BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 15033391)

  • 1. Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist.
    Hancock AA; Bennani YL; Bush EN; Esbenshade TA; Faghih R; Fox GB; Jacobson P; Knourek-Segel V; Krueger KM; Nuss ME; Pan JB; Shapiro R; Witte DG; Yao BB
    Eur J Pharmacol; 2004 Mar; 487(1-3):183-97. PubMed ID: 15033391
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro optimization of structure activity relationships of analogues of A-331440 combining radioligand receptor binding assays and micronucleus assays of potential antiobesity histamine H3 receptor antagonists.
    Hancock AA; Diehl MS; Faghih R; Bush EN; Krueger KM; Krishna G; Miller TR; Wilcox DM; Nguyen P; Pratt JK; Cowart MD; Esbenshade TA; Jacobson PB
    Basic Clin Pharmacol Toxicol; 2004 Sep; 95(3):144-52. PubMed ID: 15447739
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist.
    Esbenshade TA; Fox GB; Krueger KM; Baranowski JL; Miller TR; Kang CH; Denny LI; Witte DG; Yao BB; Pan JB; Faghih R; Bennani YL; Williams M; Hancock AA
    Biochem Pharmacol; 2004 Sep; 68(5):933-45. PubMed ID: 15294456
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antiobesity evaluation of histamine H3 receptor (H3R) antagonist analogs of A-331440 with improved safety and efficacy.
    Hancock AA; Diehl MS; Fey TA; Bush EN; Faghih R; Miller TR; Krueger KM; Pratt JK; Cowart MD; Dickinson RW; Shapiro R; Knourek-Segel VE; Droz BA; McDowell CA; Krishna G; Brune ME; Esbenshade TA; Jacobson PB
    Inflamm Res; 2005 Apr; 54 Suppl 1():S27-9. PubMed ID: 15928821
    [No Abstract]   [Full Text] [Related]  

  • 5. Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties.
    Esbenshade TA; Fox GB; Krueger KM; Miller TR; Kang CH; Denny LI; Witte DG; Yao BB; Pan L; Wetter J; Marsh K; Bennani YL; Cowart MD; Sullivan JP; Hancock AA
    J Pharmacol Exp Ther; 2005 Apr; 313(1):165-75. PubMed ID: 15608078
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects.
    Esbenshade TA; Krueger KM; Miller TR; Kang CH; Denny LI; Witte DG; Yao BB; Fox GB; Faghih R; Bennani YL; Williams M; Hancock AA
    J Pharmacol Exp Ther; 2003 Jun; 305(3):887-96. PubMed ID: 12606603
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Influence of a selective histamine H3 receptor antagonist on hypothalamic neural activity, food intake and body weight.
    Malmlöf K; Zaragoza F; Golozoubova V; Refsgaard HH; Cremers T; Raun K; Wulff BS; Johansen PB; Westerink B; Rimvall K
    Int J Obes (Lond); 2005 Dec; 29(12):1402-12. PubMed ID: 16151415
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of a novel Y5 antagonist in obese mice: combination with food restriction or sibutramine.
    Mashiko S; Ishihara A; Iwaasa H; Moriya R; Kitazawa H; Mitobe Y; Ito J; Gomori A; Matsushita H; Takahashi T; MacNeil DJ; Van der Ploeg LH; Fukami T; Kanatani A
    Obesity (Silver Spring); 2008 Jul; 16(7):1510-5. PubMed ID: 18421274
    [TBL] [Abstract][Full Text] [Related]  

  • 9. H3 receptor antagonists/inverse agonists as anti-obesity agents.
    Hancock AA
    Curr Opin Investig Drugs; 2003 Oct; 4(10):1190-7. PubMed ID: 14649210
    [TBL] [Abstract][Full Text] [Related]  

  • 10. G protein-dependent pharmacology of histamine H3 receptor ligands: evidence for heterogeneous active state receptor conformations.
    Krueger KM; Witte DG; Ireland-Denny L; Miller TR; Baranowski JL; Buckner S; Milicic I; Esbenshade TA; Hancock AA
    J Pharmacol Exp Ther; 2005 Jul; 314(1):271-81. PubMed ID: 15821027
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity.
    Morini G; Comini M; Rivara M; Rivara S; Bordi F; Plazzi PV; Flammini L; Saccani F; Bertoni S; Ballabeni V; Barocelli E; Mor M
    Bioorg Med Chem; 2008 Dec; 16(23):9911-24. PubMed ID: 18976927
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Distinctions and contradistinctions between antiobesity histamine H(3) receptor (H (3)R) antagonists compared to cognition-enhancing H (3) receptor antagonists.
    Hancock AA; Bitner RS; Krueger KM; Otte S; Nikkel AL; Fey TA; Bush EN; Dickinson RW; Shapiro R; Knourek-Segel V; Droz BA; Brune ME; Jacobson PB; Cowart MD; Esbenshade TA
    Inflamm Res; 2006 Apr; 55 Suppl 1():S42-4. PubMed ID: 16547814
    [No Abstract]   [Full Text] [Related]  

  • 13. 4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.
    Meier G; Krause M; Hüls A; Ligneau X; Pertz HH; Arrang JM; Ganellin CR; Schwartz JC; Schunack W; Stark H
    J Med Chem; 2004 May; 47(10):2678-87. PubMed ID: 15115409
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neurochemical and behavioral effects of ciproxifan, a potent histamine H3-receptor antagonist.
    Ligneau X; Lin J; Vanni-Mercier G; Jouvet M; Muir JL; Ganellin CR; Stark H; Elz S; Schunack W; Schwartz J
    J Pharmacol Exp Ther; 1998 Nov; 287(2):658-66. PubMed ID: 9808693
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increase of neuronal histamine in obese rats is associated with decreases in body weight and plasma triglycerides.
    Malmlöf K; Golozoubova V; Peschke B; Wulff BS; Refsgaard HH; Johansen PB; Cremers T; Rimvall K
    Obesity (Silver Spring); 2006 Dec; 14(12):2154-62. PubMed ID: 17189541
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist.
    Fox GB; Esbenshade TA; Pan JB; Radek RJ; Krueger KM; Yao BB; Browman KE; Buckley MJ; Ballard ME; Komater VA; Miner H; Zhang M; Faghih R; Rueter LE; Bitner RS; Drescher KU; Wetter J; Marsh K; Lemaire M; Porsolt RD; Bennani YL; Sullivan JP; Cowart MD; Decker MW; Hancock AA
    J Pharmacol Exp Ther; 2005 Apr; 313(1):176-90. PubMed ID: 15608077
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.
    Mikó T; Ligneau X; Pertz HH; Ganellin CR; Arrang JM; Schwartz JC; Schunack W; Stark H
    J Med Chem; 2003 Apr; 46(8):1523-30. PubMed ID: 12672253
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Histamine H(3) antagonists in models of obesity.
    Hancock AA; Bush EN; Jacobson PB; Faghih R; Esbenshade TA
    Inflamm Res; 2004 Mar; 53 Suppl 1():S47-8. PubMed ID: 15054613
    [No Abstract]   [Full Text] [Related]  

  • 19. Evidence for tolerance following repeated dosing in rats with ciproxifan, but not with A-304121.
    Pan JB; Yao BB; Miller TR; Kroeger PE; Bennani YL; Komater VA; Esbenshade TA; Hancock AA; Decker MW; Fox GB
    Life Sci; 2006 Aug; 79(14):1366-79. PubMed ID: 16730751
    [TBL] [Abstract][Full Text] [Related]  

  • 20. D-amino acid homopiperazine amides: discovery of A-320436, a potent and selective non-imidazole histamine H(3)-receptor antagonist.
    Curtis MP; Dwight W; Pratt J; Cowart M; Esbenshade TA; Krueger KM; Fox GB; Pan JB; Pagano TG; Hancock AA; Faghih R; Bennani YL
    Arch Pharm (Weinheim); 2004 Apr; 337(4):219-29. PubMed ID: 15146898
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.