BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 15034294)

  • 1. Glucocorticoids induce G1 arrest of lymphoblastic cells through retinoblastoma protein Rb1 dephosphorylation in childhood acute lymphoblastic leukemia in vivo.
    Addeo R; Casale F; Caraglia M; D'Angelo V; Crisci S; Abbruzzese A; Di Tullio MT; Indolfi P
    Cancer Biol Ther; 2004 May; 3(5):470-6. PubMed ID: 15034294
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.
    Sangfelt O; Erickson S; Castro J; Heiden T; Gustafsson A; Einhorn S; Grandér D
    Oncogene; 1999 May; 18(18):2798-810. PubMed ID: 10362250
    [TBL] [Abstract][Full Text] [Related]  

  • 3. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
    Akiyama T; Yoshida T; Tsujita T; Shimizu M; Mizukami T; Okabe M; Akinaga S
    Cancer Res; 1997 Apr; 57(8):1495-501. PubMed ID: 9108451
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TGF-beta-mediated cell cycle arrest of HPV16-immortalized human ectocervical cells correlates with decreased E6/E7 mRNA and increased p53 and p21(WAF-1) expression.
    Rorke EA; Zhang D; Choo CK; Eckert RL; Jacobberger JW
    Exp Cell Res; 2000 Aug; 259(1):149-57. PubMed ID: 10942587
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes.
    Singh RP; Agarwal C; Agarwal R
    Carcinogenesis; 2003 Mar; 24(3):555-63. PubMed ID: 12663518
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CDK2 catalytic activity and loss of nuclear tethering of retinoblastoma protein in childhood acute lymphoblastic leukemia.
    Schmitz NM; Leibundgut K; Hirt A
    Leukemia; 2005 Oct; 19(10):1783-7. PubMed ID: 16107892
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The retinoic acid receptor antagonist, BMS453, inhibits normal breast cell growth by inducing active TGFbeta and causing cell cycle arrest.
    Yang L; Ostrowski J; Reczek P; Brown P
    Oncogene; 2001 Nov; 20(55):8025-35. PubMed ID: 11753686
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest.
    Srethapakdi M; Liu F; Tavorath R; Rosen N
    Cancer Res; 2000 Jul; 60(14):3940-6. PubMed ID: 10919672
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transforming growth factor-beta1 up-regulates p15, p21 and p27 and blocks cell cycling in G1 in human prostate epithelium.
    Robson CN; Gnanapragasam V; Byrne RL; Collins AT; Neal DE
    J Endocrinol; 1999 Feb; 160(2):257-66. PubMed ID: 9924195
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BMP-7-induced cell cycle arrest of anaplastic thyroid carcinoma cells via p21(CIP1) and p27(KIP1).
    Franzén A ; Heldin NE
    Biochem Biophys Res Commun; 2001 Jul; 285(3):773-81. PubMed ID: 11453659
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of G1 phase arrest in MCF human breast cancer cells by pentagalloylglucose through the down-regulation of CDK4 and CDK2 activities and up-regulation of the CDK inhibitors p27(Kip) and p21(Cip).
    Chen WJ; Chang CY; Lin JK
    Biochem Pharmacol; 2003 Jun; 65(11):1777-85. PubMed ID: 12781329
    [TBL] [Abstract][Full Text] [Related]  

  • 12. G1 arrest by p16INK4A uncouples growth from cell cycle progression in leukemia cells with deregulated cyclin E and c-Myc expression.
    Ausserlechner MJ; Obexer P; Geley S; Kofler R
    Leukemia; 2005 Jun; 19(6):1051-7. PubMed ID: 15800668
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
    Rao S; Lowe M; Herliczek TW; Keyomarsi K
    Oncogene; 1998 Nov; 17(18):2393-402. PubMed ID: 9811471
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia.
    Rhein P; Scheid S; Ratei R; Hagemeier C; Seeger K; Kirschner-Schwabe R; Moericke A; Schrappe M; Spang R; Ludwig WD; Karawajew L
    Leukemia; 2007 May; 21(5):897-905. PubMed ID: 17330098
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypermethylation of p16 and p15 genes and RB protein expression in acute leukemia.
    Guo SX; Taki T; Ohnishi H; Piao HY; Tabuchi K; Bessho F; Hanada R; Yanagisawa M; Hayashi Y
    Leuk Res; 2000 Jan; 24(1):39-46. PubMed ID: 10634644
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein.
    Reshetnikova G; Barkan R; Popov B; Nikolsky N; Chang LS
    Exp Cell Res; 2000 Aug; 259(1):35-53. PubMed ID: 10942577
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Limited redundancy in phosphorylation of retinoblastoma tumor suppressor protein by cyclin-dependent kinases in acute lymphoblastic leukemia.
    Schmitz NM; Hirt A; Aebi M; Leibundgut K
    Am J Pathol; 2006 Sep; 169(3):1074-9. PubMed ID: 16936279
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The cancer preventive flavonoid silibinin causes hypophosphorylation of Rb/p107 and Rb2/p130 via modulation of cell cycle regulators in human prostate carcinoma DU145 cells.
    Tyagi A; Agarwal C; Agarwal R
    Cell Cycle; 2002; 1(2):137-42. PubMed ID: 12429923
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Initial leukemic gene expression profiles of patients with poor in vivo prednisone response are similar to those of blasts persisting under prednisone treatment in childhood acute lymphoblastic leukemia.
    Cario G; Fetz A; Bretscher C; Möricke A; Schrauder A; Stanulla M; Schrappe M
    Ann Hematol; 2008 Sep; 87(9):709-16. PubMed ID: 18521602
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.
    Sengupta TK; Leclerc GM; Hsieh-Kinser TT; Leclerc GJ; Singh I; Barredo JC
    Mol Cancer; 2007 Jul; 6():46. PubMed ID: 17623090
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.