BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 15032673)

  • 1. Targeting FLT3 kinase in acute myelogenous leukemia: progress, perils, and prospects.
    Heinrich MC
    Mini Rev Med Chem; 2004 Mar; 4(3):255-71. PubMed ID: 15032673
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Therapeutic intervention in leukemias that express the activated fms-like tyrosine kinase 3 (FLT3): opportunities and challenges.
    Sternberg DW; Licht JD
    Curr Opin Hematol; 2005 Jan; 12(1):7-13. PubMed ID: 15604885
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Flt3 in acute myelogenous leukemia: biology, prognosis, and therapeutic implications.
    Voutsadakis IA
    Med Oncol; 2003; 20(4):311-24. PubMed ID: 14716027
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small molecule FLT3 tyrosine kinase inhibitors.
    Levis M; Small D
    Curr Pharm Des; 2004; 10(11):1183-93. PubMed ID: 15078134
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel FLT3 tyrosine kinase inhibitors.
    Levis M; Small D
    Expert Opin Investig Drugs; 2003 Dec; 12(12):1951-62. PubMed ID: 14640939
    [TBL] [Abstract][Full Text] [Related]  

  • 6. FLT3 Inhibitors in the Treatment of AML.
    Gilliland DG
    Clin Adv Hematol Oncol; 2004 Nov; 2(11):708-10. PubMed ID: 16163256
    [No Abstract]   [Full Text] [Related]  

  • 7. Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia.
    Lee-Sherick AB; Zhang W; Menachof KK; Hill AA; Rinella S; Kirkpatrick G; Page LS; Stashko MA; Jordan CT; Wei Q; Liu J; Zhang D; DeRyckere D; Wang X; Frye S; Earp HS; Graham DK
    Oncotarget; 2015 Mar; 6(9):6722-36. PubMed ID: 25762638
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Mutations of the gene coding for the receptor tyrosine kinase FLT3 in acute myeloid leukemia. Significance as the disease-specific molecular marker for diagnosis, prognosis and innovative therapy approaches].
    Spiekermann K; Hiddemann W; Schnittger S
    Dtsch Med Wochenschr; 2005 Apr; 130(16):1020-5. PubMed ID: 15830315
    [No Abstract]   [Full Text] [Related]  

  • 9. FLT3-activating mutations in acute promyelocytic leukaemia: a rationale for risk-adapted therapy with FLT3 inhibitors.
    Gilliland DG
    Best Pract Res Clin Haematol; 2003 Sep; 16(3):409-17. PubMed ID: 12935959
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CHIR-258: a potent inhibitor of FLT3 kinase in experimental tumor xenograft models of human acute myelogenous leukemia.
    Lopes de Menezes DE; Peng J; Garrett EN; Louie SG; Lee SH; Wiesmann M; Tang Y; Shephard L; Goldbeck C; Oei Y; Ye H; Aukerman SL; Heise C
    Clin Cancer Res; 2005 Jul; 11(14):5281-91. PubMed ID: 16033847
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FLT3 and its role in the pathogenesis of acute myeloid leukaemia.
    Reilly JT
    Leuk Lymphoma; 2003 Jan; 44(1):1-7. PubMed ID: 12691136
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PKC 412 FLT3 inhibitor therapy in AML: results of a phase II trial.
    Stone RM; De Angelo J; Galinsky I; Estey E; Klimek V; Grandin W; Lebwohl D; Yap A; Cohen P; Fox E; Neuberg D; Clark J; Gilliland DG; Griffin JD
    Ann Hematol; 2004; 83 Suppl 1():S89-90. PubMed ID: 15124689
    [No Abstract]   [Full Text] [Related]  

  • 13. An innovative phase I clinical study demonstrates inhibition of FLT3 phosphorylation by SU11248 in acute myeloid leukemia patients.
    O'Farrell AM; Foran JM; Fiedler W; Serve H; Paquette RL; Cooper MA; Yuen HA; Louie SG; Kim H; Nicholas S; Heinrich MC; Berdel WE; Bello C; Jacobs M; Scigalla P; Manning WC; Kelsey S; Cherrington JM
    Clin Cancer Res; 2003 Nov; 9(15):5465-76. PubMed ID: 14654525
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FLT3 in human hematologic malignancies.
    Kiyoi H; Naoe T
    Leuk Lymphoma; 2002 Aug; 43(8):1541-7. PubMed ID: 12400596
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prediction of resistance to small molecule FLT3 inhibitors: implications for molecularly targeted therapy of acute leukemia.
    Cools J; Mentens N; Furet P; Fabbro D; Clark JJ; Griffin JD; Marynen P; Gilliland DG
    Cancer Res; 2004 Sep; 64(18):6385-9. PubMed ID: 15374944
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia.
    Spiekermann K; Bagrintseva K; Schoch C; Haferlach T; Hiddemann W; Schnittger S
    Blood; 2002 Nov; 100(9):3423-5. PubMed ID: 12384447
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412.
    Stone RM; DeAngelo DJ; Klimek V; Galinsky I; Estey E; Nimer SD; Grandin W; Lebwohl D; Wang Y; Cohen P; Fox EA; Neuberg D; Clark J; Gilliland DG; Griffin JD
    Blood; 2005 Jan; 105(1):54-60. PubMed ID: 15345597
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitory anti-FLT3 antibodies are capable of mediating antibody-dependent cell-mediated cytotoxicity and reducing engraftment of acute myelogenous leukemia blasts in nonobese diabetic/severe combined immunodeficient mice.
    Piloto O; Levis M; Huso D; Li Y; Li H; Wang MN; Bassi R; Balderes P; Ludwig DL; Witte L; Zhu Z; Hicklin DJ; Small D
    Cancer Res; 2005 Feb; 65(4):1514-22. PubMed ID: 15735040
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia.
    Smith BD; Levis M; Beran M; Giles F; Kantarjian H; Berg K; Murphy KM; Dauses T; Allebach J; Small D
    Blood; 2004 May; 103(10):3669-76. PubMed ID: 14726387
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RNAi-induced down-regulation of FLT3 expression in AML cell lines increases sensitivity to MLN518.
    Walters DK; Stoffregen EP; Heinrich MC; Deininger MW; Druker BJ
    Blood; 2005 Apr; 105(7):2952-4. PubMed ID: 15585651
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.