMed ID: 18855577
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Chemistry of Ecteinascidins. Part 5: An Additional Proof of Cytotoxicity Evaluation of Ecteinascidin 770 Derivatives.
    Toyoshima R; Mori N; Suzuki T; Lowtangkitcharoen W; Suwanborirux K; Saito N
    Chem Pharm Bull (Tokyo); 2016; 64(7):966-9. PubMed ID: 27373655
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis and biological evaluations of novel indenoisoquinolines as topoisomerase I inhibitors.
    Zhang X; Wang R; Zhao L; Lu N; Wang J; You Q; Li Z; Guo Q
    Bioorg Med Chem Lett; 2012 Jan; 22(2):1276-81. PubMed ID: 22079759
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Anticancer properties of lamellarins.
    Bailly C
    Mar Drugs; 2015 Feb; 13(3):1105-23. PubMed ID: 25706633
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks.
    Bailly C; Lansiaux A; Dassonneville L; Demarquay D; Coulomb H; Huchet M; Lavergne O; Bigg DC
    Biochemistry; 1999 Nov; 38(47):15556-63. PubMed ID: 10569939
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors.
    Seol Y; Zhang H; Agama K; Lorence N; Pommier Y; Neuman KC
    Mol Cancer Ther; 2015 Nov; 14(11):2552-9. PubMed ID: 26351326
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Optimization of the indenone ring of indenoisoquinoline topoisomerase I inhibitors.
    Morrell A; Placzek M; Parmley S; Grella B; Antony S; Pommier Y; Cushman M
    J Med Chem; 2007 Sep; 50(18):4388-404. PubMed ID: 17676830
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design, synthesis, and biological evaluation of indenoisoquinoline topoisomerase I inhibitors featuring polyamine side chains on the lactam nitrogen.
    Nagarajan M; Xiao X; Antony S; Kohlhagen G; Pommier Y; Cushman M
    J Med Chem; 2003 Dec; 46(26):5712-24. PubMed ID: 14667224
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors.
    Khadka DB; Park S; Jin Y; Han J; Kwon Y; Cho WJ
    Eur J Med Chem; 2018 Jan; 143():200-215. PubMed ID: 29174815
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Inhibition of mitochondrial respiration mediates apoptosis induced by the anti-tumoral alkaloid lamellarin D.
    Ballot C; Kluza J; Lancel S; Martoriati A; Hassoun SM; Mortier L; Vienne JC; Briand G; Formstecher P; Bailly C; Nevière R; Marchetti P
    Apoptosis; 2010 Jul; 15(7):769-81. PubMed ID: 20151196
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis, cytotoxicity and topoisomerase inhibition properties of multifarious aminoalkylated indeno[1,2-c]isoquinolin-5,11-diones.
    Ahn G; Schifano-Faux N; Goossens JF; Baldeyrou B; Couture A; Grandclaudon P; Lansiaux A; Ryckebusch A
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2259-63. PubMed ID: 21439821
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis, cytotoxicity, DNA interaction, and topoisomerase II inhibition properties of novel indeno[2,1-c]quinolin-7-one and indeno[1,2-c]isoquinolin-5,11-dione derivatives.
    Ryckebusch A; Garcin D; Lansiaux A; Goossens JF; Baldeyrou B; Houssin R; Bailly C; Hénichart JP
    J Med Chem; 2008 Jun; 51(12):3617-29. PubMed ID: 18507368
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design, synthesis and biological evaluation of 3-substituted indenoisoquinoline derivatives as topoisomerase I inhibitors.
    Zhao Q; Xu X; Xie Z; Liu X; You Q; Guo Q; Zhong Y; Li Z
    Bioorg Med Chem Lett; 2016 Feb; 26(3):1068-1072. PubMed ID: 26725027
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Antitumor agents. 3. Design, synthesis, and biological evaluation of new pyridoisoquinolindione and dihydrothienoquinolindione derivatives with potent cytotoxic activity.
    Bolognese A; Correale G; Manfra M; Lavecchia A; Mazzoni O; Novellino E; La Colla P; Sanna G; Loddo R
    J Med Chem; 2004 Feb; 47(4):849-58. PubMed ID: 14761187
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Chemistry of ecteinascidins. Part 3: preparation of 2'-N-acyl derivatives of ecteinascidin 770 and evaluation of cytotoxicity.
    Saktrakulkla P; Toriumi S; Tsujimoto M; Patarapanich C; Suwanborirux K; Saito N
    Bioorg Med Chem; 2011 Aug; 19(15):4421-36. PubMed ID: 21752654
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 70.